EVALUATING THE RELATIONSHIP BETWEEN HYPERTENSION AND BLOOD GLUCOSE LEVEL- A DESCRIPTIVE CORRELATIONAL STUDY.

Background: Hyperglycemia is a condition where the body experiences an increase in blood glucose levels and insulin can’t be used appropriately. Patients with diabetes mellitus experience hyperglycemia where there is an increased level of angiotensin hormone which can cause hypertension. The main approach of this study is to correlate the association of blood glucose levels with hypertension. Materials and methods: The type of this study was descriptive correlation. A total of 210 subjects were selected for this study of which only 166 samples were the responders and a Random sampling technique was used to analyze the subjects. The level of blood glucose was examined with semi-automated analyzer and a sphygmomanometer was used for blood pressure analysis. Results: The obtained data were integrated with “The Pearson correlation test”. Of the total population included in this study, females were the responders and most of the responders had “Diabetes mellitus”. Conclusions: Samples with high levels of blood glucose had a great risk of high blood pressure. The level of Blood glucose is interrelated with the level of blood pressure in individuals with the condition of hypertension. Recommendation: It is recommended for aged people to always maintain their blood glucose level to lower their risk of cardiovascular diseases including hypertension

ASSOCIATION OF SERUM CHLORIDE LEVEL WITH HYPERTENSION.

Background: The most abundant anion in our body, along with sodium, is chloride (Cl), which is primarily obtained through dietary sources. Studies indicate that greater dietary Chloride intake raises blood pressure, and higher serum Cl seems to be linked to decreased cardiovascular risk and death. This indicates that serum Chloride reflects risk pathways independent of blood pressure, serum sodium, and serum bicarbonate. It is uncertain how serum chloride affects a patient's long-term survival after developing pulmonary arterial hypertension. Methods: This study included patients with hypertension, idiopathic or heritable, who had a basic metabolic panel when they were diagnosed with hypertension. Results: Over time, serum chloride had no obvious impact on systolic blood pressure. Only serum bicarbonate among electrolytes demonstrated an independent impact on longitudinal blood pressure. Conclusion: This study has shown the association of chloride with systolic and diastolic blood pressure. Recommendation: More studies are now needed to elucidate the mechanisms of the association between low serum Chloride levels and mortality outcomes if more studies confirm and extend our findings. Our findings may be applied in clinical practice to recognize persons with high-risk hypertension as Chloride measurement is a critical component of routine clinical screening.

A Novel System for Growth of Single Crystals from the Melt with an Innovative New Pulling Mechanism

665-670This paper describes a crystal growth system employing novel concepts in fabrication of a high temperature furnace, thermocouples and a novel crystal pulling mechanism. This has reduced the costs substantially, without compromising the quality of grown crystals. The core of the furnace, a wooden cylindrical dummy had been prepared with equi-spaced helical groves with widths equaling the diameter of the heating wire on its outer surface machined by a lathe machine. The Kanthal heating wire was wound in the groves. It was covered with a thick layer of natural clay available locally. After the clay had dried up, an electric current was passed through the heating wire and the wooden frame was burnt out. A thick layer of the clay was applied on the inner and the outer surfaces. The furnace can operate at temperatures up to about 1000 °C. The temperature was measured with a chromel-alumel thermocouple prepared by an ingenious spot-welding technique established in the laboratory. The seed holder was hanged above the melt kept in the crucible with help of a float kept in a water container, which has a small tap at the bottom. When the tap is opened the float goes down and the seed assembly goes up. In this manner a quality pulling system, without any motor has been developed and reported here. It has been possible to grow good quality crystals of potassium chloride with excellent diameter control

A Novel System for Growth of Single Crystals from the Melt with an Innovative New Pulling Mechanism

This paper describes a crystal growth system employing novel concepts in fabrication of a high temperature furnace, thermocouples and a novel crystal pulling mechanism. This has reduced the costs substantially, without compromising the quality of grown crystals. The core of the furnace, a wooden cylindrical dummy had been prepared with equi-spaced helicalgroves with widths equaling the diameter of the heating wire on its outer surface machined by a lathe machine. The Kanthal heating wire was wound in the groves. It was covered with a thick layer of natural clay available locally. After the clay had dried up, an electric current was passed through the heating wire and the wooden frame was burnt out. A thick layer of theclay was applied on the inner and the outer surfaces. The furnace can operate at temperatures up to about 1000 °C. The temperature was measured with a chromel-alumel thermocouple prepared by an ingenious spot-welding technique established in the laboratory. The seed holder was hanged above the melt kept in the crucible with help of a float kept in awater container, which has a small tap at the bottom. When the tap is opened the float goes down and the seed assembly goes up. In this manner a quality pulling system, without any motor has been developed and reported here. It has been possible to grow good quality crystals of potassium chloride with excellent diameter control

Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3′UTR

MicroRNAs (miRNAs) are 21–22 nucleotide regulatory small RNAs that repress message translation via base-pairing with complementary sequences in the 3′ untranslated region (3′UTR) of targeted transcripts. To date, it is still difficult to find a true miRNA target due to lack of a clear understanding of how miRNAs functionally interact with their targeted transcripts for efficient repression. Previous studies have shown that nucleotides 2 to 7 at the 5′-end of a mature miRNA, the ‘seed sequence’, can nucleate miRNA/target interactions. In the current study, we have validated that the RhoB mRNA is a bona fide miR-223 target. We have analyzed the functional activities of two miR223-binding sites within the RhoB 3′UTR. We find that the two miR-223 target sites in the RhoB 3′UTR contribute differentially to the total repression of RhoB translation. Moreover, we demonstrate that some AU-rich motifs located upstream of the distal miRNA-binding site enhance miRNA function, independent of the miRNA target sequences being tested. We also demonstrate that the AU-rich sequence elements are polar, and do not affect the activities of miRNAs whose sites lie upstream of these elements. These studies provide further support for the role of sequences outside of miRNA target region influencing miRNA function

How 'dynasty' became a modern global concept : intellectual histories of sovereignty and property

The modern concept of ‘dynasty’ is a politically-motivated modern intellectual invention. For many advocates of a strong sovereign nation-state across the nineteenth and early twentieth century, in France, Germany, and Japan, the concept helped in visualizing the nation-state as a primordial entity sealed by the continuity of birth and blood, indeed by the perpetuity of sovereignty. Hegel’s references to ‘dynasty’, read with Marx’s critique, further show how ‘dynasty’ encoded the intersection of sovereignty and big property, indeed the coming into self-consciousness of their mutual identification-in-difference in the age of capitalism. Imaginaries about ‘dynasty’ also connected national sovereignty with patriarchal authority. European colonialism helped globalize the concept in the non-European world; British India offers an exemplar of ensuing debates. The globalization of the abstraction of ‘dynasty’ was ultimately bound to the globalization of capitalist-colonial infrastructures of production, circulation, violence, and exploitation. Simultaneously, colonized actors, like Indian peasant/‘tribal’ populations, brought to play alternate precolonial Indian-origin concepts of collective regality, expressed through terms like ‘rajavamshi’ and ‘Kshatriya’. These concepts nourished new forms of democracy in modern India. Global intellectual histories can thus expand political thought today by provincializing and deconstructing Eurocentric political vocabularies and by recuperating subaltern models of collective and polyarchic power.PostprintPeer reviewe