998 research outputs found

    The Effect of Adsorbent Geometry and Surface Chemistry on HPLC Retention

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    Evaluating the Determinants of Young Runners' Continuance Intentions toward Wearable Devices

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    Running has gained popularity as a fitness activity in China, with a growing number of young runners utilizing wearable devices to monitor their running routines and engage in quantified self-practices. The continuous evolution of wearable devices in terms of products and services has expanded the choices available to young runners. Therefore, there is a need to analyze the factors influencing the continuance intention of young runners, providing insights into how to promote the sustained growth of these products or services in the market. This study is grounded in the Technology Acceptance Model and the Theory of Planned Behavior, with an extension incorporating the quantified self to explore the impact of users' continuance intentions to use wearable devices. A survey was conducted among 468 young runners who already used wearable devices, and the data collected were analyzed using PLS-SEM. The results indicate that perceived usefulness and attitudes from the Technology Acceptance Model positively influence intentions for continued use. Additionally, subjective norms according to the Theory of Planned Behavior positively influence continuance use intentions. However, perceived behavioral control does not have a significant effect on continuance use intentions. Conversely, the Quantified-Self positively influences continuance use intentions and partially mediates the relationship between perceived usefulness and continuance use intentions. This research has several theoretical implications for the Theory of Planned Behavior, the Technology Acceptance Model, and the Quantified-Self research construct. Moreover, this study has practical implications for practitioners concerning the adoption and acceptance of wearable devices by young people. This approach enables practitioners to target and implement precise strategies to meet the current demands of the young runner market. Doi: 10.28991/HIJ-2023-04-04-02 Full Text: PD

    Design of 3D graphic editor

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    In this report, the design of a 3D graphic editor is provided with object-oriented technology and OpenGL GLUT framework. The functionalities and features in the system of this project contain documenting 3D graphic objects, dynamically creating multiple windows and subwindows, and manipulating OpenGL features, such as, lighting, colors, solid and wire mesh states. A hierarchical data structure is built to enable import and export assembled object data. The application of building graphic objects shows that the system performs its functionalities

    Thermal stability of high temperature Pb-free solder interconnect characterised by in-situ electron microscopy

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    The present investigation aimed to use in-situ heating experiment in a transmission electron microscope (TEM) to live characterize the thermal stability of a Cu/Ni-W-P interlayer/ZnAl solder interconnect. It demonstrated the TEM was able to detect live intermetallic compounds (IMCs) growth during heating. In addition, stress building up was evidenced by the progressive evolving of the dislocations at the interface between NiW-P interlayer and the ZnAl Solder. However, due to the μm to nm scale of specimens' dimensions required for electron microscopy, the sample preparation and data interpretation remains a challenge

    Effects of Xinwei granule on expression levels of cyclin D1 and its upstream genes in gastric intraepithelial neoplasia tissues

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    Purpose: To explore the effects of Xinwei granule (XWG) on low-grade gastric intraepithelial neoplasia (LGIN) and the underlying mechanisms. Methods: To establish LGIN model, Wistar rats were treated with N-methyl-N'-nitrosoguanidine for 3 months. LGIN model rats were randomly grouped into five groups (n = 15), viz, negative control (NC), normal saline (NS) group, Xinwei granule (XWG) group, Weifuchun tablet (WFCT) group, and vatacoenayme tablet (VT) group. Normal rats (n = 17) served as negative control. Histological evaluation of gastric mucosa was undertaken using hematoxylin and eosin staining. Quantitative realtime polymerase chain reaction (qRT-PCR), western blot, and immunohistochemical assays were performed to determine mRNA expressions, protein expression, and the distribution of cyclin D1, kruppel-like factor 4 (KLF4), and p21-WAF1-CIP1, respectively. Results: Compared with LGIN group, the body weight of the rats increased in XWG, WFCT, and VT groups. The pathological characteristics of LGIN group were alleviated by XWG, WFCT and VT treatments. The positive expression of cyclin D1 was enhanced in LGIN group, but reduced in XWG, WFCT and VT groups. The expression levels of KLF4 and p21-WAF1-CIP1, upstream regulators of cyclin D1 reduced in LGIN groups. However, administration of XWG, WFCT and VT strengthened the expressions of KLF4 and p21-WAF1-CIP1. More importantly, the protective effects of XWG against LGIN were superior to those of WFCT and VT. Conclusion: Xinwei granules alleviate LGIN in vivo by inhibiting cyclin D1 expression and enhancing KLF4 and p21-WAF1-CIP1 expression

    Multimodal Sentiment Analysis: A Survey

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    Multimodal sentiment analysis has become an important research area in the field of artificial intelligence. With the latest advances in deep learning, this technology has reached new heights. It has great potential for both application and research, making it a popular research topic. This review provides an overview of the definition, background, and development of multimodal sentiment analysis. It also covers recent datasets and advanced models, emphasizing the challenges and future prospects of this technology. Finally, it looks ahead to future research directions. It should be noted that this review provides constructive suggestions for promising research directions and building better performing multimodal sentiment analysis models, which can help researchers in this field.Comment: It needs to be returned for major modification

