SPICE steady state modelling of thermoelectric generators involving the Thomson effect

During operation thermoelectric generators (TEGs) are subject to the following thermal effects; Heat conduction according to Fourier's law, Joule heating, Peltier heating and Thomson heating. Many SPICE-based models exist for TEGs however in the vast majority of them the Thomson effect is neglected due to its relatively small size compared to the other effects, as well as the complexity that results from including the Thomson effect in the model. This paper seeks to present a model that governs the steady state performance of a TEG that includes the Thomson effect whilst limiting the complexity of the SPICE model. © 2011 IEEE

Fresh-Register Automata

What is a basic automata-theoretic model of computation with names and fresh-name generation? We introduce Fresh-Register Automata (FRA), a new class of automata which operate on an infinite alphabet of names and use a finite number of registers to store fresh names, and to compare incoming names with previously stored ones. These finite machines extend Kaminski and Francez’s Finite-Memory Automata by being able to recognise globally fresh inputs, that is, names fresh in the whole current run. We exam-ine the expressivity of FRA’s both from the aspect of accepted languages and of bisimulation equivalence. We establish primary properties and connections between automata of this kind, and an-swer key decidability questions. As a demonstrating example, we express the theory of the pi-calculus in FRA’s and characterise bisimulation equivalence by an appropriate, and decidable in the finitary case, notion in these automata

Not Alone: Tracing the Origins of Very Low Mass Stars and Brown Dwarfs Through Multiplicity Studies

The properties of multiple stellar systems have long provided important empirical constraints for star formation theories, enabling (along with several other lines of evidence) a concrete, qualitative picture of the birth and early evolution of normal stars. At very low masses (VLM; M <~ 0.1 M_sun), down to and below the hydrogen burning minimum mass, our understanding of formation processes is not as clear, with several competing theories now under consideration. One means of testing these theories is through the empirical characterization of VLM multiple systems. Here, we review the results of various VLM multiplicity studies to date. These systems can be generally characterized as closely separated (93% have projected separations Delta < 20 AU) and near equal-mass (77% have M_2/M_1 >= 0.8) occurring infrequently (perhaps 10-30%). Both the frequency and maximum separation of stellar and brown dwarf binaries steadily decrease for lower system masses, suggesting that VLM binary formation and/or evolution may be a mass-dependent process. There is evidence for a fairly rapid decline in the number of loosely-bound systems below ~0.3 M_sun, corresponding to a factor of 10-20 increase in the minimum binding energy of VLM binaries as compared to more massive stellar binaries. This wide-separation ``desert'' is present among both field (~1-5 Gyr) and older (> 100 Myr) cluster systems, while the youngest (<~10 Myr) VLM binaries, particularly those in nearby, low-density star forming regions, appear to have somewhat different systemic properties. We compare these empirical trends to predictions laid out by current formation theories, and outline future observational studies needed to probe the full parameter space of the lowest mass multiple systems.Comment: 16 pages, 7 figures, contributed chapter for Planets and Protostars V meeting (October 2005); full table of VLM binaries can be obtained at http://paperclip.as.arizona.edu/~nsiegler/VLM_binarie

Hyperfine-mediated gate-driven electron spin resonance

An all-electrical spin resonance effect in a GaAs few-electron double quantum dot is investigated experimentally and theoretically. The magnetic field dependence and absence of associated Rabi oscillations are consistent with a novel hyperfine mechanism. The resonant frequency is sensitive to the instantaneous hyperfine effective field, and the effect can be used to detect and create sizable nuclear polarizations. A device incorporating a micromagnet exhibits a magnetic field difference between dots, allowing electrons in either dot to be addressed selectively.Comment: related papers available at http://marcuslab.harvard.ed

Conditional operation of a spin qubit

We report coherent operation of a singlet-triplet qubit controlled by the arrangement of two electrons in an adjacent double quantum dot. The system we investigate consists of two pairs of capacitively coupled double quantum dots fabricated by electrostatic gates on the surface of a GaAs heterostructure. We extract the strength of the capacitive coupling between qubit and double quantum dot and show that the present geometry allows fast conditional gate operation, opening pathways to multi-qubit control and implementation of quantum algorithms with spin qubits.Comment: related papers here: http://marcuslab.harvard.ed

P09-15. Selection of higher avidity HLA-restricted T cell responses as a viral adaptation strategy

Loss of immune reactivity due to HIV mutational escape is well described. Data generated from a large population-based study (n>800) suggested that certain CD8 T cell epitopes are created as a result of HIV adaptation and are associated with enhanced viral replication. Here we sought to investigate the HLA-restricted T-cell responses associated with seven such adaptations

