Midwest Roadside Safety Facility Expansion for Enhanced Research Capabilities

As Civil Engineering students, this group was tasked with designing and proposing an engineering solution to a real-world problem. In this case, the Midwest Roadside Safety Facility in Lincoln, Nebraska was looking for a planned proposal to add an additional building to their property for the purpose of additional research and office space. The group decided on the name Zana Engineering – Zana translating to “highly educated” in Kurmanji – to function as the organization responsible for creating this proposal and presentation. Zana Engineering designed this plan on several key factors, most significantly utility, affordability, safety, sustainability, functionality, longevity, and the possibility of future expansion. In order to fully analyze the scope of this project, the team utilized various site and soil profiles, maps, and multiple design manuals. Additionally, the team utilized AutoCAD 3D and Revit software to create the proposed designs. The team found that the ideal solution was to create a three-story multifunctional complex with a basement. The design incorporates design and research space for graduate students, office space for employees and faculty, a viewing deck for crash testing, and additional storage space. The building is located on the Northwest corner of the Lincoln Airport, with additional open space to the North and West of the proposed location to allow for future expansion. The total cost of the project was estimated to be $23,960,550 completed in roughly 18 months

Time-dependent mode structure for Lyapunov vectors as a collective movement in quasi-one-dimensional systems

Time dependent mode structure for the Lyapunov vectors associated with the stepwise structure of the Lyapunov spectra and its relation to the momentum auto-correlation function are discussed in quasi-one-dimensional many-hard-disk systems. We demonstrate mode structures (Lyapunov modes) for all components of the Lyapunov vectors, which include the longitudinal and transverse components of their spatial and momentum parts, and their phase relations are specified. These mode structures are suggested from the form of the Lyapunov vectors corresponding to the zero-Lyapunov exponents. Spatial node structures of these modes are explained by the reflection properties of the hard-walls used in the models. Our main interest is the time-oscillating behavior of Lyapunov modes. It is shown that the largest time-oscillating period of the Lyapunov modes is twice as long as the time-oscillating period of the longitudinal momentum auto-correlation function. This relation is satisfied irrespective of the particle number and boundary conditions. A simple explanation for this relation is given based on the form of the Lyapunov vector.Comment: 39 pages, 21 figures, Manuscript including the figures of better quality is available from http://www.phys.unsw.edu.au/~gary/Research.htm

Neonatal jaundice and its management: knowledge, attitude and practice of community health workers in Nigeria

BACKGROUND: Neonatal jaundice (NNJ) is still a leading cause of preventable brain damage, physical and mental handicap, and early death among infants in many communities. Greater awareness is needed among all health workers. The objective of the study was to assess the knowledge of primary health care workers about the description, causes, effective treatment, and sequelae of NNJ. METHODS: The setting was a local government area i.e. an administrative district within the south-western part of Nigeria. Community health workers in this area were interviewed by means of a self-administered questionnaire which focused on awareness and knowledge of neonatal jaundice and its causes, treatment and complications. RESULTS: Sixty-six community health workers participated in the survey and male-to-female ratio was 1:5. Their work experience averaged 13.5 (SD 12.7) years. Only 51.5% of the respondents gave a correct definition of NNJ. 75.8 % knew how to examine for this condition while 84.9 % knew at least two of its major causes in our environment. Also, only 54.5 % had adequate knowledge of effective treatment namely, phototherapy and exchange blood transfusion. Rather than referring affected babies to hospitals for proper management, 13.4 %, 10.4 % and 3 % of the participants would treat with ineffective drugs, natural phototherapy and herbal remedies respectively. None of the participants knew any effective means of prevention. CONCLUSION: Primary health care workers may have inadequate knowledge and misconceptions on NNJ which must be addressed concertedly before the impact of the condition on child health and well-being can be significantly reduced. We recommend regular training workshops and seminars for this purpose

The Effect of Ambient Air Pollution during Early Pregnancy on Fetal Ultrasonic Measurements during Mid-Pregnancy

