The worlds a stage

The theme of the article comments upon ‘reality' as a fabricated space for deceit and when one’s attention is drawn toward the physical break down of ‘the façade’. This specific attempt at concealment will reference The Truman Show and the Fallen Spotlight scene as a technical mishap that becomes the catalyst of suspicion. Further reflection will touch upon how the entertainment industry is exploring immersive sensory experiences that enhance a fictitious version of reality and the alignment with our contemporary preoccupation with ‘reality TV’. The conclusion will speculate on Truman’s existential plight and the profound implications that fiction maybe the only reality we know

The Printed reality exhibition curated by Paul Laidler

Journal article in the The California Printmaker: The Journal of the California Society of Printmakers. The invention and subsequent development of the printed image has changed the way in which we learn, see and describe the world around us. Our preoccupation with viewing the world through its image has created an environment of two-dimensional projections unfolding from three-dimensional beginnings. Within the Printed Reality group the interplay between image and object is not a seamless transition but one of artifice, theatre. Here the recorded image functions as a backdrop, a stage prop positioned and presented in such a manner that we are readerly accepting of its fictional role. The performance emanates through the recording of edges and folds, casting both shadows and omitting reflections from an external world, a reality not of our own but somewhat more representative of our own.The Printed Reality Exhibition presents photographic images by seven different artists within a gallery instillation setting. The exhibition was conceived as a format for considering the relationship between print and the Internet in the era of Photography 2.0. The overlapping of the electronic image and printed presentation in The Printed Reality exhibition draws upon further associations with the use of digital platforms as a means to disseminate physical artefacts within museums, galleries and educational institutions.The Printed Reality is a collection of imagesgenerated by users of the photo-sharing website Flickr.Curated by Paul Laidler, the almost five hundred photographsin this virtual gallery document the very real waysthat we interact with the printed image in our daily lives.An exhibition of projected images from The PrintedReality was presented during the 2009 Impact conferenceat the University of West England

Revisiting Richard Hamilton’s typo-topography of Marcel Duchamp’s Large Glass

The production of fine art prints has a longstanding relationship with the collaborative print studio, where artists work together with master printers to realize and produce printed artworks. The collaboration between artist and print studio has predominantly been one of facilitation, where the artist is able to access specialist equipment and technical expertise with the tools, materials and operations of a particular print studio. What this involves and what the relationships are has varied between print studios and even between the master printers of a studio. This article will discuss the production of an inkjet printed edition for the artists Richard Hamilton using the collaborative print studio model within a University setting

Collaborative print studio

The collaborative print studio has had profound impact upon the production and realisation of some of the most innovative prints within the discipline of fine art printmaking. Historically an artist with little understanding of the print process or access to print facilities could seek the technical knowledge and craft sensibilities from a master printer. In some instances these unique collaborative pursuits redefined production methods and push the boundaries of what was previously thought possible. These historical precedents have been established through mechanical modes of production and have contributed to defining the roles, expectations, production, publication and artisanship of the collaborative print studio. Over the last 20 years we have seen new digital tools and processes enter the traditional domain of the collaborative print studio. These developments, have to some degree, brought in to question the role of the traditional print studio in the digital age. For example, we may consider a shift from manual dexterity to automated systems or the ubiquitous nature of digital resources and their impact upon previous associations with specialist tools and facilities

Collaborative digital and wide format printing: Methods and considerations for the artist and master printer

This thesis investigates the collaborative production of fine art digital prints for artists,a process which is used by many contemporary practitioners including RichardHamilton and Damien Hirst. Digital print as a fine art process has emerged over the last twenty years, and as yet, there is no in depth evidence on the collaborative endeavour and production process which is central to the digital Master Printer’s role.The investigation first establishes the historical context and significance of the Master and Printer in traditional printmaking, and the more recent development of the digital print studio and the digital print pioneers of the 1990s. A series of seven artists’ case studies in the context of the collaborative digital print studio are then offered to demonstrate the working process. The analysis of these proposes a best practice model for Master Printers working with contemporary artists to produce high quality, fine art, wide format inkjet digital prints.The study also compares production methods at the cutting-edge digital facility of the Rijksakademie in The Netherlands, to assess the validity of the practices proposed through a facility closest to the study’s research base at the CFPR’s digital studio. The comparative study also explored the expanding digital production process and the role of the Master Printer. Evolving production processes are also considered in this study as a response to the advancement of digital print technology alongside a practical exploration of what actually constitutes a digital print in this rapidly expanding field of fine art printmaking.This study aims to reveal the inner workings of the digital collaborative process between the artist and Master Printer, and appraise the digital Master Printer’s role.It offers a set of best practice methods for the digital Master Printer developed from this research. The study also considers how the digital print, and the digital print studio may evolve in line with current and future developments in new technologies

Determination of the glycoforms of human chorionic gonadotropin b-core fragment by matrix-assisted laser desoption/ionisation time of flight mass spectrometry

