'The world is full of big bad wolves': investigating the experimental therapeutic spaces of R.D. Laing and Aaron Esterson

In conjunction with the recent critical assessments of the life and work of R.D. Laing, this paper seeks to demonstrate what is revealed when Laing’s work on families and created spaces of mental health care are examined through a geographical lens. The paper begins with an exploration of Laing’s time at the Tavistock Clinic in London during the 1960s, and of the co-authored text with Aaron Esterson entitled, Sanity, Madness and the Family (1964). The study then seeks to demonstrate the importance Laing and his colleague placed on the time-space situatedness of patients and their worlds. Finally, an account is provided of Laing’s and Esterson’s spatial thinking in relation to their creation of both real and imagined spaces of therapeutic care

Asymmetry of jets, lobe size and spectral index in radio galaxies and quasars

We investigate the correlations between spectral index, jet side and extent of the radio lobes for a sample of nearby FRII radio galaxies. In Dennett-Thorpe et al. (1997) we studied a sample of quasars and found that the high surface brightness regions had flatter spectra on the jet side (explicable as a result of Doppler beaming) whilst the extended regions had spectral asymmetries dependent on lobe length. Unified schemes predict that asymmetries due to beaming will be much smaller in narrow-line radio galaxies than in quasars: we therefore investigate in a similar manner, a sample of radio galaxies with detected jets. We find that spectral asymmetries in these objects are uncorrelated with jet sidedness at all brightness levels, but depend on relative lobe volume. Our results are not in conflict with unified schemes, but suggest that the differences between the two samples are due primarily to power or redshift, rather than to orientation. We also show directly that hotspot spectra steepen as a function of radio power or redshift. Whilst a shift in observed frequency due to the redshift may account for some of the steepening, it cannot account for all of it, and a dependence on radio power is required.Comment: accepted for publication in MNRAS, 10 pages; typos/minor correctio

Multifrequency VLA observations of the FR I radio galaxy 3C 31: morphology, spectrum and magnetic field

We present high-quality VLA images of the FR I radio galaxy 3C 31 in the frequency range 1365 to 8440 MHz with angular resolutions from 0.25 to 40 arcsec. Our new images reveal complex, well resolved filamentary substructure in the radio jets and tails. We also use these images to explore the spectral structure of 3C 31 on large and small scales. We infer the apparent magnetic field structure by correcting for Faraday rotation. Some of the intensity substructure in the jets is clearly related to structure in their apparent magnetic field: there are arcs of emission where the degree of linear polarization increases, with the apparent magnetic field parallel to the ridges of the arcs. The spectral indices are significantly steeper (0.62) within 7 arcsec of the nucleus than between 7 and 50 arcsec (0.52 - 0.57). The spectra of the jet edges are also slightly flatter than the average for their surroundings. At larger distances, the jets are clearly delimited from surrounding larger-scale emission both by their flatter radio spectra and by sharp brightness gradients. The spectral index of 0.62 in the first 7 arcsec of 3C 31's jets is very close to that found in other FR I galaxies where their jets first brighten in the radio and where X-ray synchrotron emission is most prominent. Farther from the nucleus, where the spectra flatten, X-ray emission is fainter relative to the radio. The brightest X-ray emission from FR I jets is therefore not associated with the flattest radio spectra, but with a particle-acceleration process whose characteristic energy index is 2.24. The spectral flattening with distance from the nucleus occurs where our relativistic jet models require deceleration, and the flatter-spectra at the jet edges may be associated with transverse velocity shear. (Slightly abridged)Comment: 17 pages, 13 figures, accepted for publication in MNRA

Arsenic in soils and waters around the Kori Kollo gold mine on the Bolivian Altiplano: redox-induced speciation and mobilization

Mining activities in the Bolivian Altiplano have caused considerable negative environmental consequences on the water, soils, vegetation resources, biodiversity, and the atmosphere over the years. In this study, samples of soils, sediments, river water, water from drinking pools, and groundwater were collected from the area around the Kori Kollo gold mine, located near the city of Oruro on the Bolivian Altiplano to investigate the concentrations of arsenic (As) as an important contaminant associated with the mining activities in this area. Moreover, the redox-induced speciation, mobilization, and release dynamics, of As in soil/sediment samples was studied under controlled reducing and oxidizing conditions using an automated biogeochemical microcosm apparatus. The total As concentrations in the soils ranged between 10 and 81 mg kg-1 and exceeded the international trigger action values (10-65 mg kg-1) of As in agricultural soils. Arsenic concentrations (µg L-1) reached values up to 2,688, 952, and 300 in the groundwater, drinking pools, and surface water, respectively and exceeded the current WHO provisional guideline value of 10 µg L-1. The total dissolved concentrations of As varied from 368 to 3,130 µg L-1. The dissolved concentrations of As increased under oxidizing conditions and decreased under reducing conditions. Data of As speciation showed that the As (III) accounted from 0.0 to 79% of the total dissolved As and increased under reducing conditions, while the As (V) accounted from 21-100% of the total dissolved As and increased under oxidizing conditions. The results conclude that i) although the total concentrations of As in the soils around the mine are not very high, the concentrations of As in the waters were very high, 2) the concentrations of total dissolved As were very high which might indicate the high mobilization of As and support the anthropogenic source of As in theses soils, 3) the release and mobilization of As increased under oxidizing conditions as compared to the reducing conditions, and 4) the As (III) accounted values up to 79% of total dissolved As, which might increase the toxicity and risk of As in the soils and waters especially under reducing conditions. These results highlight the environment risk of As which might be a main reason for the gradual death of goats and cows, the biodiversity and the decline of fishing and agricultural sources in this area

