658 research outputs found

    Scotland Registry for Ankylosing Spondylitis (SIRAS) – Protocol

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    Funding SIRAS was funded by unrestricted grants from Pfizer and AbbVie. The project was reviewed by both companies, during the award process, for Scientific merit, to ensure that the design did not compromise patient safety, and to assess the global regulatory implications and any impact on regulatory strategy.Publisher PD

    Efficacy of HIV/STI behavioral interventions for heterosexual African American men in the United States: a meta-analysis

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    This meta-analysis estimates the overall efficacy of HIV prevention interventions to reduce HIV sexual risk behaviors and sexually transmitted infections (STIs) among heterosexual African American men. A comprehensive search of the literature published during 1988–2008 yielded 44 relevant studies. Interventions significantly reduced HIV sexual risk behaviors and STIs. The stratified analysis for HIV sexual risk behaviors indicated that interventions were efficacious for studies specifically targeting African American men and men with incarceration history. In addition, interventions that had provision/referral of medical services, male facilitators, shorter follow-up periods, or emphasized the importance of protecting family and significant others were associated with reductions in HIV sexual risk behaviors. Meta-regression analyses indicated that the most robust intervention component is the provision/referral of medical services. Findings indicate that HIV interventions for heterosexual African American men might be more efficacious if they incorporated a range of health care services rather than HIV/STI-related services alone

    Longitudinal Education and Career Outcomes of a Cancer Research Training Program for Underrepresented Students: The Meharry-Vanderbilt-Tennessee State University Cancer Partnership

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    This study examined longitudinal education and career outcomes of the Meharry-Vanderbilt-Tennessee State University Cancer Partnership, the longest-running National Cancer Institute (NCI) Comprehensive Partnerships in Advancing Cancer Health Equity (CPACHE) program site in the United States. Degree completion rates were calculated and progression along the entire postsecondary “pipeline” was quantified for 204 participants recruited between 2011 and 2020. For participants who had entered the workforce, career outcomes were also analyzed. Relative to comparison data, participants completed degrees and progressed through the higher education “pipeline” to earn advanced degrees at remarkably high rates; the majority entered careers in which they support or conduct cancer research. The latter is important, because most participants identify with demographic categories currently underrepresented in the cancer research workforce. This article makes two contributions to knowledge on research training programs for underrepresented students: 1) it quantifies participants’ progression along the entire postsecondary education pipeline as well as into the workforce, and 2) it identifies points where participants are most prone to exit the pipeline rather than progress. We identify two types of exits—permanent and temporary—and offer empirically supported operational definitions for both. Evaluators may find the quantitative model and/or definitions useful for analyzing similar programs

    A Look into Increasing the Number of Veterans and Former Government Employees Converting to Career and Technical Cybersecurity Teachers

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    The current state of technology with recent explosions in the digital processing of paperwork, computer networking use, and online and virtual approaches to areas, which until very recently had traditional and non-computerized ways of operating, led to a steady increase in the demand for jobs in the area of computer science and cybersecurity. The education system, the pipeline for the incoming workforce, needs to keep up with this tremendous pace in technology and the job market. The current K-12 school system has been extensively challenged to fill out necessary positions in order to address the increasing need for programs that respond to industry and government entity gaps in employment. The COVID-19 pandemic forced a large segment of the economy to swiftly move to virtual working and virtual learning. This further increased the already large demand for cybersecurity jobs and accelerated the pace at which the development of necessary education pathways is required. The education system, on all different levels, needs to adjust to this pace in order to enable a large number of future graduates to fill these new jobs. There is currently a large gap in the number of K-12 level teachers available in the area of career and technical education. One possible solution to this problem may come from a specific segment of the workforce, veterans. This paper will provide an overview of different challenges that many veterans are facing after joining career switcher programs for future teachers

    An Initial Look into the Computer Science and Cybersecurity Pathways Project for Career and Technical Education Curricula