Background: Metabolism of human chorionic gonadotropin (hCG) in the serum and kidney yields the terminal urinary product hCG ß-core fragment (hCGßcf), comprising two disulfide-linked peptides (ß6-ß40 and ß55-ß92) of which one (ß6-ß40) retains truncated N-linked sugars. Hyperglycosylated hCGßcf may indicate choriocarcinoma or Down syndrome, but the glycosylation profile of hCGßcf has not been thoroughly evaluated. Methods: hCGßcf, purified from pregnancy urine, was reduced by "on-target" dithiothreitol (DTT) reduction and analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The mass ([M+H]+) of the primary sequence of the glycosylated peptide ß6-ß40 was subtracted from the m/z values of the discrete peaks observed to give the masses of the carbohydrate moieties. Carbohydrate structure was predicted by sequentially subtracting the masses of the monosaccharide residues corresponding to N-linked carbohydrates of the hCG ß-subunit reported in the literature. Results: Mass spectra of hCGßcf revealed a broad triple peak at m/z 8700–11300. After reduction, the triple peak was replaced by a discrete set of peaks between m/z 4156 and 6354. A peak at m/z 4156.8 corresponded to the nonglycosylated peptide (ß55-ß92). The remaining nine peaks indicated that urinary hCGßcf comprises a set of glycoforms smaller and larger than the trimannosyl core. Conclusions: hCGßcf comprises a wider set of glycoforms than reported previously. Peaks of highest mass indicate evidence of hyperglycosylated carbohydrate moieties. The data support previous reports that hCGßcf oligosaccharides lack sialic acid and galactose residues. No indication was found of a ß6-ß40 peptide that was entirely devoid of carbohydrate

Remote Sensing of Arctic Vegetation: Relations between the NDVI, Spatial Resolution and Vegetation Cover on Boothia Peninsula, Nunavut

Arctic tundra environments are thought to be particularly sensitive to changes in climate, whereby alterations in ecosystem functioning are likely to be expressed through shifts in vegetation phenology, species composition, and net ecosystem productivity (NEP). Remote sensing has shown potential as a tool to quantify and monitor biophysical variables over space and through time. This study explores the relationship between the normalized difference vegetation index (NDVI) and percent-vegetation cover in a tundra environment, where variations in soil moisture, exposed soil, and gravel till have significant influence on spectral response, and hence, on the characterization of vegetation communities. IKONOS multispectral data (4 m spatial resolution) and Landsat 7 ETM+ data (30 m spatial resolution) were collected for a study area in the Lord Lindsay River watershed on Boothia Peninsula, Nunavut. In conjunction with image acquisition, percent cover data were collected for twelve 100 m × 100 m study plots to determine vegetation community composition. Strong correlations were found for NDVI values calculated with surface and satellite sensors, across the sample plots. In addition, results suggest that percent cover is highly correlated with the NDVI, thereby indicating strong potential for modeling percent cover variations over the region. These percent cover variations are closely related to moisture regime, particularly in areas of high moisture (e.g., water-tracks). These results are important given that improved mapping of Arctic vegetation and associated biophysical variables is needed to monitor environmental change.On croit que les environnements de la toundra arctique sont particulièrement sensibles aux changements climatiques, en ce sens que toute altération du fonctionnement de l’écosystème est susceptible d’être exprimée dans le réarrangement de la phénologie de la végétation, de la composition des espèces et de la productivité nette de l’écosystème (PNÉ). La télédétection s’avère un outil efficace de quantification et de surveillance des variables biophysiques dans le temps et dans l’espace. Cette étude explore la relation entre l’indice d’activité végétale et le pourcentage de couverture végétale en milieu de toundra, où les variations propres à l’humidité du sol, au sol exposé et au till de gravier ont une influence considérable sur la réponse spectrale et, par conséquent, sur la caractérisation des communautés végétales. Des données multispectrales IKONOS (résolution spatiale de 4 m) et des données ETM+ de Landsat 7 (résolution spatiale de 30 m) ont été recueillies pour une zone d’étude visée par la ligne de partage des eaux à la hauteur de la rivière Lord Lindsay, dans la péninsule de Boothia, au Nunavut. De concert avec l’acquisition d’images, les données relatives au pourcentage de couverture ont été recueillies pour douze terrains d’étude de 100 m sur 100 m dans le but de déterminer la composition de la communauté végétale. De fortes corrélations ont été dénotées dans le cas des valeurs de l’indice d’activité végétale calculées à l’aide de détecteurs de surface et de détecteurs satellisés et ce, à l’échelle des terrains ayant servi d’échantillon. Par ailleurs, les résultats laissent entendre que le pourcentage de couverture est hautement corrélé avec l’indice d’activité végétale, ce qui indique une forte possibilité de modélisation des variations de pourcentage de couverture dans la région. Ces variations du pourcentage de couverture sont étroitement liées au régime d’humidité, particulièrement dans les régions où l’humidité est élevée (comme les traces d’eau). Ces résultats revêtent de l’importance étant donné qu’il y a lieu d’améliorer le mappage de la végétation arctique et les variables biophysiques connexes afin de surveiller la modification de l’environnement

