Teste de fungicidas em viveiros para controle do "mal das folhas" da seringueira.

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Neoadjuvant use of Imiquimod Before Surgery in Extramammary Paget’s Disease

A doença de Paget extramamária (DPEM) é uma neoplasia maligna cutânea, rara, observada principalmente em mulheres caucasianas pós-menopausa. A cirurgia é o tratamento mais comum. No entanto, no que diz respeito à DPEM vulvar, o seu tratamento cirúrgico passa frequentemente por cirurgia radical, que pode ser mutilante e levar à perda de feminilidade. Recentes avanços terapêuticos têm incluído abordagem médica e multimodal médico-cirúrgico, permitindo uma maior preservação da anatomia genital e subsequente diminuição da morbilidade. Neste sentido, imiquimod tem sido utilizado, off-label, como monoterapia ou terapêutica adjuvante na DPEM.Relatamos o caso de uma mulher com DPEM extenso na área anogenital submetida a resseção cirúrgica complementada com reconstrução plástica e precedida de tratamento médico com imiquimod. O imiquimod neoadjuvante permitiu uma citorredução significativa da área tumoral, minimizando a radicalidade cirúrgica, mantendo a função local e a morfologia.Extramammary Paget's disease (EMPD) is a distinct form of a rare malignant skin neoplasm, primarily seen in postmenopausal Caucasian women. Surgery is the most common treatment. However, concerning vulvar EMPD, radical surgery can be mutilating and leads to loss of femininity. Recent therapeutic development has included medical and medical-surgical approaches, allowing better preservation of genital anatomy with subsequent reduced morbidity. Accordingly, off-label use of imiquimod has been reported as a monotherapy or adjuvant therapy in EMPD.We report the case of a woman with extensive EMPD in the anogenital area, submitted to surgical resection complemented with plastic reconstruction and preceded by imiquimod medical treatment. Neoadjuvant imiquimod induced a significant cytoreduction of the tumor area, minimizing surgical radicality and maintaining local function and morpholog

Specific heat and magnetic measurements in Nd0.5Sr0.5MnO3, Nd0.5Ca0.5MnO3 and Ho0.5Ca0.5MnO3 samples

We studied the magnetization as a function of temperature and magnetic field in the compounds Nd0.5Sr0.5MnO3, Nd0.5Ca0.5MnO3 and Ho0.5Ca0.5MnO3. It allowed us to identify the ferromagnetic, antiferromagnetic and charge ordering phases in each case. The intrinsic magnetic moments of Nd3+ and Ho3+ ions experienced a short range order at low temperatures. We also did specific heat measurements with applied magnetic fields between 0 and 9 T and temperatures between 2 and 300 K in all three samples. Close to the charge ordering and ferromagnetic transition temperatures the specific heat curves showed peaks superposed to the characteristic response of the lattice oscillations. Below 10 K the specific heat measurements evidenced a Schottky-like anomaly for all samples. However, we could not successfully fit the curves to either a two level nor a distribution of two-level Schottky anomaly. Our results indicated that the peak temperature of the Schottky anomaly was higher in the compounds with narrower conduction band.Comment: submitted to PR

Unusual magnetic relaxation behavior in La0.5Ca0.5MnO3 and Nd0.5Sr0.5MnO3

We have carried out a systematic magnetic relaxation study, measured after applying and switching off a 5 T magnetic field to polycrystalline samples of La0.5Ca0.5MnO3 and Nd0.5Sr0.5MnO3. The long time logarithmic relaxation rate (LTLRR), decreased from 10 K to 150 K and increased from 150 K to 195 K in La0.5Ca0.5MnO3. This change in behavior was found to be related to the complete suppression of the antiferromagnetic phase above 150 K and in the presence of a 5 T magnetic field. At 195 K, the magnetization first decreased, and after a few minutes increased slowly as a function of time. Moreover, between 200 K and 245 K, the magnetization increased throughout the measured time span. The change in the slope of the curves, from negative to positive at about 200 K was found to be related to the suppression of antiferromagnetic fluctuations in small magnetic fields. A similar temperature dependence of the LTLRR was found for the Nd0.5Sr0.5MnO3 sample. However, the temperature where the LTLRR reached the minimum in Nd0.5Sr0.5MnO3 was lower than that of La0.5Ca0.5MnO3. This result agrees with the stronger ferromagnetic interactions that exist in Nd0.5Sr0.5MnO3 in comparison to La0.5Ca0.5MnO3. The above measurements suggested that the general temperature dependence of the LTLRR and the underlying physics were mainly independent of the particular charge ordering system considered. All relaxation curves could be fitted using a logarithmic law at long times. This slow relaxation was attributed to the coexistence of ferromagnetic and antiferromagnetic interactions between Mn ions, which produced a distribution of energy barriers.Comment: Accepted to PRB as a regular article, 10 figures, Scheduled Issue: 01 June 200

Avaliação do comportamento de clones de seringueira (Hevea spp.) no município de Ouro Preto D'Oeste, Rondônia.

