15,368 research outputs found

    Recovery of continuous wave squeezing at low frequencies

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    We propose and demonstrate a system that produces squeezed vacuum using a pair of optical parametric amplifiers. This scheme allows the production of phase sidebands on the squeezed vacuum which facilitate phase locking in downstream applications. We observe strong, stably locked, continuous wave vacuum squeezing at frequencies as low as 220 kHz. We propose an alternative resonator configuration to overcome low frequency squeezing degradation caused by the optical parametric amplifiers.Comment: 9 pages, 4 figure

    Surgical treatment of a paraspinal abscess with osteomyelitis and spinal cord compression in a rabbit

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    Unification of bulk and interface electroresistive switching in oxide systems

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    We demonstrate that the physical mechanism behind electroresistive switching in oxide Schottky systems is electroformation, as in insulating oxides. Negative resistance shown by the hysteretic current-voltage curves proves that impact ionization is at the origin of the switching. Analyses of the capacitance-voltage and conductance-voltage curves through a simple model show that an atomic rearrangement is involved in the process. Switching in these systems is a bulk effect, not strictly confined at the interface but at the charge space region.Comment: 4 pages, 3 figures, accepted in PR

    Schubert Polynomials for the affine Grassmannian of the symplectic group

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    We study the Schubert calculus of the affine Grassmannian Gr of the symplectic group. The integral homology and cohomology rings of Gr are identified with dual Hopf algebras of symmetric functions, defined in terms of Schur's P and Q-functions. An explicit combinatorial description is obtained for the Schubert basis of the cohomology of Gr, and this is extended to a definition of the affine type C Stanley symmetric functions. A homology Pieri rule is also given for the product of a special Schubert class with an arbitrary one.Comment: 45 page

    Multi-domain active sound control and noise shielding

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    This paper describes an active sound control methodology based on difference potentials. The main feature of this methodology is its ability to automatically preserve “wanted” sound within a domain while canceling “unwanted” noise from outside the domain. This method of preservation of the wanted sounds by active shielding control is demonstrated with various broadband and realistic sound sources such as human voice and music in multiple domains in a one-dimensional enclosure. Unlike many other conventional active control methods, the proposed approach does not require the explicit characterization of the wanted sound to be preserved. The controls are designed based on the measurements of the total field on the boundaries of the shielded domain only, which is allowed to be multiply connected. The method is tested in a variety of experimental cases. The typical attenuation of the unwanted noise is found to be about 20 dB over a large area of the shielded domain and the original wanted sound field is preserved with errors of around 1 dB and below through a broad frequency range up to 1 kHz. © 2011 Acoustical Society of Americ

    Higher-order non-symmetric counterterms in pure Yang-Mills theory

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    We analyze the restoration of the Slavnov-Taylor (ST) identities for pure massless Yang-Mills theory in the Landau gauge within the BPHZL renormalization scheme with IR regulator. We obtain the most general form of the action-like part of the symmetric regularized action, obeying the relevant ST identities and all other relevant symmetries of the model, to all orders in the loop expansion. We also give a cohomological characterization of the fulfillment of BPHZL IR power-counting criterion, guaranteeing the existence of the limit where the IR regulator goes to zero. The technique analyzed in this paper is needed in the study of the restoration of the ST identities for those models, like the MSSM, where massless particles are present and no invariant regularization scheme is known to preserve the full set of ST identities of the theory.Comment: Final version published in the journa

    XAX: a multi-ton, multi-target detection system for dark matter, double beta decay and pp solar neutrinos

