Connaissances et perceptions de la religion et du phénomène de la radicalisation chez les étudiant(e)s du collégial

Comprend des références bibliographiquesDiffusé avec l'aimable autorisation des auteurs. Le document original est également accessible en ligne : http://cefir.cegepmontpetit.ca/2018/05/16/connaissances-et-perceptions-de-la-religion-et-du-phenomene-de-la-radicalisation-chez-les-etudiantes-du-collegial-2018

Incidence, predictive factors and haemodynamic consequences of acute stent recoil following transcatheter aortic valve implantation with a balloon-expandable valve

Aims: The elastic behaviour (acute recoil) of a valve prosthesis stent following transcatheter aortic valve implantation (TAVI) is unknown. This study sought to determine the occurrence, severity, predictive factors and haemodynamic consequences of acute recoil following TAVI. Methods and results : A prospective angiographic analysis of the stent frame dimensions in 111 consecutive patients who underwent TAVI with a balloon-expandable valve (36 Edwards SAPIEN; 75 SAPIEN XT) was performed. Acute recoil was defined as the difference between minimal lumen diameter (MLD) at full balloon expansion and immediately after balloon deflation. MLD during balloon inflation was significantly larger than MLD after balloon deflation (23.40±2.31 mm vs. 22.29±2.21 mm, p<0.001), which represented an absolute and percent decrease in stent dimension of 1.10±0.40 mm and 4.70±1.76%, respectively. In the multivariate analysis, the predictors of larger recoil were a higher prosthesis/annulus ratio (r²=0.0624, p=0.015) and the SAPIEN XT prosthesis (r²=0.1276, p=0.001). No significant changes in haemodynamic performance were observed at discharge and follow-up in patients with larger recoil. Conclusions : TAVI with a balloon-expandable valve was systematically associated with a certain degree of valve stent recoil after balloon deflation. A higher degree of valve oversizing and the SAPIEN XT prosthesis predicted a larger degree of stent recoil

Moderate to severe acute pain disturbs motor cortex intracortical inhibition and facilitation in orthopedic trauma patients : a TMS study

Objective Primary motor (M1) cortical excitability alterations are involved in the development and maintenance of chronic pain. Less is known about M1-cortical excitability implications in the acute phase of an orthopedic trauma. This study aims to assess acute M1-cortical excitability in patients with an isolated upper limb fracture (IULF) in relation to pain intensity. Methods Eighty-four (56 IULF patients <14 days post-trauma and 28 healthy controls). IULF patients were divided into two subgroups according to pain intensity (mild versus moderate to severe pain). A single transcranial magnetic stimulation (TMS) session was performed over M1 to compare groups on resting motor threshold (rMT), short-intracortical inhibition (SICI), intracortical facilitation (ICF), and long-interval cortical inhibition (LICI). Results Reduced SICI and ICF were found in IULF patients with moderate to severe pain, whereas mild pain was not associated with M1 alterations. Age, sex, and time since the accident had no influence on TMS measures. Discussion These findings show altered M1 in the context of acute moderate to severe pain, suggesting early signs of altered GABAergic inhibitory and glutamatergic facilitatory activities

Quantum cosmology in the models of 2d and 4d dilatonic supergravity with WZ matter

We consider N=1 two-dimensional (2d) dilatonic supergravity (SG), 2d dilatonic SG obtained by dimensional reduction from N=1 four-dimensional (4d) SG, N=2 2d dilatonic SG and string-inspired 4d dilatonic SG. For all the theories, the corresponding action on a bosonic background is constructed and the interaction with $N$ (dilatonic) Wess-Zumino (WZ) multiplets is presented. Working in the large-N approximation, it is enough to consider the trace anomaly induced effective action due to dilaton-coupled conformal matter as a quantum correction (for 2d models s-waves approximation is additionally used). The equations of motion for all such models with quantum corrections are written in a form convenient for numerical analysis. Their solutions are numerically investigated for 2d and 4d Friedmann-Robertson-Walker (FRW) or 4d Kantowski-Sacks Universes with a time-dependent dilaton via exponential dilaton coupling. The evolution of the corresponding quantum cosmological models is given for different choices of initial conditions and theory parameters. In most cases we find quantum singular Universes. Nevertheless, there are examples of Universe non-singular at early times. Hence, it looks unlikely that quantum matter back reaction on dilatonic background (at least in large $N$ approximation) may really help to solve the singularity problem.Comment: LaTeX file of the text (36 pages) and 3 ps files of 14 figures, few misprints are corrected and references adde

Reduced phase space formalism for spherically symmetric geometry with a massive dust shell

We perform a Hamiltonian reduction of spherically symmetric Einstein gravity with a thin dust shell of positive rest mass. Three spatial topologies are considered: Euclidean (R^3), Kruskal (S^2 x R), and the spatial topology of a diametrically identified Kruskal (RP^3 - {a point at infinity}). For the Kruskal and RP^3 topologies the reduced phase space is four-dimensional, with one canonical pair associated with the shell and the other with the geometry; the latter pair disappears if one prescribes the value of the Schwarzschild mass at an asymptopia or at a throat. For the Euclidean topology the reduced phase space is necessarily two-dimensional, with only the canonical pair associated with the shell surviving. A time-reparametrization on a two-dimensional phase space is introduced and used to bring the shell Hamiltonians to a simpler (and known) form associated with the proper time of the shell. An alternative reparametrization yields a square-root Hamiltonian that generalizes the Hamiltonian of a test shell in Minkowski space with respect to Minkowski time. Quantization is briefly discussed. The discrete mass spectrum that characterizes natural minisuperspace quantizations of vacuum wormholes and RP^3-geons appears to persist as the geometrical part of the mass spectrum when the additional matter degree of freedom is added.Comment: 36 pages, REVTeX v3.1 with amsfonts. (References updated; minor typos corrected.

Genes Involved in the Balance between Neuronal Survival and Death during Inflammation

Glucocorticoids are potent regulators of the innate immune response, and alteration in this inhibitory feedback has detrimental consequences for the neural tissue. This study profiled and investigated functionally candidate genes mediating this switch between cell survival and death during an acute inflammatory reaction subsequent to the absence of glucocorticoid signaling. Oligonucleotide microarray analysis revealed that following lipopolysaccharide (LPS) intracerebral administration at striatum level, more modulated genes presented transcription impairment than exacerbation upon glucocorticoid receptor blockage. Among impaired genes we identified ceruloplasmin (Cp), which plays a key role in iron metabolism and is implicated in a neurodegenative disease. Microglial and endothelial induction of Cp is a natural neuroprotective mechanism during inflammation, because Cp-deficient mice exhibited increased iron accumulation and demyelination when exposed to LPS and neurovascular reactivity to pneumococcal meningitis. This study has identified genes that can play a critical role in programming the innate immune response, helping to clarify the mechanisms leading to protection or damage during inflammatory conditions in the CNS