671 research outputs found

    Colovesical fistulae in the sigmoid diverticulitis

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    Nella maggior parte dei casi le fistole colovescicali rappresentano una complicanza della malattia diverticolare e sono la tipologia più comune di fistola colodigestiva; meno comuni sono le fistole colovaginali, colocutanee, coloenteriche e colouterine. Nel presente lavoro abbiamo effettuato una review della letteratura riguardante le fistole colovescicali in chirurgia colorettale per diverticolite del sigma. Decriviamo anche due casi che hanno richiesto un trattamento chirurgico, in uno in elezione e nell’altro in urgenza. In entrambi i casi abbiamo eseguito una resezione colica con anastomosi primaria e minimaresezione vesvicale con posizionamento di catetere di Foley in media per 10 giorni

    Enabling Process Variants and Versions in Distributed Object-Aware Process Management Systems

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    Business process variants are common in many enterprises and properly managing them is indispensable. Some process management suites already offer features to tackle the challenges of creating and updating multiple variants of a process. As opposed to the widespread activity-centric process modeling paradigm, however, there is little to no support for process variants in other process support paradigms, such as the recently proposed artifact-centric or object-aware process support paradigm. This paper presents concepts for supporting process variants in the object-aware process management paradigm. We offer insights into the distributed object-aware process management framework PHILharmonicFlows as well as the concepts it provides for implementing variants and versioning support based on log propagation and log replay. Finally, we examine the challenges that arise from the support of process variants and show how we solved these, thereby enabling future research into related fundamental aspects to further raise the maturity level of data-centric process support paradigms

    Iron-binding properties of sugar cane yeast peptides

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    AbstractThe extract of sugar-cane yeast (Saccharomyces cerevisiae) was enzymatically hydrolysed by Alcalase, Protex or Viscozyme. Hydrolysates were fractionated using a membrane ultrafiltration system and peptides smaller than 5kDa were evaluated for iron chelating ability through measurements of iron solubility, binding capacity and dialyzability. Iron-chelating peptides were isolated using immobilized metal affinity chromatography (IMAC). They showed higher content of His, Lys, and Arg than the original hydrolysates. In spite of poor iron solubility, hydrolysates of Viscozyme provided higher iron dialyzability than those of other enzymes. This means that more chelates of iron or complexes were formed and these kept the iron stable during simulated gastro-intestinal digestion in vitro, improving its dialyzability

    A severe case of hemobilia and biliary fistula following an open urgent cholecystectomy

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    <p>Abstract</p> <p>Background</p> <p>Cholecystectomy has been the treatment of choice for symptomatic gallstones, but remains the greatest source of post-operative biliary injuries. Laparoscopic approach has been recently preferred because of short hospitalisation and low morbidity but has an higher incidence of biliary leakages and bile duct injuries than open one due to a technical error or misinterpretation of the anatomy. Even open cholecystectomy presents a small number of complications especially if it was performed in urgency. Hemobilia is one of the most common cause of upper gastrointestinal bleeding from the biliary ducts into the gastrointestinal tract due to trauma, advent of invasive procedures such as percutaneous liver biopsy, transhepatic cholangiography, and biliary drainage.</p> <p>Methods</p> <p>We report here a case of massive hemobilia in a 60-year-old man who underwent an urgent open cholecystectomy and a subsequent placement of a transhepatic biliary drainage.</p> <p>Conclusion</p> <p>The management of these complications enclose endoscopic, percutaneous and surgical therapies. After a diagnosis of biliary fistula, it's most important to assess the adequacy of bile drainage to determine a controlled fistula and to avoid bile collection and peritonitis. Transarterial embolization is the first line of intervention to stop hemobilia while surgical intervention should be considered if embolization fails or is contraindicated.</p

    Environmental and Agro-Economic Sustainability of Olive Orchards Irrigated with Reclaimed Water under Deficit Irrigation

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    This study explores the effects of the adoption of reclaimed water (RW) as source of irrigation in conjunction with the application of deficit irrigation strategies in an olive orchard (different genotypes) located within the “Valle dei Margi” farmhouse (Eastern Sicily). Specifically, the RW was obtained in situ by treating the wastewater coming from the farmhouse throughout a treatment wetland system (TW). The effects of RW on crop water status (CWS) was assessed by conducting plant-based measurements (i.e., leaf water potential, Ψ, and leaves relative water content, RWC) and determining satellite-based biophysical indicators. An economical and environmental evaluation of the proposed sustainable irrigation practices was carried out by using the life cycle assessment (LCA) approach.The RW quality showed high variability due to fluctuations in the number of customers at the farmhouse during the Covid-19 pandemic period. However, high removal efficiency of the overall TW was reached even if the RW quality did not always accomplish with the limits of the Italian regulations. A strong impact in the variation of Ψ was observed among the olive orchard under the different water regimes, evidencing how CWS performances are greatly conditioned by the genotype. However, no differences in leaves RWC and in satellite-based biophysical indicators were detected, despite the severe water deficit imposed (i.e., 50% of irrigation water reduction). Finally, the results of the LCA analysis underlined that the use of RW may permit to obtain important gains both in economic and environmental terms, thus representing a valid strategy for the olive cultivation

    Antonio Gramsci’s impact on critical pedagogy

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    This paper provides an account of Antonio Gramsci’s impact on the area of critical pedagogy. It indicates the Gramscian influence on the thinking of major exponents of the field. It foregrounds Gramsci's ideas and then indicates how they have been taken up by a selection of critical pedagogy exponents who were chosen on the strength of their identification and engagement with Gramsci's ideas, some of them even having written entire essays on Gramsci. The essay concludes with a discussion concerning an aspect of Gramsci's concerns, the question of powerful knowledge, which, in the present author's view, provides a formidable challenge to critical pedagogues.peer-reviewe

    The VENERE study: EffectiVenEss of a rehabilitation treatment with Nordic walking in obEse or oveRweight diabetic patiEnts with cardiovascular disease

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    Background. Nordic walking (NW) has several potential benefits for individuals with cardiovascular disease (CV), type 2 diabetes, and obesity/overweight. It improves cardiovascular health, including exercise capacity and blood pressure control. It enhances glycemic control and insulin sensitivity in diabetes. It aids in weight management and body composition improvement. NW offers additional advantages such as improved muscular strength, joint mobility, physical activity levels, and psychological well-being. Methods. This open-label study with three arms will aim to evaluate the efficacy, safety, and adherence to exercise prescription in obese/overweight diabetic patients with CV complications. The primary objective will be to assess the CV performance of participants after a 6- and 12-month follow-up period, following a 3-month NW intervention, compared with standard rehabilitation (SR) and cardiological counseling (control group, CG) training lasting 3 months. Results. The results of the study will provide valuable insights into the comparative effectiveness of a NW intervention versus SR and CG training in improving cardiovascular performance in obese/overweight diabetic patients with CV complications. Additionally, safety and adherence data will help inform the feasibility and sustainability of the exercise prescription over an extended period. Conclusions. These findings may have implications for the development of tailored exercise programs for this specific patient population, with the aim of optimizing cardiovascular health outcomes. This protocol was registered on ClinicalTrials.gov with reference ID: NCT05987410 on 10 August 2023
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