178 research outputs found
A new species of Clinostomum
http://deepblue.lib.umich.edu/bitstream/2027.42/56522/1/OP083.pd
Culture, Courage and Change: The experiences of a Te Kotahitanga facilitation team
This thesis explores the experiences of the Te Kotahitanga facilitation team in one of the 12 Phase 3 Te Kotahitanga schools between 2003 and 2006. The collaborative story through which those experiences are shared includes the voices of the Lead facilitator, the two co-principals, and an RTLB/facilitator. This thesis begins by seeking to understand the historical impact of culturally located discourses of colonisation on the lives of the indigenous Māori people in New Zealand. From within a platform of Māori theorising it also considers Kaupapa Māori research methodologies and explores Māori people’s aspirations for self determination (tino rangatiratanga). It then considers the principles and practices of engaging as a bicultural partnership to improve educational outcomes for Māori students. Through a discussion of the facilitation team's experiences of learning about a culturally responsive pedagogy of relations through the development and support of culturally responsive contexts for learning, three important themes emerge: culture, courage and change. The impact of deficit theorising and pathologising practices on the culture of Maori students and their teachers is examined. The courage required of the Te Kotahitanga principals and facilitators to challenge and disrupt the assumptions that underpinned the historical status quo in this school and the importance of remaining steadfast in response to the dissonance and resistance that these change processes created is then discussed. Finally, this thesis highlights both the interdependent nature of the change required and the power of the collective in creating change; change within ourselves, within our classrooms and within our schools and communities for the benefit of Māori students, and of all students
Two new parasitic flatworms
http://deepblue.lib.umich.edu/bitstream/2027.42/56532/1/OP093.pd
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Extent and Determinants of Error in Doctors' Prognoses in Terminally Ill Patients: Prospective Cohort Study
Objective: To describe doctors' prognostic accuracy in terminally ill patients and to evaluate the determinants of that accuracy.
Design: Prospective cohort study.
Setting: Five outpatient hospice programmes in Chicago.
Participants: 343 doctors provided survival estimates for 468 terminally ill patients at the time of hospice referral.
Main outcome measures: Patients' estimated and actual survival.
Results: Median survival was 24 days. Only 20% (92/468) of predictions were accurate (within 33% of actual survival); 63% (295/468) were overoptimistic and 17% (81/468) were overpessimistic. Overall, doctors overestimated survival by a factor of 5.3. Few patient or doctor characteristics were associated with prognostic accuracy. Male patients were 58% less likely to have overpessimistic predictions. Non-oncology medical specialists were 326% more likely than general internists to make overpessimistic predictions. Doctors in the upper quartile of practice experience were the most accurate. As duration of doctor-patient relationship increased and time since last contact decreased, prognostic accuracy decreased.
Conclusion: Doctors are inaccurate in their prognoses for terminally ill patients and the error is systematically optimistic. The inaccuracy is, in general, not restricted to certain kinds of doctors or patients. These phenomena may be adversely affecting the quality of care given to patients near the end of life.Sociolog
The Library Under the Sun: Knowledge and Vanity in Umberto Eco’s The Name of the Rose
Umberto Eco’s debut novel The Name of the Rose is so saturated with theoretical conversations and allusions that it can be read as a work of critical theory almost as much as it can be read as the wonderful detective novel that so many people have enjoyed. This thesis approaches the novel accordingly, engaging with the theoretical questions and ideas presented in the novel and evaluating them based on a biblical worldview. The central theoretical questions in the novel revolve around what can be known and how. Many critics have argued that the novel answers these questions of epistemology in a very pessimistic postmodern light, concluding that human knowledge is at best extremely limited and fragmented. This conclusion is warranted by the text, but given the open nature of the work, the same evidence can be seen as pointing to a much more stable understanding of human knowledge when read with the background of a Christian worldview – a background which the novel itself invites given its setting and cast of characters. The key element that invites this reading is the novel’s presentation of comedy. This thesis concludes that the novel ultimately presents a view of knowledge that is compatible with the view presented in Ecclesiastes where man’s knowledge is limited but enough for him to rest in with joy
Research Revisited: Cognitive Effects of Greek Affiliation in College: Additional Evidence
Previous research found broad based negative effects of fraternity/sorority affiliation on standardized measures of cognitive development after one year of college. Following the same sample, and employing essentially the same research design and analytic model, the present study found that the negative effects of fraternity/sorority affiliation were much less pronounced during the second or third years of college
RNA-seq: primary cells, cell lines and heat stress
Transcriptome analysis by RNA-seq has emerged as a high-throughput, cost-effective means to evaluate the expression pattern of genes in organisms. Unlike other methods, such as microarrays or quantitative PCR, RNA-seq is a target free method that permits analysis of essentially any RNA that can be amplified from a cell or tissue. At its most basic, RNA-seq can determine individual gene expression levels by counting the number of times a particular transcript was found in the sequence data. Transcript levels can be compared across multiple samples to identify differentially expressed genes and infer differences in biological states between the samples. We have used this approach to examine gene expression patterns in chicken and human cells, with particular interest in determining response to heat stress
Most Colorectal Cancer Survivors Live a Large Proportion of Their Remaining Life in Good Health
Purpose Colorectal cancer (CRC) diagnosis reduces life expectancy and decreases patients’ well-being. We sought to assess the determinants of health and functional status and estimate the proportion of remaining life that CRC survivors would spend in good health. Methods Using Sullivan method, healthy life expectancy was calculated based on survival data of 14,849 CRC survivors within a population-based cancer registry in southern Netherlands and quality of life information among a random sample of these survivors (n = 1,291). Results: Overall, albeit short life expectancy (LE at age 50 = 12 years for males and 13 years for females), most CRC survivors spent a large proportion of their remaining life in good health (74 and 77 %, for males and females, respectively). Long-term survivors may expect to live a normal life span (LE at age 50 = 30 years) and spent a large proportion of the remaining life in good health (78 %). In distinction, those with stage IV CRC had less than 2 years to live and spent more than half of their remaining life in poor health. Conclusions: Most CRC patients may expect no compromise on living a healthy life, underlining the importance of early detection. On the other hand, the high proportion of non-healthy years among stage IV CRC survivors confirms the importance of early detection and palliative care. Electronic supplementary material The online version of this article (doi:10.1007/s10552-012-0010-2) contains supplementary material, which is available to authorized users
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