Procurou-se avaliar clones de seringueira que tenham melhor comportamento e nível de exploração comercial no município de Ouro Preto D'Oeste, Rondônia. Concluiu-se que IAN 717 foi o clone que melhor se comportou nas condições experimentais; Medições de espessura de casca e de circunferência do caule podem ser realizadas bienalmente e nao anualmente.bitstream/item/55884/1/COT2816-0001.pd

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Production of the microbial pigments is one of the emerging fields of research due to a growing interest of the industry for safer products, easily degradable and eco-friendly. Fungi constitute a valuable source of pigments because they are capable of producing high yields of the substance in the cheap culture medium, making the bioprocess economically viable on the industrial scale. Some fungal species produce a dark-brown pigment, known as melanin, by oxidative polymerization of phenolic compounds, such as glutaminyl-3,4-dihydroxybenzene (GDHB) or catechol or 1,8-dihydroxynaphthalene (DHN) or 3,4-dihydroxyphenylalanine (DOPA). This pigment has been reported to act as “fungal armor” due to its ability to protect fungi from adverse conditions, neutralizing oxidants generated in response to stress. Apart from the scavenging activity, melanin exhibits other biological activities, including thermoregulatory, radio- and photoprotective, antimicrobial, antiviral, cytotoxic, anti-inflammatory, and immunomodulatory. Studies have shown that the media composition and cultivation conditions affect the pigment production in fungi and the manipulation of these parameters can result in an increase in pigment yield for large-scale pigment production. This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology

Associação da seringueira com a cultura do cafeeiro no Estado de Rondonia.

Tema Central: Sistemas Agroflorestais no Desenvolvimento Sustentavel. v.2 Trabalhos voluntarios. Editores Luciano J. Montoya e Moacir J.S. Medrado

GeoPAC: Sistema de Monitoramento de Obras do PAC.

O objetivo deste documento é descrever o sistema GeoPAC. São apresentados seu histórico de desenvolvimento, sua arquitetura de software, suas principais funcionalidades e alguns exemplos de análises de contexto territorial elaboradas pela Embrapa, a partir dos dados espaciais dos empreendimentos do PAC catalogados pelo sistema. O GeoPAC está disponível remotamente para o Ministério do Planejamento, Orçamento e Gestão (MPOG) e é fornece diversos parâmetros e indicadores utilizados no acompanhamento territorial dos empreendimentos do PAC.bitstream/item/98227/1/20140225-GeoPAC2.pd

Análise Morfométrica de Bacia Hidrográfica: Subsídio à Gestão Territorial Estudo de Caso no Alto e Médio Mamanguape.

Para esta análise, foram criados os mapas da drenagem e hipsométrico, levando em conta que o relevo é um dos aspectos mais importantes deste estudo, pois permite compreender a disposição da drenagem e tem aplicação direta para a gestão territorial. A análise da morfometria utilizou 17 índices morfométricos entre os mais de 50 existentes na literatura, dentre os quais podem-se destacar: fator de forma; índice de circularidade; coeficiente de compacidade; índice de rugosidade; padrão de drenagem; canais de drenagem; amplitude altimétrica; densidade de drenagem; textura topográfica; e coeficiente de manutenção. Com base na análise dos resultados, pode-se concluir que o fator de forma (0,44), o índice de circularidade (0,78), o coeficiente de compacidade (1,12) e o índice de rugosidade (0,72) demonstraram que a bacia hidrográfica em estudo exibe um formato alongado contribuindo, dessa forma, para o processo de escoamento e apresentando, portanto, baixa suscetibilidade à ocorrência de enchentes. Enfim, esses parâmetros podem ser utilizados para comparação entre os diversos tipos de áreas como microbacias, fazendas ou municípios, auxiliando, no monitoramento, análise e gestão territorial.bitstream/item/84896/1/0000010346-BPD-Analise-morfometrica.pd