Scattering Lens Resolves sub-100 nm Structures with Visible Light

The smallest structures that conventional lenses are able to optically resolve are of the order of 200 nm. We introduce a new type of lens that exploits multiple scattering of light to generate a scanning nano-sized optical focus. With an experimental realization of this lens in gallium phosphide we have succeeded to image gold nanoparticles at 97 nm optical resolution. Our work is the first lens that provides a resolution in the nanometer regime at visible wavelengths.Comment: 4 pages, 3 figure

Non-Imaging Speckle Interferometry forHigh Speed Nanometer-Scale Position Detection

We experimentally demonstrate a non-imaging approach to displacement measurement for complex scattering materials. By spatially controlling the wave front of the light that incidents on the material we concentrate the scattered light in a focus on a designated position. This wave front acts as an unique optical fingerprint that enables precise position detection of the illuminated material by simply measuring the intensity in the focus. By combining two optical fingerprints we demonstrate position detection along one dimension with a displacement resolution of 2.1 nm. As our approach does not require an image of the scattered field, it is possible to employ fast non-imaging detectors to enable high-speed position detection of scattering materials.Comment: 4 pages, 3 figure

Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination

Among opportunistically pathogenic filamentous fungi of the Aspergillus genus, Aspergillus fumigatus stands out as a drastically more prevalent cause of infection than others. Utilizing the zebrafish embryo model, we applied a combination of non-invasive real-time imaging and genetic approaches to compare the infectious development of A. fumigatus with that of the less pathogenic A. niger. We found that both species evoke similar immune cell migratory responses, but A. fumigatus is more efficiently phagocytized than A. niger. Though efficiently phagocytized, A. fumigatus conidia retains the ability to germinate and form hyphae from inside macrophages leading to serious infection even at relatively low infectious burdens. By contrast, A. niger appears to rely on extracellular germination, and rapid hyphal growth to establish infection. Despite these differences in the mechanism of infection between the species, galactofuranose mutant strains of both A. fumigatus and A. niger display attenuated pathogenesis. However, deficiency in this cell wall component has a stronger impact on A. niger, which is dependent on rapid extracellular hyphal growth. In conclusion, we uncover differences in the interaction of the two fungal species with innate immune cells, noticeable from very early stages of infection, which drive a divergence in their route to establishing infections

Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination

Among opportunistically pathogenic filamentous fungi of the Aspergillus genus, Aspergillus fumigatus stands out as a drastically more prevalent cause of infection than others. Utilizing the zebrafish embryo model, we applied a combination of non-invasive real-time imaging and genetic approaches to compare the infectious development of A. fumigatus with that of the less pathogenic A. niger. We found that both species evoke similar immune cell migratory responses, but A. fumigatus is more efficiently phagocytized than A. niger. Though efficiently phagocytized, A. fumigatus conidia retains the ability to germinate and form hyphae from inside macrophages leading to serious infection even at relatively low infectious burdens. By contrast, A. niger appears to rely on extracellular germination, and rapid hyphal growth to establish infection. Despite these differences in the mechanism of infection between the species, galactofuranose mutant strains of both A. fumigatus and A. niger display attenuated pathogenesis. However, deficiency in this cell wall component has a stronger impact on A. niger, which is dependent on rapid extracellular hyphal growth. In conclusion, we uncover differences in the interaction of the two fungal species with innate immune cells, noticeable from very early stages of infection, which drive a divergence in their route to establishing infections

Inhibited spontaneous emission of quantum dots observed in a 3D photonic band gap

We present time-resolved emission experiments of semiconductor quantum dots in silicon 3D inverse-woodpile photonic band gap crystals. A systematic study is made of crystals with a range of pore radii to tune the band gap relative to the emission frequency. The decay rates averaged over all dipole orientations are inhibited by a factor of 10 in the photonic band gap and enhanced up to 2? outside the gap, in agreement with theory. We discuss the effects of spatial inhomogeneity, nonradiative decay, and transition dipole orientations on the observed inhibition in the band gap.Comment: 5 figures, update author lis

Probing the eigenfunction fractality with a stop watch

We study numerically the distribution of scattering phases ${\cal P}(\Phi)$ and of Wigner delay times ${\cal P}(\tau_W)$ for the power-law banded random matrix (PBRM) model at criticality with one channel attached to it. We find that ${\cal P}(\Phi)$ is insensitive to the position of the channel and undergoes a transition towards uniformity as the bandwidth $b$ of the PBRM model increases. The inverse moments of Wigner delay times scale as $\sim L^{- q D_{q+1}}$, where $D_q$ are the multifractal dimensions of the eigenfunctions of the corresponding closed system and $L$ is the system size. The latter scaling law is sensitive to the position of the channel.Comment: 5 pages, 4 figure

Exact Quantum Monte Carlo Process for the Statistics of Discrete Systems

We introduce an exact Monte Carlo approach to the statistics of discrete quantum systems which does not rely on the standard fragmentation of the imaginary time, or any small parameter. The method deals with discrete objects, kinks, representing virtual transitions at different moments of time. The global statistics of kinks is reproduced by explicit local procedures, the key one being based on the exact solution for the biased two-level system.Comment: 4 pages, latex, no figures, English translation of the paper

Diffusion and Localization of Cold Atoms in 3D Optical Speckle

In this work we re-formulate and solve the self-consistent theory for localization to a Bose-Einstein condensate expanding in a 3D optical speckle. The long-range nature of the fluctuations in the potential energy, treated in the self-consistent Born approximation, make the scattering strongly velocity dependent, and its consequences for mobility edge and fraction of localized atoms have been investigated numerically.Comment: 8 pages, 11 figure

Photon Localization in Resonant Media

We report measurements of microwave transmission over the first five Mie resonances of alumina spheres randomly positioned in a waveguide. Though precipitous drops in transmission and sharp peaks in the photon transit time are found near all resonances, measurements of transmission fluctuations show that localization occurs only in a narrow frequency window above the first resonance. There the drop in the photon density of states is found to be more pronounced than the fall in the photon transit time, leading to a minimum in the Thouless number.Comment: To appear in PRL; 5 pages, including 5 figure

A new numerical approach to Anderson (de)localization

We develop a new approach for the Anderson localization problem. The implementation of this method yields strong numerical evidence leading to a (surprising to many) conjecture: The two dimensional discrete random Schroedinger operator with small disorder allows states that are dynamically delocalized with positive probability. This approach is based on a recent result by Abakumov-Liaw-Poltoratski which is rooted in the study of spectral behavior under rank-one perturbations, and states that every non-zero vector is almost surely cyclic for the singular part of the operator. The numerical work presented is rather simplistic compared to other numerical approaches in the field. Further, this method eliminates effects due to boundary conditions. While we carried out the numerical experiment almost exclusively in the case of the two dimensional discrete random Schroedinger operator, we include the setup for the general class of Anderson models called Anderson-type Hamiltonians. We track the location of the energy when a wave packet initially located at the origin is evolved according to the discrete random Schroedinger operator. This method does not provide new insight on the energy regimes for which diffusion occurs.Comment: 15 pages, 8 figure