104 research outputs found
Direitos humanos e refĂșgio: uma anĂĄlise sobre o momento anterior Ă determinação do status de refugiado
Highly-parallelized simulation of a pixelated LArTPC on a GPU
The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype
Supplementary Material for: First Diagnosis of Atrial Fibrillation at the Time of Stroke
<p><b><i>Background:</i></b> Atrial fibrillation (AF) is a major cause
of ischemic stroke. Individuals with undiagnosed AF lack the stroke
protection afforded by oral anticoagulants. We obtained a contemporary
estimate of the percentage of AF patients newly diagnosed at the time of
stroke. <b><i>Methods:</i></b> We identified patients admitted to the
Massachusetts General Hospital (MGH) from January 1, 2010 to December
31, 2013 with acute ischemic stroke and either previously or newly
diagnosed AF using hospital stroke registry data and stroke and AF ICD-9
code searches of hospital databases. Reviewers categorized AF as
previously known or newly diagnosed, and collected comorbidity and
outcome data. To confirm AF as newly diagnosed, we searched patients'
pre-event electronic medical records (EMRs) for AF terms. <b><i>Results:</i></b>
AF was considered newly diagnosed in 156/856 patients (18%; 95% CI
16-21). In 136/156 cases, AF was diagnosed using 12-lead EKG, telemetry,
or rhythm strips. New AF strokes had a median NIH stroke scale of 12;
60% had mRankin â„3 at discharge, including 15% deaths. Pre-stroke CHA<sub>2</sub>DS<sub>2</sub>-VASc
score was â„2 in 89%. About half (76/156) had prior records in the MGH
EMR. Evidence of pre-stroke AF, often peri-procedural, was found in
8/76, but the AF diagnosis was not carried forward. <b><i>Conclusions:</i></b>
In this contemporary cohort, nearly one in 5 AF-related strokes
occurred without a pre-stroke AF diagnosis. AF was readily diagnosed
using standard rhythm monitoring. The vast majority of patients with
newly diagnosed AF were at high enough pre-stroke risk to merit
anticoagulation. In conclusion, our findings support screening for AF
before stroke. Patients with past transient AF may merit more intensive
screening.</p
Nonspecific Esterases in the Brain and Amniotic Fluid of Rat Fetuses Following Maternal Exposure to Cyclophosphamide
Cell-mediated Cytotoxicity during Vaccinia Virus Revaccination in Man: Influence of Antibodies and Interferon
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