Fel d 1–derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: A randomized, placebo-controlled study

BackgroundAllergic rhinoconjunctivitis is an increasingly common source of morbidity, with sensitivity to cats accounting for 10% to 15% of disease burden. Allergy to cats is also a major risk factor for the development of asthma.ObjectivesWe sought to probe the persistence of the treatment effect of a novel Fel d 1–derived peptide antigen desensitization (Cat-PAD) 1 year after the start of treatment in subjects with cat allergy–induced rhinoconjunctivitis after standardized allergen challenge.MethodsIn a randomized, double-blind, placebo-controlled, parallel-group clinical trial, subjects attended an environmental exposure chamber in which they were exposed to cat allergen before and after treatment with 2 different regimens of Cat-PAD over a 3-month period. Clinical efficacy was assessed as a change in total rhinoconjunctivitis symptom scores 18 to 22 weeks and 50 to 54 weeks after the start of treatment.ResultsTreatment with Cat-PAD showed greater efficacy with 4 administrations of a 6-nmol dose 4 weeks apart than with 8 administrations of a 3-nmol dose 2 weeks apart. The treatment effect of 6 nmol persisted 1 year after the start of treatment and was significantly different from that of 3 nmol (P = .0342) and placebo (P = .0104). The treatment effect was apparent on both nasal and ocular symptoms at 1 year.ConclusionsA short course of Cat-PAD improves the ocular and nasal components of rhinoconjunctivitis symptoms in subjects with cat allergy, with the treatment effect persisting 1 year after the start of treatment

Effect of tilt angle on the performance of a thin-film photovoltaic system

Solar energy is among the cleanest and most sustainable ways to enhance electrical supply's resiliency and reliability for domestic and industrial use. A Photovoltaic (PV) system is the most effective way of capturing solar energy. Long-term warranty, low-cost maintenance, and vast resource availability, solar power generation has an advantage over other approaches. Thin-film technology PV cells are a new kind of solar cell that offers an efficient technique of generating electricity from sunlight. The thin-film PV technology (FFMAT-10, Renovagen, UK) used in this study can supply 0.9 to 1.6 kW of energy to the fast-fold energy hub. The hub’s system status and configuration display battery power input, battery’s state of charge, thin-film PV power and AC power output. Two fast-fold mats (with a surface area of 25.3 m2) were connected to the energy hub. Increasing energy demand coupled with frequent power outages, and inaccessibility of electricity in rural areas necessitates the usage of PV systems at their best performance level. The study objective, therefore, sought to assess the effect of tilt angle on the performance of the thin-film PV system. The study was conducted at Kimicha in Kirinyaga County Kenya, and Juja, Kenya at tilt angles between 0o to 30o. The results indicated that the mean peak PV power for Kimicha was 347.8±231.9 W at 5o and 517.7± 131.3 W at 15ofor Juja. The maximum solar radiation during the study period was 1086.4 ±211.4 W/m2 for Juja and 973.5±219.93 W/m2 for Kimicha. From the study, it was realized that an optimal tilt angle yields optimum solar radiation that translates to maximum power production. Even though the study was conducted in two different regions, it may be applied to any other geographical location. The outcome of the study aids in acquiring self-sustaining power in the most remote locations where electricity is scarce as well as improving energy security

How dark the sky: the JWST backgrounds

We describe the sources of stray light and thermal background that affect JWST observations; report actual backgrounds as measured from commissioning and early science observations; compare those background levels to pre-launch predictions; estimate the impact of the backgrounds on science performance; and explore how the backgrounds probe the achieved configuration of the deployed observatory. We find the observatory is limited by the irreducible astrophysical backgrounds, rather than scattered stray light and thermal self-emission, for all wavelengths $\lambda < 12.5$ micron, thus meeting the level 1 requirement. This result was not assured given the open architecture and thermal challenges of JWST, and is the result of meticulous attention to stray light and thermal issues in the design, construction, integration, and test phases. From background considerations alone, JWST will require less integration time in the near-infrared compared to a system that just met the stray light requirements; as such, JWST will be even more powerful than expected for deep imaging at 1--5 micron. In the mid-infrared, the measured thermal backgrounds closely match pre-launch predictions. The background near 10 micron is slightly higher than predicted before launch, but the impact on observations is mitigated by the excellent throughput of MIRI, such that instrument sensitivity will be as good as expected pre-launch. These measured background levels are fully compatible with JWST's science goals and the Cycle 1 science program currently underway.Comment: Submitted to the "JWST Overview" special issue of PAS