70 research outputs found

    Is the perceived impact of disciplinary procedures on medical doctors’ professional practice associated with working in an open culture and feeling supported?:A questionnaire among medical doctors in the Netherlands who have been disciplined

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    Introduction Disciplinary procedures can have a negative impact on the professional functioning of medical doctors. In this questionnaire study, doctors’ experience with open culture and support during a disciplinary procedure is studied to determine whether open culture and support are associated with perceived changes in the professional practice of doctors. Methods All doctors who received a warning or a reprimand from the Dutch Medical Disciplinary Board between July 2012 and August 2016 were invited to fill in a 60-item questionnaire concerning open culture, perceived support during the disciplinary procedure and the impact of the procedure on professional functioning as reported by doctors themselves. The response rate was 43% (n=294). Results A majority of doctors perceive their work environment as a safe environment in which to talk about and report incidents (71.2% agreed). Respondents felt supported by a lawyer or legal representative and colleagues (92.8% and 89.2%, respectively). The disciplinary procedure had effects on professional practice. Legal support and support from a professional confidant and a professional association were associated with fewer perceived changes to professional practice. Conclusion Our study shows that doctors who had been disciplined perceive their working environment as open. Doctors felt supported by lawyers and/or legal representatives and colleagues. Legal support was associated with less of a perceived impact on doctors’ professional practice

    Peptidoglycan hydrolases-potential weapons against Staphylococcus aureus

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    The RESOLVE project: a multi-physics experiment with a temporary dense seismic array on the Argentière Glacier, French Alps

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    International audienceRecent work in the field of cryo-seismology demonstrates that high frequency (>1 Hz) seismic waves provide key constraints on a wide range of glacier processes such as basal friction, surface crevassing or subglacial water flow. Establishing quantitative links between the seismic signal and the processes of interest however requires detailed characterization of the wavefield, which at high frequencies necessitates the deployment of large and particularly dense seismic arrays. Although dense seismic array monitoring has recently become increasingly common in geophysics, its application to glaciated environments remains limited. Here we present a dense seismic array experiment made of 98 3-component seismic stations continuously recording during 35 days in early spring 2018 on the Argentière Glacier, French Alps. The seismic dataset is supplemented with a wide range of complementary observations obtained from ground penetrating radar, drone imagery, GNSS positioning and in-situ measurements of basal glacier sliding velocities and subglacial water discharge. We present first results through conducting spectral analysis, template matching, matched-field processing and eikonal wave tomography. We report enhanced spatial resolution on basal stick slip and englacial fracturing sources as well as novel constraints on the heterogeneous nature of the noise field generated by subglacial water flow and on the link between crevasse properties and englacial seismic velocities. We outline in which ways further work using this dataset could help tackle key remaining questions in the field

    Epidemiological cut-off values for Vibrio anguillarum MIC and disc diffusion data generated by standardised methods

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    This work aims to generate the data needed to set epidemiological cut-off values for minimum inhibitory concentration (MIC) and disc-diffusion zone measurements of Vibrio anguillarum. A total of 261 unique isolates were tested, applying standard methods specifying incubation at 28 degrees C for 24-28 h. Aggregated MIC distributions for a total of 247 isolates were determined in 9 laboratories for 11 agents. Data aggregations of the disc zone for the 10 agents analysed contained between 157 and 218 observations made by 4 to 7 laboratories. Acceptable ranges for quality control (QC) reference strains were available for 7 agents and the related multi-laboratory aggregated data were censored, excluding the data of a laboratory that failed to meet QC requirements. Statistical methods were applied to calculate epidemiological cut-off values. Cut-off values for MIC data were calculated for florfenicol (<= 1 mu g ml-1), gentamicin (<= 4 mu g ml-1), oxytetracycline (<= 0.25 mu g ml-1) and trimethoprim/sulfamethoxazole (<= 0.125/2.38 mu g ml-1). The cut-off values for disc zone data were calculated for enrofloxacin (>= 29 mm), florfenicol (>= 27 mm), gentamicin (>= 19 mm), oxolinic acid (>= 24 mm), oxytetracycline (>= 24 mm) and trimethoprim/sulfamethoxazole (>= 26 mm). MIC and disc-diffusion zone data for the other agents where not supported by QC, thus yielding only provisional cut-off values (meropenem, ceftazidime). Regardless of whether QC is available, some of the aggregated MIC distributions (enrofloxacin, oxolinic acid), disc zone (sulfamethoxazole), and MIC and disc-diffusion distributions (ampicillin, chloramphenicol) did not meet the statistical requirements. The data produced will be submitted to the Clinical Laboratory Standards Institute for their consideration in setting international consensus epidemiological cut-off values
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