32,486 research outputs found
Atopic Dermatitis Host and Environment Model: Revisiting Therapeutic Options
Atopic Dermatitis affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of its triggers and includes emollients, topical steroids and calcineurin inhibitors among others. Immunological dysfunction can be addressed broadly with systemic immunosupressors and specifically with monoclonal antibodies. Dupilumab, which targets IL-4 and IL-13 was granted approval for treatment of moderate-to-severe AD. Biologics targeting IgE/Th2 pathways may have its role in patients with overlapping AD and asthma. Psychological distress can exacerbate symptoms and is associated with increased severity of AD. Environmental triggers, such as, allergens can be addressed in selected cases with allergic immunotherapy. In this paper, we discuss AD treatment and propose a new step-by-step approach aiming at maintaining disease control and improving quality of life.info:eu-repo/semantics/publishedVersio
A dynamical point of view of Quantum Information: entropy and pressure
Quantum Information is a new area of research which has been growing rapidly
since last decade. This topic is very close to potential applications to the so
called Quantum Computer. In our point of view it makes sense to develop a more
"dynamical point of view" of this theory. We want to consider the concepts of
entropy and pressure for "stationary systems" acting on density matrices which
generalize the usual ones in Ergodic Theory (in the sense of the Thermodynamic
Formalism of R. Bowen, Y. Sinai and D. Ruelle). We consider the operator
acting on density matrices over a finite
-dimensional complex Hilbert space where and , are
operators in this Hilbert space. is not a linear operator. In
some sense this operator is a version of an Iterated Function System (IFS).
Namely, the , , play the role of the
inverse branches (acting on the configuration space of density matrices )
and the play the role of the weights one can consider on the IFS. We
suppose that for all we have that . A
family determines a Quantum Iterated Function System
(QIFS) , $\mathcal{F}_W=\{\mathcal{M}_N,F_i,W_i\}_{i=1,...,
k}.
Is there a propeller neutron star in Cas?
Cas is the prototype of a small population of B0-B1.5 III-V
classical Be (cBe) stars that emit anomalous and hard X-rays with a unique
array of properties. Cas is known to host, like other cBe stars, a
decretion disk and also a low mass companion. Recently Postnov et al. have
posited that this companion is a magnetized rapidly spinning neutron star that
deflects direct gravitational accretion from a stellar/disk wind via the
"propeller mechanism." These authors state that the key X-ray observations are
"remarkably well produced" in this scenario. We reexamine this mechanism in
detail and conclude that there are a number of fatal objections in its
application to the Cas case. Among other considerations these issues
include the prediction under the propeller scenario of a much smaller
population of Cas stars than is observed and the lack of allowance for
observed correlations of X-ray and UV and/or optical properties over a variety
of timescales.Comment: 9 page
A dynamical point of view of Quantum Information: Wigner measures
We analyze a known version of the discrete Wigner function and some
connections with Quantum Iterated Funcion Systems. This paper is a follow up of
"A dynamical point of view of Quantum Information: entropy and pressure" by the
same authors
MCMC Bayesian Estimation in FIEGARCH Models
Bayesian inference for fractionally integrated exponential generalized
autoregressive conditional heteroskedastic (FIEGARCH) models using Markov Chain
Monte Carlo (MCMC) methods is described. A simulation study is presented to
access the performance of the procedure, under the presence of long-memory in
the volatility. Samples from FIEGARCH processes are obtained upon considering
the generalized error distribution (GED) for the innovation process. Different
values for the tail-thickness parameter \nu are considered covering both
scenarios, innovation processes with lighter (\nu2) tails
than the Gaussian distribution (\nu=2). A sensitivity analysis is performed by
considering different prior density functions and by integrating (or not) the
knowledge on the true parameter values to select the hyperparameter values
Murcha bacteriana ou murchadeira: uma inimiga do tomateiro em climas quentes.
bitstream/item/103071/1/cot-67.pd
Boas práticas de campo: um guia para produzir batatas sadias.
bitstream/CNPH-2009/32846/1/cot_34.pd
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