31 research outputs found
Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice
The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice
Spontaneous decay in the presence of dispersing and absorbing bodies: general theory and application to a spherical cavity
A formalism for studying spontaneous decay of an excited two-level atom in
the presence of dispersing and absorbing dielectric bodies is developed. An
integral equation, which is suitable for numerical solution, is derived for the
atomic upper-state-probability amplitude. The emission pattern and the power
spectrum of the emitted light are expressed in terms of the Green tensor of the
dielectric-matter formation including absorption and dispersion. The theory is
applied to the spontaneous decay of an excited atom at the center of a
three-layered spherical cavity, with the cavity wall being modeled by a
band-gap dielectric of Lorentz type. Both weak coupling and strong coupling are
studied, the latter with special emphasis on the cases where the atomic
transition is (i) in the normal-dispersion zone near the medium resonance and
(ii) in the anomalous-dispersion zone associated with the band gap. In a
single-resonance approximation, conditions of the appearance of Rabi
oscillations and closed solutions to the evolution of the atomic state
population are derived, which are in good agreement with the exact numerical
results.Comment: 12 pages, 6 figures, typos fixed, 1 figure adde
Three-dimensional quantization of the electromagnetic field in dispersive and absorbing inhomogeneous dielectrics
A quantization scheme for the phenomenological Maxwell theory of the full
electromagnetic field in an inhomogeneous three-dimensional, dispersive and
absorbing dielectric medium is developed. The classical Maxwell equations with
spatially varying and Kramers-Kronig consistent permittivity are regarded as
operator-valued field equations, introducing additional current- and
charge-density operator fields in order to take into account the noise
associated with the dissipation in the medium. It is shown that the equal-time
commutation relations between the fundamental electromagnetic fields
and and the potentials and in the Coulomb gauge
can be expressed in terms of the Green tensor of the classical problem. From
the Green tensors for bulk material and an inhomogeneous medium consisting of
two bulk dielectrics with a common planar interface it is explicitly proven
that the well-known equal-time commutation relations of QED are preserved
Moho depth of the northern Vietnam and Gulf of Tonkin from 3D inverse interpretation of gravity anomaly data
A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus
Dengue is a rapidly emerging, mosquito-borne viral infection, with an estimated 400 million infections occurring annually. To gain insight into dengue immunity, we characterized 145 human monoclonal antibodies (mAbs) and identified a previously unknown epitope, the envelope dimer epitope (EDE), that bridges two envelope protein subunits that make up the 90 repeating dimers on the mature virion. The mAbs to EDE were broadly reactive across the dengue serocomplex and fully neutralized virus produced in either insect cells or primary human cells, with 50% neutralization in the low picomolar range. Our results provide a path to a subunit vaccine against dengue virus and have implications for the design and monitoring of future vaccine trials in which the induction of antibody to the EDE should be prioritized