79 research outputs found
Leeds: a geological background for planning and development : 1:10000 sheets SE23NW, NE, SE and SE33NW, NE, SW, SE: parts of 1:50000 geological sheets 69 (Bradford), 70 (Leeds), 77 (Huddersfield) and 78 (Wakefield)
This study, carried out between 1989 and 1991, was commissioned by the Department of the Environment and funded
jointly by the Department and the British Geological Survey. Its principal aim was to produce a synthesis of geological information relevant to the land-use planning for
development and redevelopment for a large part of the
Leeds district. This report is aimed at those involved in
planning and development. Much of the information is provided on a series of thematic maps, each of which concentrates on a specific aspect of the geology relevant to landuse. These are suitable for use in forward planning for development and conservation, and as a background to desk studies, prepared in advance of specific development proposals. However, they must not be used in place of results of adequate site investigations when development is being considered. In addition to the information contained in the report, sources of other more detailed data are indicated
Geological notes and local details for 1:10,000 sheets SU60NE, SE, SU61SE, SU70NW, NE, SW, SE, SU71SW, SZ69NE and SZ79NW, NE: the south-east Hampshire district: Havant and surrounding areas: part of 1:50,000 sheets 316 (Fareham) and 331 (Portsmouth)
This report describes the geology of a group of eleven
National Grid 1:10 000 sheet areas as follows: SU60NE, SE; SU61SE; SU70NW, NE, SW, SE; SU71SW; SZ69NE and SZ79 NW, NE. These cover the coastal area of Portsea, Hayling and Thorney Islands, the eastern part of the Forest of Bere and the eastern part of Portsdown. The area reported on includes parts of 1:50 000 Geological Sheets 316) (Fareham) and 331 (Portsmouth)
QED3 theory of underdoped high temperature superconductors
Low-energy theory of d-wave quasiparticles coupled to fluctuating vortex
loops that describes the loss of phase coherence in a two dimensional d-wave
superconductor at T=0 is derived. The theory has the form of 2+1 dimensional
quantum electrodynamics (QED3), and is proposed as an effective description of
the T=0 superconductor-insulator transition in underdoped cuprates. The
coupling constant ("charge") in this theory is proportional to the dual order
parameter of the XY model, which is assumed to be describing the quantum
fluctuations of the phase of the superconducting order parameter. The principal
result is that the destruction of phase coherence in d-wave superconductors
typically, and immediately, leads to antiferromagnetism. The transition can be
understood in terms of the spontaneous breaking of an approximate "chiral"
SU(2) symmetry, which may be discerned at low enough energies in the standard
d-wave superconductor. The mechanism of the symmetry breaking is analogous to
the dynamical mass generation in the QED3, with the "mass" here being
proportional to staggered magnetization. Other insulating phases that break
chiral symmetry include the translationally invariant "d+ip" and "d+is"
insulators, and various one dimensional charge-density and spin-density waves.
The theory offers an explanation for the rounded d-wave-like dispersion seen in
ARPES experiments on Ca2CuO2Cl2 (F. Ronning et. al., Science 282, 2067 (1998)).Comment: Revtex, 20 pages, 5 figures; this is a much extended follow-up to the
Phys. Rev. Lett. vol.88, 047006 (2002) (cond-mat/0110188); improved
presentation, many additional explanations, comments, and references added,
sec. IV rewritten. Final version, to appear in Phys. Rev.
Low-frequency dilatational wave propagation through unsaturated porous media containing two immiscible fluids
Reforming Watershed Restoration: Science in Need of Application and Applications in Need of Science
Effect of short period feed supplementation during early lactation on performance of cows and calves raised in extensive system
Comparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals(1). Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monkeys and mice, we demonstrate a broadly conserved cellular makeup of this region, with similarities that mirror evolutionary distance and are consistent between the transcriptome and epigenome. The core conserved molecular identities of neuronal and non-neuronal cell types allow us to generate a cross-species consensus classification of cell types, and to infer conserved properties of cell types across species. Despite the overall conservation, however, many species-dependent specializations are apparent, including differences in cell-type proportions, gene expression, DNA methylation and chromatin state. Few cell-type marker genes are conserved across species, revealing a short list of candidate genes and regulatory mechanisms that are responsible for conserved features of homologous cell types, such as the GABAergic chandelier cells. This consensus transcriptomic classification allows us to use patch-seq (a combination of whole-cell patch-clamp recordings, RNA sequencing and morphological characterization) to identify corticospinal Betz cells from layer 5 in non-human primates and humans, and to characterize their highly specialized physiology and anatomy. These findings highlight the robust molecular underpinnings of cell-type diversity in M1 across mammals, and point to the genes and regulatory pathways responsible for the functional identity of cell types and their species-specific adaptations.Cardiovascular Aspects of Radiolog
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes
Lymphoma risk is elevated for relatives with common non-Hodgkin lymphoma (NHL) subtypes, suggesting shared genetic susceptibility across subtypes. To evaluate the extent of mutual heritability among NHL subtypes and discover novel loci shared among subtypes, we analyzed data from eight genome-wide association studies within the InterLymph Consortium, including 10,629 cases and 9505 controls. We utilized Association analysis based on SubSETs (ASSET) to discover loci for subsets of NHL subtypes and evaluated shared heritability across the genome using Genome-wide Complex Trait Analysis (GCTA) and polygenic risk scores. We discovered 17 genome-wide significant loci (P < 5 × 10−8) for subsets of NHL subtypes, including a novel locus at 10q23.33 (HHEX) (P = 3.27 × 10−9). Most subset associations were driven primarily by only one subtype. Genome-wide genetic correlations between pairs of subtypes varied broadly from 0.20 to 0.86, suggesting substantial heterogeneity in the extent of shared heritability among subtypes. Polygenic risk score analyses of established loci for different lymphoid malignancies identified strong associations with some NHL subtypes (P < 5 × 10−8), but weak or null associations with others. Although our analyses suggest partially shared heritability and biological pathways, they reveal substantial heterogeneity among NHL subtypes with each having its own distinct germline genetic architecture
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