Factors affecting metal mobilisation during oxidation of sulphidic, sandy wetland substrates

Most metals accumulate as sulphides under anoxic conditions in wetland substrates, reducing their bioavailability due to the solubility of metal sulphides. However, upon oxidation of these sulphides when the substrate is occasionally oxidised, metals can be released from the solid phase to the pore water or overlaying surface water. This release can be affected by the presence of carbonates, organic matter and clay. We compared changes of Cd, Cu and Zn mobility (CaCl2 extraction) during oxidation of a carbonate-rich and a carbonate-poor sulphidic, sandy wetland substrate. In addition, we studied how clay with low and high cation sorption capacity (bentonite and kaolinite, respectively) and organic matter (peat) can counteract Cd, Cu and Zn release during oxidation of both carbonate-rich and carbonate-poor sulphidic sediments. CaCl2-extractability of Cu, a measure for its availability, is low in both carbonate-poor and carbonate-rich substrates, whereas its variability is high. The availability of Cd and Zn is much higher and increases when peat is supplied to carbonate-poor substrates. A strong reduction of Cd and Zn extractability is observed when clay is added to carbonate-poor substrates. This reduction depends on the clay type. Most observations could be explained taking into account pH differences between treatments, with kaolinite resulting in a lower pH in comparison to bentonite. These pH differences affect the presence and characteristics of dissolved organic carbon and the metal speciation, which in turns affects the interaction of metals with the solid soil phase. In carbonate-rich substrates, Cd and Zn availability is lower and the effects of peat and clay amendment are less clear. The latter can also be attributed to the high pH and lack of pH differences between treatments

Study protocol for a cluster-randomized controlled trial of an NCD access to medicines initative: Evaluation of Novartis Access in Kenya

INTRODUCTION: Novartis recently launched Novartis Access, an initiative to provide a basket of reduced price medicines for non-communicable diseases (NCDs) to be sold through the public and private nonprofit sectors in programme countries. This study will evaluate the impact of Novartis Access on the availability and price of NCD medicines at health facilities and households in Kenya, the first country to receive the programme. METHODS: This study will be a cluster randomised controlled trial. 8 counties in Kenya will be randomly assigned to the intervention or control group using a covariate constrained randomisation method to maximise balance on demographic and health characteristics. In intervention counties, public and private non-profit health facilities will be able to order Novartis Access NCD medicines from the Mission for Essential Drugs and Supplies (MEDS). Data will be collected from a random sample of 384 health facilities and 800 households at baseline, midline after 1-year of intervention, and end-line after 2 years. Quarterly surveillance data will also be collected from health facilities and a subsample of households through phone-based interviews. Households will be eligible if at least one resident has been previously diagnosed and prescribed a medicine for an NCD addressed by Novartis Access, including hypertension and diabetes. The primary outcomes will be availability and price of NCD medicines at health facilities, and availability, price, and expenditures on NCD medicines at households. Impacts will be estimated using intention-to-treat analysis. ETHICS AND DISSEMINATION: This protocol was approved by the Institutional Review Boards at Strathmore University and at Boston University. Informed consent will be obtained from all participants at the start of the trial. The findings of the trial will be disseminated through peer-reviewed journals, international conferences, and meetings and events organised with local stakeholders

The XMM-Newton Detection of Diffuse Inverse Compton X-rays from Lobes of the FR-II Radio Galaxy 3C98

The XMM-Newton observation of the nearby FR-II radio galaxy 3C 98 is reported. In two exposures on the target, faint diffuse X-ray emission associated with the radio lobes was significantly detected, together with a bright X-ray active nucleus, of which the 2 -- 10 keV intrinsic luminosity is (4 -- 8) \times 10^{42} erg s-1. The EPIC spectra of the northern and southern lobes are reproduced by a single power law model modified by the Galactic absorption, with a photon index of 2.2-0.5+0.6 and 1.7-0.6+0.7 respectively. These indices are consistent with that of the radio synchrotron spectrum, 1.73 +- 0.01 The luminosity of the northern and southern lobes are measured to be 8.3-2.6+3.3 \times 10^{40} erg s-1 and 9.2-4.3+5.7 \times 10^{40} erg s-1, respectively, in the 0.7 -- 7 keV range. The diffuse X-ray emission is interpreted as an inverse-Compton emission, produced when the synchrotron-emitting energetic electrons in the lobes scatter off the cosmic microwave background photons. The magnetic field in the lobes is calculated to be about 1.7 \mu G, which is about 2.5 times lower than the value estimated under the minimum energy condition. The energy density of the electrons is inferred to exceed that in the magnetic fields by a factor of 40 -- 50.Comment: 23 pages, 7 figures. Accepted for publication in the Astrophysical Journa

Polarization in the prompt emission of gamma-ray bursts and their afterglows

Synchrotron is considered the dominant emission mechanism in the production of gamma-ray burst photons in the prompt as well as in the afterglow phase. Polarization is a characteristic feature of synchrotron and its study can reveal a wealth of information on the properties of the magnetic field and of the energy distribution in gamma-ray burst jets. In this paper I will review the theory and observations of gamma-ray bursts polarization. While the theory is well established, observations have prove difficult to perform, due to the weakness of the signal. The discriminating power of polarization observations, however, cannot be overestimated.Comment: 16 pages, 9 figures, accepted for publication in the New Journal of Physics focus issue on Gamma Ray Burst