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    Computer science and cybersecurity have gained the attention of various stakeholders, industry representatives, educators, parents and students who are thinking about their future careers. Teaching computer science courses has moved into K-12 education, no longer introduced in the college classroom. There are various reasons for this trend. One is that in this way more children have access to the curriculum that integrates computer science principles, not just those undergraduate students in specific STEM majors. Other industries need different levels of computer science and cybersecurity education. There are various programs across the nation that are focusing on introducing these topics as early as elementary school through various outreach programs or even in the regular curriculum. In 2014, Governor Terry McAuliffe (Commonwealth of Virginia) established the “Cyber Virginia and the Virginia Cyber Security Commission” with recommendations that a cybersecurity workforce pipeline should start in K-12 education and that various pathways should be developed and implemented across the Commonwealth. This paper will provide an initial look into a project funded by the Department of Education that is focused on the Career and Technical Education (CTE) pathways in Computer Science and Cybersecurity. It is the first year of implementation

    The Role of Stress in Understanding Differences in Sedentary Behavior in Hispanic/Latino Adults: Results from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study

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    Chronic stress and/or lifetime traumatic stress can create a self-reinforcing cycle of unhealthy behaviors, such as overeating and sedentary behavior, that can lead to further increases in stress. This study examined the relationship between stress and sedentary behavior in a sample of Hispanic/Latino adults (N = 4244) from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study

    Mentoring Prospective Engineering Students Through the After School Program Girls in Engineering Focused on Building an Underwater Remotely Operated Vehicle

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    A number of studies by engineering education researchers have pointed out that all-female teams, rather than mixed teams, result in better forms of participation and interaction in engineering related after-school programs and clubs. In particular, for after-school programs or clubs that form in response to a STEM competition, all-female teams have better chances of developing. One such competition, which will be discussed in this paper, is a regional Marine Advanced Technology Education (MATE) competition in which students from Blind_Review High School have been participating for many years.For each year’s competition, an all-female team of students enrolled in the Career and Technical Education program at Blind_Review High School, City, State build an underwater autonomous robotic vehicle, for which the robot specifications and competition rules are formulated each year by the MATE regional competition. Any team participating in the competition must have a mentor, and the students must be enrolled in courses within the engineering studies program. This paper will discuss the collaboration developed between the high school and college students, how the mentorship program was delivered, and how the program successfully helped future engineering students to establish their engineering and future STEM identities

    Assessing Asthma Symptoms in Adolescents and Adults : Qualitative Research Supporting Development of the Asthma Daily Symptom Diary

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    We thank the members of the US Food and Drug Administration’s Qualification Review Team for their feedback during the development of the ADSD. Source of financial support: Funding for this research was provided by the following PRO Consortium member firms: Actelion; Amgen; AstraZeneca; Boehringer-Ingelheim; Forest Laboratories; Genentech; GlaxoSmithKline; Ironwood Pharmaceuticals; Janssen, Merck, Sharp & Dohme Corp.; Novartis; Pfizer; and Sanofi. In addition, Critical-Path Institute’s PRO Consortium is supported by Critical-Path Public-Private Partnerships (grant no. 1U18FD005320) from the US Food and Drug Administration.Peer reviewedPublisher PD

    Radiometric Stability of the SABER Instrument

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    The SABER instrument on the National Aeronautics and Space Administration Thermosphere‐Ionosphere‐Mesosphere Energetics and Dynamics satellite continues to provide a long‐term record of Earth\u27s stratosphere, mesosphere, and lower thermosphere. The SABER data are being used to examine long‐term changes and trends in temperature, water vapor, and carbon dioxide. A tacit, central assumption of these analyses is that the SABER instrument radiometric calibration is not changing with time; that is, the instrument is stable. SABER stratospheric temperatures and those derived from Global Positioning System Radio Occultation measurements are compared to examine SABER\u27s stability. Global Positioning System Radio Occultation measurements are inherently stable due to the accuracy and traceability of the measured phase delay rate to the Système Internationale definition of the second. Differences in global annual mean SABER and COSMIC lower stratospheric temperatures show little significant change with time in the 11 years spanning 2007–2017. From this analysis we infer that SABER temperatures are stable to better than 0.1 to 0.2 K per decade
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