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    A multi-target detection system XAX, comprising concentric 10 ton targets of 136Xe and 129/131Xe, together with a geometrically similar or larger target of liquid Ar, is described. Each is configured as a two-phase scintillation/ionization TPC detector, enhanced by a full 4pi array of ultra-low radioactivity Quartz Photon Intensifying Detectors (QUPIDs) replacing the conventional photomultipliers for detection of scintillation light. It is shown that background levels in XAX can be reduced to the level required for dark matter particle (WIMP) mass measurement at a 10^-10 pb WIMP-nucleon cross section, with single-event sensitivity below 10^-11 pb. The use of multiple target elements allows for confirmation of the A^2 dependence of a coherent cross section, and the different Xe isotopes provide information on the spin-dependence of the dark matter interaction. The event rates observed by Xe and Ar would modulate annually with opposite phases from each other for WIMP mass >~100 GeV/c^2. The large target mass of 136Xe and high degree of background reduction allow neutrinoless double beta decay to be observed with lifetimes of 10^27-10^28 years, corresponding to the Majorana neutrino mass range 0.01-0.1 eV, the most likely range from observed neutrino mass differences. The use of a 136Xe-depleted 129/131Xe target will also allow measurement of the pp solar neutrino spectrum to a precision of 1-2%.Comment: 16 pages with 17 figure

    Squeezing and entanglement delay using slow light

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    We examine the interaction of a weak probe with NN atoms in a lambda-level configuration under the conditions of electromagnetically induced transparency (EIT). In contrast to previous works on EIT, we calculate the output state of the resultant slowly propagating light field while taking into account the effects of ground state dephasing and atomic noise for a more realistic model. In particular, we propose two experiments using slow light with a nonclassical probe field and show that two properties of the probe, entanglement and squeezing, characterizing the quantum state of the probe field, can be well-preserved throughout the passage.Comment: 2 figures; v2: fixed some minor typographical errors in a couple of equations and corrected author spelling in one reference. v3: Added three authors; changed the entaglement definition to conform to a more accepted standard (Duan's entanglement measure); altered the abstract slightly. v4: fixed formatting of figure

    A pseudo-spectral approach to inverse problems in interface dynamics

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    An improved scheme for computing coupling parameters of the Kardar-Parisi-Zhang equation from a collection of successive interface profiles, is presented. The approach hinges on a spectral representation of this equation. An appropriate discretization based on a Fourier representation, is discussed as a by-product of the above scheme. Our method is first tested on profiles generated by a one-dimensional Kardar-Parisi-Zhang equation where it is shown to reproduce the input parameters very accurately. When applied to microscopic models of growth, it provides the values of the coupling parameters associated with the corresponding continuum equations. This technique favorably compares with previous methods based on real space schemes.Comment: 12 pages, 9 figures, revtex 3.0 with epsf style, to appear in Phys. Rev.

    Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor.

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    Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong survival and metastasis signal in human prostate cancer cells, and to confer androgen independence and drug resistance. While the role of Etk in prostate carcinogenesis is well established, the functions of Btk in prostate cancer have never been investigated, likely due to the perception that Btk is a hematopoietic, but not epithelial, kinase. Herein, we found that Btk is overexpressed in prostate cancer tissues and prostate cancer cells. The level of Btk in prostate cancer tissues correlates with cancer grades. Knockdown of Btk expression selectively inhibits the growth of prostate cancer cells, but not that of the normal prostate epithelial cells, which express very little Btk. Dual inhibition of Btk and Etk has an additive inhibitory effect on prostate cancer cell growth. To explore Btk and Etk as targets for prostate cancer, we developed a small molecule dual inhibitor of Btk and Etk, CTN06. Treatment of PC3 and other prostate cancer cells, but not immortalized prostate epithelial cells with CTN06 resulted in effective cell killing, accompanied by the attenuation of Btk/Etk signals. The killing effect of CTN06 is more potent than that of commonly used inhibitors against Src, Raf/VEGFR and EGFR. CTN06 induces apoptosis as well as autophagy in human prostate cancer cells, and is a chemo-sensitizer for docetaxel (DTX), a standard of care for metastatic prostate cancer patients. CTN06 also impeded the migration of human prostate cancer cells based on a 'wound healing' assay. The anti-cancer effect of CTN06 was further validated in vivo in a PC3 xenograft mouse model
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