BACKGROUND: Over the past decade there has been mounting evidence that ambient air pollution during pregnancy influences fetal growth. OBJECTIVES: This study was designed to examine possible associations between fetal ultrasonic measurements collected from 15,623 scans (13–26 weeks gestation) and ambient air pollution during early pregnancy. METHODS: We calculated mothers ’ average monthly exposures over the first 4 months of pregnancy for the following pollutants: particulate matter < 10 µm aerodynamic diameter (PM10), ozone, nitrogen dioxide, and sulfur dioxide. We examined associations with fetal femur length (FL), biparietal diameter (BPD), head circumference (HC), and abdominal circumference (AC). Final analyses included scans from only those women within 2 km of an air pollution monitoring site. We controlled for long-term trend, season, temperature, gestation, mother’s age, socioeconomic status, and fetal sex. RESULTS: A reduction in fetal AC was associated with O3 during days 31–60 [–1.42 mm; 95 % confidence interval (CI), –2.74 to –0.09], SO2 during days 61–90 (–1.67 mm; 95 % CI, –2.94 to –0.40), and PM10 during days 91–120 (–0.78 mm; 95 % CI, –1.49 to –0.08). Other results showed a reduction in BPD (–0.68 mm; 95 % CI, –1.09 to –0.27) associated with SO2 during days 0–30, a reduction in HC (–1.02 mm; 95 % CI, –1.78 to –0.26) associated with PM10 during days 91–120, and a reduction in FL associated with PM10 during days 0–30 (–0.28 mm; 95 % CI, –0.48 to –0.08) and 91–120 (–0.23; 95 % CI, –0.42 to –0.04). CONCLUSION: We found strong effects of ambient air pollution on ultrasound measures. Future research, including more individually detailed data, is needed to confirm our results. KEY WORDS: air pollution, fetal growth, pregnancy, temperature, ultrasound. Environ Health Perspect 116:362–369 (2008). doi:10.1289/ehp.10720 available vi

Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection.

Ebolaviruses pose significant public health problems due to their high lethality, unpredictable emergence, and localization to the poorest areas of the world. In addition to implementation of standard public health control procedures, a number of experimental human vaccines are being explored as a further means for outbreak control. Recombinant cytomegalovirus (CMV)-based vectors are a novel vaccine platform that have been shown to induce substantial levels of durable, but primarily T-cell-biased responses against the encoded heterologous target antigen. Herein, we demonstrate the ability of rhesus CMV (RhCMV) expressing Ebola virus (EBOV) glycoprotein (GP) to provide protective immunity to rhesus macaques against lethal EBOV challenge. Surprisingly, vaccination was associated with high levels of GP-specific antibodies, but with no detectable GP-directed cellular immunity

Noninvasive Assessment of Coronary Artery Disease in Women: What’s Next?

Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has helped to clarify our understanding of some of the sex-specific factors, which are important in detecting CAD. In women, the detection and evaluation of physiologically significant CAD is challenging, especially given that traditional tests designed to detect focal areas of coronary artery stenosis are less sensitive and specific in female patients who have a lower prevalence of obstructive coronary disease, greater burden of symptoms, and a high atherosclerotic burden. In this article, we review the available evidence on the role of contemporary cardiovascular imaging techniques in evaluating ischemic heart disease in women

Ethnic Inequalities in Psychological Distress : A Population Data Linkage Study on the Pacific Island of Guåhån/Guam

Psychological distress and mental illness has been found to be elevated in migrant groups living in sovereign countries, as well as for indigenous people living under colonial or administrative rule. The north Pacific island of Guam is unusual in its ethnic composition as it has no majority ethnic group, has a large indigenous population and remains a territory of the U.S. This study aimed to identify ethnic differences in self-reported psychological distress between the main ethnic groups on Guam. The study uses a cross sectional design with data linkage methodology, drawing on the Guam Census and the Behavioral Risk Factor Surveillance System health survey for Guam. The results showed that the native Chamorro population had worse self-reported psychological distress (defined as a ‘mental health condition or emotional problem’) than White/Caucasians (OR 2.09, 95% CI 1.52–2.87), particularly for severe distress (OR 3.61, 95% CI 1.33–2.77). This relationship persisted even after adjusting for a wide range of socio-demographic and economic factors (OR 2.58, 95% CI 1.15–5.76). Other Pacific Islanders also had higher psychological distress compared to White/Caucasians, but this association was largely explained by the adjusted factors. The findings are discussed in terms of social and economic disadvantage for Pacific Island peoples on Guam, as well as the impact of colonial administration, disaffection, and lack of autonomy for the Chamorro of Guam. Recommendations are made to improve psychiatric treatment for these groups by considering wider socio-political factors in assessment and treatment, as well as broader implications for the national dialogue on self-determination.Peer reviewe

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

Times Cited: 13

Phenomenological Implications of Deflected Mirage Mediation: Comparison with Mirage Mediation

We compare the collider phenomenology of mirage mediation and deflected mirage mediation, which are two recently proposed "mixed" supersymmetry breaking scenarios motivated from string compactifications. The scenarios differ in that deflected mirage mediation includes contributions from gauge mediation in addition to the contributions from gravity mediation and anomaly mediation also present in mirage mediation. The threshold effects from gauge mediation can drastically alter the low energy spectrum from that of pure mirage mediation models, resulting in some cases in a squeezed gaugino spectrum and a gluino that is much lighter than other colored superpartners. We provide several benchmark deflected mirage mediation models and construct model lines as a function of the gauge mediation contributions, and discuss their discovery potential at the LHC.Comment: 29 pages, 9 figure