Audiovisual integration increases the intentional step synchronization of side-by-side walkers

When people walk side-by-side, they often synchronize their steps. To achieve this, individuals might cross-modally match audiovisual signals from the movements of the partner and kinesthetic, cutaneous, visual and auditory signals from their own movements. Because signals from different sensory systems are processed with noise and asynchronously, the challenge of the CNS is to derive the best estimate based on this conflicting information. This is currently thought to be done by a mechanism operating as a Maximum Likelihood Estimator (MLE). The present work investigated whether audiovisual signals from the partner are integrated according to MLE in order to synchronize steps during walking. Three experiments were conducted in which the sensory cues from a walking partner were virtually simulated. In Experiment 1 seven participants were instructed to synchronize with human-sized Point Light Walkers and/or footstep sounds. Results revealed highest synchronization performance with auditory and audiovisual cues. This was quantified by the time to achieve synchronization and by synchronization variability. However, this auditory dominance effect might have been due to artifacts of the setup. Therefore, in Experiment 2 human-sized virtual mannequins were implemented. Also, audiovisual stimuli were rendered in real-time and thus were synchronous and co-localized. All four participants synchronized best with audiovisual cues. For three of the four participants results point toward their optimal integration consistent with the MLE model. Experiment 3 yielded performance decrements for all three participants when the cues were incongruent. Overall, these findings suggest that individuals might optimally integrate audiovisual cues to synchronize steps during side-by-side walking.info:eu-repo/semantics/publishedVersio

Fermi surface instabilities at finite Temperature

We present a new method to detect Fermi surface instabilities for interacting systems at finite temperature. We first apply it to a list of cases studied previously, recovering already known results in a very economic way, and obtaining most of the information on the phase diagram analytically. As an example, in the continuum limit we obtain the critical temperature as an implicit function of the magnetic field and the chemical potential $T_c(\mu,h)$. By applying the method to a model proposed to describe reentrant behavior in $Sr_3Ru_2O_7$, we reproduce the phase diagram obtained experimentally and show the presence of a non-Fermi Liquid region at temperatures above the nematic phase.Comment: 10 pages, 10 figure

Impact of occlusion duration on the success rate and outcomes of percutaneous coronary intervention in chronic total occlusions

ABSTRACTBackgroundInitial studies have shown that old occlusions or those with indeterminate occlusion duration have been associated with percutaneous coronary intervention (PCI) failure and a worse prognosis. This study aimed to determine the impact of occlusion duration on the success and outcomes of contemporary PCI on chronic total occlusion (CTO).MethodsThe authors analyzed a retrospective cohort of consecutive patients submitted to PCI in CTO, who were compared according to the confirmed occlusion duration (COD) < 12 months, ≥ 12 months, or indeterminate occlusion duration (IOD).ResultsA total of 168 patients were treated, 122 (72.6%) with COD (80 < 12 months, 42 ≥ 12 months) and 46 (24.7%) with an IOD. Lesion extension was 17.0 ± 13.6mm, in 2.90 ± 0.58mm vessels, and the anterograde approach was used in 98.8% of cases. Angiographic success was attained in 79.2% of patients (80.0% vs. 73.8% vs. 82.6%; p = 0.73). The main cause of failure was the inability to cross the lesion with the guidewire (68.6%). Occlusion duration had no impact on in-hospital events (4.8% vs. 7.1% vs. 6.0%; p = 0.73), which were almost entirely explained by periprocedural myocardial infarction, or on late outcomes (18.8% vs. 7.1% vs. 15.3%; p = 0.23). At the multivariate analysis, lesion length ≥ 20mm (odds ratio - OR = 7.27; 95% confidence interval - 95% IC 1.94-29.1; p = 0.003), calcification (OR = 4.72; 95% CI 1.19-19.1; p = 0.02), and tortuosity of the occluded segment (OR = 15.98; 95% CI 2.18-144.7; p = 0.007) were predictors of failure.ConclusionsOcclusion duration was not associated with increased failure rate of the procedure or worse PCI outcomes in CTO

Robust generation of entanglement between two cavities mediated by short interactions with an atom

Published versio

Realidad aumentada: innovación educativa en las aulas jujeñas

Las computadoras y las nuevas tecnologías en la educación pueden ser vistas como herramientas y materiales de construcción que facilitan el aprendizaje y el desarrollo de habilidades; constituyendo distintas formas de aprender de los alumnos y no deben ser consideradas como un fin, sino como un medio. Se busca utilizar estas herramientas para promover, facilitar y enriquecer la comprensión de temas y conceptos propios e importantes de las diferentes asignaturas curriculares dentro del proceso educativo. Este trabajo se centra en la introducción y aplicación de Realidad Aumentada como nueva tecnología que puede incorporarse en el proceso de enseñanza y aprendizaje dentro del sistema Educativo, mediante la combinación de diferentes tipos de materiales (auditivos, visuales y audiovisuales).Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