Discovery of a 66 mas Ultracool Binary with Laser Guide Star Adaptive Optics

We present the discovery of 2MASS J21321145+1341584AB as a closely separated (0.066") very low-mass field dwarf binary resolved in the near-infrared by the Keck II Telescope using laser guide star adaptive optics. Physical association is deduced from the angular proximity of the components and constraints on their common proper motion. We have obtained a near-infrared spectrum of the binary and find that it is best described by an L5+/-0.5 primary and an L7.5+/-0.5 secondary. Model-dependent masses predict that the two components straddle the hydrogen burning limit threshold with the primary likely stellar and the secondary likely substellar. The properties of this sytem - close projected separation (1.8+/-0.3 AU) and near unity mass ratio - are consistent with previous results for very low-mass field binaries. The relatively short estimated orbital period of this system (~7-12 yr) makes it a good target for dynamical mass measurements. Interestingly, the system's angular separation is the tightest yet for any very low-mass binary published from a ground-based telescope and is the tightest binary discovered with laser guide star adaptive optics to date.Comment: 10 pages, 3 figures; accepted for publication to A

Fitting ACE Structural Equation Models to Case-Control Family Data

Investigators interested in whether a disease aggregates in families often collect case-control family data, which consist of disease status and covariate information for families selected via case or control probands. Here, we focus on the use of case-control family data to investigate the relative contributions to the disease of additive genetic effects (A), shared family environment (C), and unique environment (E). To this end, we describe a ACE model for binary family data and then introduce an approach to fitting the model to case-control family data. The structural equation model, which has been described previously, combines a general-family extension of the classic ACE twin model with a (possibly covariate-specific) liability-threshold model for binary outcomes. Our likelihood-based approach to fitting involves conditioning on the proband’s disease status, as well as setting prevalence equal to a pre-specified value that can be estimated from the data themselves if necessary. Simulation experiments suggest that our approach to fitting yields approximately unbiased estimates of the A, C, and E variance components, provided that certain commonly-made assumptions hold. These assumptions include: the usual assumptions for the classic ACE and liability-threshold models; assumptions about shared family environment for relative pairs; and assumptions about the case-control family sampling, including single ascertainment. When our approach is used to fit the ACE model to Austrian case-control family data on depression, the resulting estimate of heritability is very similar to those from previous analyses of twin data

A New Zealand regional work-related sprains and strains surveillance, management and prevention programme: study protocol.

BACKGROUND: The impact and costs associated with work-related sprains and strains in New Zealand and globally are substantial and a major occupational and public health burden. In New Zealand around one-third of all sprains and strains workers compensation (ACC) claims (2019) are for back injuries, but shoulder and arm injuries are increasing at a faster rate than other sprain and strain injuries (ACC, 2020). A need exists for a change to current approaches to sprains and strains prevention, to more effectively manage this significant and persistent problem in workplaces. Designing out hazards is one of the most effective means of preventing occupational injuries and illnesses. This paper outlines the study protocol of the surveillance, management and prevention programme and describes the utilisation of prevention through design principles in the prevention of work-related sprains and strains in agriculture/horticulture/food production in the Hawkes Bay region of New Zealand. METHODS: This is a prospective mixed methods study incorporating the collection of quantitative data to describe the epidemiology of work related sprains and strains injuries presenting to the regional health centre (Hastings Health Centre) over a period of 24 months and qualitative data from participants presenting at the health centre to identify high risk industry sectors/ occupations/ workplaces and tasks and design, develop and apply prevention through design principles/ solutions/interventions to critical features of the work and work environment and undertake an outcome evaluation during the last 6 months of the project. DISCUSSION: The purpose of this project is to establish an epidemiological surveillance programme to assess the incidence and prevalence of work-related sprains and strains according to age, sex, industry sector and occupation to target efforts to prevent work-related sprains and strains, by applying prevention through design (PtD) principles in selected workplaces in agriculture. The collection of more detailed case, occupational and work history data from a sample of patients presenting at the HHC clinic will identify high risk industry sectors/occupations/workplaces and tasks. Assessment techniques will include comprehensive design, design thinking and human factors/ergonomics methodologies through co-design and participatory ergonomics techniques. The PtD solutions/ interventions implemented will be evaluated using a quasi-experimental design consisting of a pre-test/ post-test with-in subjects design with control groups that do not receive the intervention.Published onlin