    Purifikacija i svojstva kolagenolitičke proteaze proizvedene s pomoću Bacillus cereus MBL13

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    A novel collagenase-producing bacterium has been isolated and identified as Bacillus cereus MBL13. From the culture supernatant of B. cereus MBL13 grown on bone collagen as the sole carbon and nitrogen source, an extracellular protease with novel property of hydrolyzing waste animal bones was purified. The molecular mass of the purified collagenolytic protease was estimated to be (38.0±1.5) kDa. As determined by amino acid analysis, it had high contents of asparagine, lysine and serine. The optimum temperature and pH for the collagenase activity were 40 °C and pH=8.0, respectively. The results of the effects of some metal ions, inhibitors and protein substrates suggested that the purified collagenolytic protease is a member of the metalloproteases. Type I collagen (the typical collagen in animal bone) was used as the substrate for determination of Michaelis-Menten kinetics. The obtained Km value was (1.31±0.05) g/L and the corresponding vmax value was (12.54±2.5) μmol/min. The study assumes that the collagenolytic protease purified from B. cereus MBL13 strain could be applied in the hydrolysis of waste animal bones.Izolirana je nova bakterija koja proizvodi kolagenazu, identificirana kao Bacillus cereus MBL13. Iz supernatanta kulture B. cereus MBL13, uzgojene na koštanom kolagenu kao izvoru ugljika i dušika, izdvojena je ekstracelularna proteaza sa sposobnošću razgradnje životinjskih kostiju. Procijenjena je molekularna masa pročišćene kolagenolitičke proteaze od (38,0±1,5) kDa. Analiziran je aminokiselinski sastav i utvrđeno da enzim sadržava veliku količinu asparagina, lizina i serina. Optimalna temperatura za aktivnost kolagenaze bila je 40 °C, a optimalna pH-vrijednost 8,0. Prema utjecaju iona metala, inhibitora i proteinskih supstrata na aktivnost enzima zaključeno je da enzim pripada u grupu metaloproteaza. Kolagen tipa I (tipični sastojak životinjskih kostiju) upotrijebljen je kao supstrat pri određivanju parametara Michaelis-Mentenove kinetike. Km vrijednost bila je (1,31±0,05) g/L, a vmax (12,54±2,5) μmol/min. Zaključeno je da se kolagenolitička proteaza izdvojena iz B. cereus MBL13 može upotrijebiti za razgradnju životinjskih kostiju

    Purifikacija i svojstva kolagenolitičke proteaze proizvedene s pomoću Bacillus cereus MBL13

    Get PDF
    A novel collagenase-producing bacterium has been isolated and identified as Bacillus cereus MBL13. From the culture supernatant of B. cereus MBL13 grown on bone collagen as the sole carbon and nitrogen source, an extracellular protease with novel property of hydrolyzing waste animal bones was purified. The molecular mass of the purified collagenolytic protease was estimated to be (38.0±1.5) kDa. As determined by amino acid analysis, it had high contents of asparagine, lysine and serine. The optimum temperature and pH for the collagenase activity were 40 °C and pH=8.0, respectively. The results of the effects of some metal ions, inhibitors and protein substrates suggested that the purified collagenolytic protease is a member of the metalloproteases. Type I collagen (the typical collagen in animal bone) was used as the substrate for determination of Michaelis-Menten kinetics. The obtained Km value was (1.31±0.05) g/L and the corresponding vmax value was (12.54±2.5) μmol/min. The study assumes that the collagenolytic protease purified from B. cereus MBL13 strain could be applied in the hydrolysis of waste animal bones.Izolirana je nova bakterija koja proizvodi kolagenazu, identificirana kao Bacillus cereus MBL13. Iz supernatanta kulture B. cereus MBL13, uzgojene na koštanom kolagenu kao izvoru ugljika i dušika, izdvojena je ekstracelularna proteaza sa sposobnošću razgradnje životinjskih kostiju. Procijenjena je molekularna masa pročišćene kolagenolitičke proteaze od (38,0±1,5) kDa. Analiziran je aminokiselinski sastav i utvrđeno da enzim sadržava veliku količinu asparagina, lizina i serina. Optimalna temperatura za aktivnost kolagenaze bila je 40 °C, a optimalna pH-vrijednost 8,0. Prema utjecaju iona metala, inhibitora i proteinskih supstrata na aktivnost enzima zaključeno je da enzim pripada u grupu metaloproteaza. Kolagen tipa I (tipični sastojak životinjskih kostiju) upotrijebljen je kao supstrat pri određivanju parametara Michaelis-Mentenove kinetike. Km vrijednost bila je (1,31±0,05) g/L, a vmax (12,54±2,5) μmol/min. Zaključeno je da se kolagenolitička proteaza izdvojena iz B. cereus MBL13 može upotrijebiti za razgradnju životinjskih kostiju
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