Realidad aumentada: innovación educativa en las aulas jujeñas

Las computadoras y las nuevas tecnologías en la educación pueden ser vistas como herramientas y materiales de construcción que facilitan el aprendizaje y el desarrollo de habilidades; constituyendo distintas formas de aprender de los alumnos y no deben ser consideradas como un fin, sino como un medio. Se busca utilizar estas herramientas para promover, facilitar y enriquecer la comprensión de temas y conceptos propios e importantes de las diferentes asignaturas curriculares dentro del proceso educativo. Este trabajo se centra en la introducción y aplicación de Realidad Aumentada como nueva tecnología que puede incorporarse en el proceso de enseñanza y aprendizaje dentro del sistema Educativo, mediante la combinación de diferentes tipos de materiales (auditivos, visuales y audiovisuales).Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

Realidad aumentada: innovación educativa en las aulas jujeñas

Las computadoras y las nuevas tecnologías en la educación pueden ser vistas como herramientas y materiales de construcción que facilitan el aprendizaje y el desarrollo de habilidades; constituyendo distintas formas de aprender de los alumnos y no deben ser consideradas como un fin, sino como un medio. Se busca utilizar estas herramientas para promover, facilitar y enriquecer la comprensión de temas y conceptos propios e importantes de las diferentes asignaturas curriculares dentro del proceso educativo. Este trabajo se centra en la introducción y aplicación de Realidad Aumentada como nueva tecnología que puede incorporarse en el proceso de enseñanza y aprendizaje dentro del sistema Educativo, mediante la combinación de diferentes tipos de materiales (auditivos, visuales y audiovisuales).Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)

Although considerable improvement has occurred in the process of care for patients with ST-elevation myocardial infarction (STEMI), room for improvement exists (1–3). The purpose of the present guideline is to focus on the numerous advances in the diagnosis and management of patients with STEMI since 1999. This is reflected in the changed name of the guideline: “ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction.” The final recommendations for indications for a diagnostic procedure, a particular therapy, or an intervention in patients with STEMI summarize both clinical evidence and expert opinion (Table 1).To provide clinicians with a set of recommendations that can easily be translated into the practice of caring for patients with STEMI, this guideline is organized around the chronology of the interface between the patient and the clinician. The full guideline is available at http://www.acc.org/clinical/guidelines/stemi/index.htm

Differential body composition effects of protease inhibitors recommended for initial treatment of HIV infection: A randomized clinical trial

This article has been accepted for publication in Clinical Infectious Diseases ©2014 The Authors .Published by Oxford University Press on Clinical Infectious Disease 60.5. DOI: 10.1093/cid/ciu898Background. It is unclear whether metabolic or body composition effects may differ between protease inhibitor-based regimens recommended for initial treatment of HIV infection. Methods. ATADAR is a phase IV, open-label, multicenter randomized clinical trial. Stable antiretroviral-naive HIV-infected adults were randomly assigned to atazanavir/ritonavir 300/100 mg or darunavir/ritonavir 800/100 mg in combination with tenofovir/emtricitabine daily. Pre-defined end-points were treatment or virological failure, drug discontinuation due to adverse effects, and laboratory and body composition changes at 96 weeks. Results. At 96 weeks, 56 (62%) atazanavir/ritonavir and 62 (71%) darunavir/ritonavir patients remained free of treatment failure (estimated difference 8.2%; 95%CI -0.6 to 21.6); and 71 (79%) atazanavir/ritonavir and 75 (85%) darunavir/ritonavir patients remained free of virological failure (estimated difference 6.3%; 95%CI -0.5 to 17.6). Seven vs. five patients discontinued atazanavir/ritonavir or darunavir/ritonavir due to adverse effects. Total and HDL cholesterol similarly increased in both arms, but triglycerides increased more in atazanavir/ritonavir arm. At 96 weeks, body fat (estimated difference 2862.2 gr; 95%CI 726.7 to 4997.7; P=0.0090), limb fat (estimated difference 1403.3 gr; 95%CI 388.4 to 2418.2; P=0.0071), and subcutaneous abdominal adipose tissue (estimated difference 28.4 cm2; 95%CI 1.9 to 55.0; P=0.0362) increased more in atazanavir/ritonavir than in darunavir/ritonavir arm. Body fat changes in atazanavir/ritonavir arm were associated with higher insulin resistance. Conclusions. We found no major differences between atazanavir/ritonavir and darunavir/ritonavir in efficacy, clinically-relevant side effects, or plasma cholesterol fractions. However, atazanavir/ritonavir led to higher triglycerides and total and subcutaneous fat than darunavir/ritonavir and fat gains with atazanavir/ritonavir were associated with insulin resistanceThis is an Investigator Sponsored Research study. It was supported in part by research grants from Bristol‐Myers Squibb and Janssen‐Cilag; Instituto de Salud Carlos III (PI12/01217) and Red Temática Cooperativa de Investigación en SIDA G03/173 (RIS‐EST11), Ministerio de Ciencia e Innovación, Spain. (Registration number: NCT01274780; registry name: ATADAR; EUDRACT; 2010‐021002‐38)