6,739 research outputs found
Non-Gaussianity from two right-handed sneutrino curvaton decays
In this paper, we consider the effect of two right-handed sneutrino curvaton
decays and investigate the parameter space. We compare the difference of the
result between single- and two-curvaton cases. We find one Yukawa coupling of
the right-handed snetrinos can be as large as while the
other one is much smaller which is consistent with the idea that only one
generation of the neutrino mass may be much smaller than others. When the
curvatons decay, we assume both of them subdominate the energy density of the
universe. We find that, unlike a single curvaton case, here a small or
negative, as well as a large can be generated.Comment: 9 pages, 6 figures, 1 table, to appear in General Relativity and
Gravitatio
Order-Preserving Abstractive Summarization for Spoken Content Based on Connectionist Temporal Classification
Connectionist temporal classification (CTC) is a powerful approach for
sequence-to-sequence learning, and has been popularly used in speech
recognition. The central ideas of CTC include adding a label "blank" during
training. With this mechanism, CTC eliminates the need of segment alignment,
and hence has been applied to various sequence-to-sequence learning problems.
In this work, we applied CTC to abstractive summarization for spoken content.
The "blank" in this case implies the corresponding input data are less
important or noisy; thus it can be ignored. This approach was shown to
outperform the existing methods in term of ROUGE scores over Chinese Gigaword
and MATBN corpora. This approach also has the nice property that the ordering
of words or characters in the input documents can be better preserved in the
generated summaries.Comment: Accepted by Interspeech 201
One-Dimensional Nature of Pairing and Superconductivity at the LaAlO/SrTiO Interface
We examine superconductivity in LaAlO/SrTiO channels in which the
channel width transitions from the 1D to 2D regime. The superconducting
critical current is independent of the channel width and increases
approximately linearly with the number of parallel channels. Signatures of
electron pairing outside of the superconducting phase are also independent of
channel width. Collectively, these results indicate that electron pairing and
superconductivity exist at the boundary of these channels and are absent within
the interior region of the channels. The intrinsic 1D nature of
superconductivity at the LaAlO/SrTiO interface imposes strong physical
constraints on possible electron pairing mechanisms.Comment: 13 pages, 5 figure
Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia
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Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates.
Tumor metastasis into the central nervous system (CNS) and lymph nodes (LNs) is a major obstacle for effective therapies. Therapeutic monoclonal antibodies (mAb) have revolutionized tumor treatment; however, their efficacy for treating metastatic tumors-particularly, CNS and LN metastases-is poor due to inefficient penetration into the CNS and LNs following intravenous injection. We recently reported an effective delivery of mAb to the CNS by encapsulating the anti-CD20 mAb rituximab (RTX) within a thin shell of polymer that contains the analogs of choline and acetylcholine receptors. This encapsulated RTX, denoted as n-RTX, eliminated lymphoma cells systemically in a xenografted humanized mouse model using an immunodeficient mouse as a recipient of human hematopoietic stem/progenitor cells and fetal thymus more effectively than native RTX; importantly, n-RTX showed notable anti-tumor effect on CNS metastases which is unable to show by native RTX. As an important step toward future clinical translation of this technology, we further analyzed the properties of n-RTX in immunocompetent animals, rats, and non-human primates (NHPs). Our results show that a single intravenous injection of n-RTX resulted in 10-fold greater levels in the CNS and 2-3-fold greater levels in the LNs of RTX, respectively, than the injection of native RTX in both rats and NHPs. In addition, we demonstrate the enhanced delivery and efficient B-cell depletion in lymphoid organs of NHPs with n-RTX. Moreover, detailed hematological analysis and liver enzyme activity tests indicate n-RTX treatment is safe in NHPs. As this nanocapsule platform can be universally applied to other therapeutic mAbs, it holds great promise for extending mAb therapy to poorly accessible body compartments
Comments on SUSY inflation models on the brane
In this paper we consider a class of inflation models on the brane where the
dominant part of the inflaton scalar potential does not depend on the inflaton
field value during inflation. In particular, we consider supernatural
inflation, its hilltop version, A-term inflation, and supersymmetric (SUSY) D-
and F-term hybrid inflation on the brane. We show that the parameter space can
be broadened, the inflation scale generally can be lowered, and still possible
to have the spectral index .Comment: 7 page
Ring-Like Solitons in Plasmonic Fiber Waveguide Composed of Metal-Dielectric Multilayers
We design a plasmonic fiber waveguide (PFW) composed of coaxial cylindrical
metal-dielectric multilayers in nanoscale, and constitute the corresponding
dynamical equations describing the modes of propagation in the PFW with the
Kerr nonlinearity in the dielectric layers. The physics is connected to the
discrete matrix nonlinear Schr\"{o}dinger equations, from which the highly
confined ring-like solitons in scale of subwavelength are found both for the
visible light and the near-infrared light in the self-defocusing condition.
Moreover, the confinement could be further improved when increasing the
intensity of the input light due to the cylindrical symmetry of the PFW, which
means both the width and the radius of the ring are reduced.Comment: 4 figures, submitte
The absence of the Kerr black hole in the Ho\v{r}ava-Lifshitz gravity
We show that the Kerr metric does not exist as a fully rotating black hole
solution to the modified Ho\v{r}ava-Lifshitz (HL) gravity with
and case. We perform it by showing that the Kerr metric does not
satisfy full equations derived from the modified HL gravity.Comment: 35 pages, no figure
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