4,725 research outputs found

    Going Straight: The Politics of Time and Space in David Eldridge’s Incomplete and Random Acts of Kindness

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    Amelia Howe Kritzer states that a contemporary British play is commonly thought of as political if it presents "a political issue or comments on what is already perceived as a political issue" (10). Since 1989, however, the economic and political system in the UK has become increasingly monologic. In such a monologic political system, Shavian dialogic forms of political theatre, which present a dialectical discussion of a political issue, lose their efficacy. As a result, some British playwrights have moved toward more interventionist strategies of political engagement, which involve our lived experience of social structures through their dramaturgy. These plays re-order normative representations of social structures, of offering a symbolic re-ordering of social structures within their form. As such, their form represents what Adorno terms, "and analogy of that other condition which should be" (194). David Harvey argues that in late capitalist society, our experience of time and space has become increasingly compressed. Consequently, our temporary axis of succession, which constitutes the fundamental organisation of Shavian drama, no longer reflects our lived experience of time in the world outside the theatre. Therefore, plays that re-order structures of time and space have political efficacy in that they expose a gap between representations of time and space as linear and concrete and our lived experience of time and space as compressed. This essay argues that David Eldridge's 'Incomplete and Random Acts of Kindness' articulates a complete breakdown in the temporal axis of succession in its structure. Its dramaturgy reflects the experience of space-time compression. Thus, it is a highly political play, not on the basis of its content, but in terms of the way in which its structure mediates and negotiates our lived experience of social structures under the pressures of late capitalism

    Control of the morphology on selective area growth of GaN nanocolumns by rf-plasma-assisted

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    Selective area growth (SAG) of GaN nanocolumns (NCs), making use of patterned or masked (nanoholes) substrates, yields a periodic, homogeneous distribution of nanostructures, that makes their processing much easier compared with self-assembled ones. In addition, the control on the diameter and density of NCs avoids dispersion in the electrooptical characteristics of the heterostructures based on this type of material (embedded InGaN/GaN quantum disks for example). Selective area growth using a mask with nanohole arrays has been demonstrated by rf-plasma-assisted MBE [1, 2]

    Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group

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    Introduction: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known. Method: This study was carried out prospectively in the multinational EULAR Scleroderma Trial and Research database by amending the electronic data-entry system with the International Index of Erectile Function-5 and items related to ED risk factors and treatment. Centres participating in this EULAR Scleroderma Trial and Research substudy were asked to recruit patients consecutively. Results: Of the 130 men studied, only 23 (17.7%) had a normal International Index of Erectile Function-5 score. Thirty-eight per cent of all participants had severe ED (International Index of Erectile Function-5 score ≤ 7). Men with ED were significantly older than subjects without ED (54.8 years vs. 43.3 years, P < 0.001) and more frequently had simultaneous non-SSc-related risk factors such as alcohol consumption. In 82% of SSc patients, the onset of ED was after the manifestation of the first non-Raynaud's symptom (median delay 4.1 years). ED was associated with severe cutaneous, muscular or renal involvement of SSc, elevated pulmonary pressures and restrictive lung disease. ED was treated in only 27.8% of men. The most common treatment was sildenafil, whose efficacy is not established in ED of SSc patients. Conclusions: Severe ED is a common and early problem in men with SSc. Physicians should address modifiable risk factors actively. More research into the pathophysiology, longitudinal development, treatment and psychosocial impact of ED is needed

    Insights from Amphioxus into the Evolution of Vertebrate Cartilage

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    Central to the story of vertebrate evolution is the origin of the vertebrate head, a problem difficult to approach using paleontology and comparative morphology due to a lack of unambiguous intermediate forms. Embryologically, much of the vertebrate head is derived from two ectodermal tissues, the neural crest and cranial placodes. Recent work in protochordates suggests the first chordates possessed migratory neural tube cells with some features of neural crest cells. However, it is unclear how and when these cells acquired the ability to form cellular cartilage, a cell type unique to vertebrates. It has been variously proposed that the neural crest acquired chondrogenic ability by recruiting proto-chondrogenic gene programs deployed in the neural tube, pharynx, and notochord. To test these hypotheses we examined the expression of 11 amphioxus orthologs of genes involved in neural crest chondrogenesis. Consistent with cellular cartilage as a vertebrate novelty, we find that no single amphioxus tissue co-expresses all or most of these genes. However, most are variously co-expressed in mesodermal derivatives. Our results suggest that neural crest-derived cartilage evolved by serial cooption of genes which functioned primitively in mesoderm
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