Building A Bridge: Customized Programs And First-Year Undergraduate Students

Vermont-based SIT Study Abroad is a service provider in over 40 countries offering study abroad programs to undergraduate students. New trends in the study abroad field have driven some of the focus of study abroad participation from the junior year abroad to first-year undergraduate students. While higher education institutions push for more students to study abroad, limited resources and the desire for a wider variety of program types lead them to third-party providers such as SIT Study Abroad. This capstone paper examines the new focus on first-year undergraduates and the necessity for SIT Study Abroad to offer customized programs to meet partner needs. The designed program offers first-year undergraduate students an international structure on which to construct their intercultural, linguistic, and academic skills. The program aims to build a bridge between the high school experience and entrance into the undergraduate classroom. SIT Study Abroad and Brandeis University are partnering to offer a program in David, Panama to increase student recognition of the interdisciplinary nature of academics and problem solving in today’s world. The collaboration with Brandeis University allows SIT Study Abroad to expand its current portfolio of programming and increase services available to partner institutions. In order to meet the needs of partner institutions and continue to increase new program development, SIT Study Abroad is focusing on customized program development. New resources and attention have been given to processes and systems that are necessary in order to successfully implement customized programs. The development of the first-year undergraduate program and the customized program model positions SIT Study Abroad to meet the needs of the current study abroad environment

Moonscape

Moonscape is a short novel exploring the interplay of incest and prostitution. The novel is set in Las Vegas in the late seventies, with flashbacks to the thirties when Hoover Dam was built. The thesis relies on first person narratives to incorporate three points of view; two feminine, one masculine. The inspiration for the novel comes from William Faulkner\u27s Absalom! Absalom!, but the form and setting for the piece follows T. S. Eliot\u27s poem, The Wasteland . One character is patterned after Eliot\u27s Sweeney, the heathen pragmatist who appears throughout his poetry until 1927, the year of Eliot\u27s conversion to Anglicanism. The themes of sin and forgiveness form the focus of the novel

Reducing Hospital Readmissions in New York State: A Simulation Analysis of Alternative Payment Incentives

Examines strategies to reduce hospital readmissions, including improving discharge processes, post-discharge support, and payment incentives. Estimates payers' and hospitals' cost savings from pay-for-performance and episode-based payments

Influencing Student Beliefs about Poverty and Health through Interprofessional Community-Based Educational Experiences

Background: Pre-licensure students from medicine, physical therapy, kinesiology, nursing, and social work participated in a population health project at the University of Saskatchewan. We assessed the effect of this interactive, interprofessional, community-based educational experience on students’ attitudes and beliefs about poverty and health.Methods and Findings: Participants (N = 119) completed two measures at the beginning and end of the five-week project: the 37-item Attitudes toward Poverty Scale (APS) and the 8-item Beliefs about the Relationship between Poverty and Health (BRPH). APS scores showed a modest significant increase toward more positive attitudes over time (F(1, 110) = 7.97, p < .01). On the BRPH, participants agreed significantly less at Week 5 with two behavioral explanations (F(1, 114) = 5.07, p < .05; F(1, 114) = 11.00, p < .01) and one structural explanation (F(1, 112) = 11.09, p < .01) about relationships between poverty and health. There was some evidence that face-to-face interactions with community members had more impact than a simulation exercise. Students gave positive evaluations of the interprofessional format of the project. Attrition effects may limit the interpretation of these results.Conclusions: Results demonstrate that brief interprofessional community-based learning experiences can positively influence students’ attitudes and beliefs about the relationship between poverty and health

Survey of Interprofessional Collaboration Learning Needs and Training Interest in Health Professionals, Teachers, and Students: An Exploratory Study

AbstractBackground: Researchers and trainers from many professions and settings have emphasized the importance of explicit training in interprofessional collaboration (IPC), but interest in and best practice for training for IPC remains unknown.Methods and Findings: A 33-item Internet-based survey was completed by 486 practicing professionals and students from the sectors of health and education. The survey assessed experiences and knowledge of IPC as well as interest in and barriers to further training in IPC. Overall, there was agreement among respondents regarding the importance of IPC. Satisfaction with IPC was associated with higher self-ratings of knowledge and skills related to IPC. Interest in further IPC training was high, especially for one- or two-day workshops or web-based modules. Qualitative analysis of responses to an open-ended question about IPC skills and knowledge revealed seven networks of common themes that can serve as a framework for training and theory development.Conclusions: IPC training should provide knowledge about IPC models and research, leadership styles, team stages, and conflict management, while also ensuring that training applies to the workplace or practicum placement. Efforts should be made to promote awareness of the need for training in areas where trainees already feel competent

Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy

Background: The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into the mechanism of the receptor as well as for potentially interfering with its function for therapeutic purposes. Methodology/Principal Findings: We used the Affinity Grid approach to prepare specimens of the Notch extracellular domain (NECD) of the Drosophila Notch and human Notch1 receptors suitable for analysis by electron microscopy and three-dimensional (3D) image reconstruction. The resulting 3D density maps reveal that the NECD structure is conserved across species. We show that the NECD forms a dimer and adopts different yet defined conformations, and we identify the membrane-proximal region of the receptor and its ligand-binding site. Conclusions/Significance: Our results provide direct and unambiguous evidence that the NECD forms a dimer. Our studies further show that the NECD adopts at least three distinct conformations that are likely related to different functional states of the receptor. These findings open the way to now correlate mutations in the NECD with its oligomeric state and conformation

Attitudes of healthcare workers in U.S. hospitals regarding smallpox vaccination

BACKGROUND: The United States is implementing plans to immunize 500,000 hospital-based healthcare workers against smallpox. Vaccination is voluntary, and it is unknown what factors drive vaccine acceptance. This study's aims were to estimate the proportion of workers willing to accept vaccination and to identify factors likely to influence their decisions. METHODS: The survey was conducted among physicians, nurses, and others working primarily in emergency departments or intensive care units at 21 acute-care hospitals in 10 states during the two weeks before the U.S. national immunization program for healthcare workers was announced in December 2002. Of the questionnaires distributed, 1,165 were returned, for a response rate of 81%. The data were analyzed by logistic regression and were adjusted for clustering within hospital and for different number of responses per hospital, using generalized linear mixed models and SAS's NLMIXED procedure. RESULTS: Sixty-one percent of respondents said they would definitely or probably be vaccinated, while 39% were undecided or inclined against it. Fifty-three percent rated the risk of a bioterrorist attack using smallpox in the United States in the next two years as either intermediate or high. Forty-seven percent did not feel well-informed about the risks and benefits of vaccination. Principal concerns were adverse reactions and the risk of transmitting vaccinia. In multivariate analysis, four variables were associated with willingness to be vaccinated: perceived risk of an attack, self-assessed knowledge about smallpox vaccination, self-assessed previous smallpox vaccination status, and gender. CONCLUSIONS: The success of smallpox vaccination efforts will ultimately depend on the relative weight in people's minds of the risk of vaccine adverse events compared with the risk of being exposed to the disease. Although more than half of the respondents thought the likelihood of a bioterrorist smallpox attack was intermediate or high, less than 10% of the group slated for vaccination has actually accepted it at this time. Unless new information about the threat of a smallpox attack becomes available, healthcare workers' perceptions of the vaccine's risks will likely continue to drive their ongoing decisions about smallpox vaccination

Centers For Mendelian Genomics: a Decade of Facilitating Gene Discovery

PURPOSE: Mendelian disease genomic research has undergone a massive transformation over the past decade. With increasing availability of exome and genome sequencing, the role of Mendelian research has expanded beyond data collection, sequencing, and analysis to worldwide data sharing and collaboration. METHODS: Over the past 10 years, the National Institutes of Health-supported Centers for Mendelian Genomics (CMGs) have played a major role in this research and clinical evolution. RESULTS: We highlight the cumulative gene discoveries facilitated by the program, biomedical research leveraged by the approach, and the larger impact on the research community. Beyond generating a list of gene-phenotype relationships and participating in widespread data sharing, the CMGs have created resources, tools, and training for the larger community to foster understanding of genes and genome variation. The CMGs have participated in a wide range of data sharing activities, including deposition of all eligible CMG data into the Analysis, Visualization, and Informatics Lab-space (AnVIL), sharing candidate genes through the Matchmaker Exchange and the CMG website, and sharing variants in Genotypes to Mendelian Phenotypes (Geno2MP) and VariantMatcher. CONCLUSION: The work is far from complete; strengthening communication between research and clinical realms, continued development and sharing of knowledge and tools, and improving access to richly characterized data sets are all required to diagnose the remaining molecularly undiagnosed patients

Molecular Structure and Dimeric Organization of the Notch Extracellular Domain as Revealed by Electron Microscopy

Background: The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into the mechanism of the receptor as well as for potentially interfering with its function for therapeutic purposes. Methodology/Principal Findings: We used the Affinity Grid approach to prepare specimens of the Notch extracellular domain (NECD) of the Drosophila Notch and human Notch1 receptors suitable for analysis by electron microscopy and three-dimensional (3D) image reconstruction. The resulting 3D density maps reveal that the NECD structure is conserved across species. We show that the NECD forms a dimer and adopts different yet defined conformations, and we identify the membrane-proximal region of the receptor and its ligand-binding site. Conclusions/Significance: Our results provide direct and unambiguous evidence that the NECD forms a dimer. Our studies further show that the NECD adopts at least three distinct conformations that are likely related to different functional states of the receptor. These findings open the way to now correlate mutations in the NECD with its oligomeric state and conformation