Symmetries of topological field theories in the BV-framework

Topological field theories of Schwarz-type generally admit symmetries whose algebra does not close off-shell, e.g. the basic symmetries of BF models or vector supersymmetry of the gauge-fixed action for Chern-Simons theory (this symmetry being at the origin of the perturbative finiteness of the theory). We present a detailed discussion of all these symmetries within the algebraic approach to the Batalin-Vilkovisky formalism. Moreover, we discuss the general algebraic construction of topological models of both Schwarz- and Witten-type.Comment: 30 page

Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration

Unlike solid organs, human airway epithelia derive their oxygen from inspired air rather than the vasculature. Many pulmonary diseases are associated with intraluminal airway obstruction caused by aspirated foreign bodies, virus infection, tumors, or mucus plugs intrinsic to airway disease, including cystic fibrosis (CF). Consistent with requirements for luminal O2, airway epithelia surrounding mucus plugs in chronic obstructive pulmonary disease (COPD) lungs are hypoxic. Despite these observations, the effects of chronic hypoxia (CH) on airway epithelial host defense functions relevant to pulmonary disease have not been investigated. Molecular characterization of resected human lungs from individuals with a spectrum of muco-obstructive lung diseases (MOLDs) or COVID-19 identified molecular features of chronic hypoxia, including increased EGLN3 expression, in epithelia lining mucus-obstructed airways. In vitro experiments using cultured chronically hypoxic airway epithelia revealed conversion to a glycolytic metabolic state with maintenance of cellular architecture. Chronically hypoxic airway epithelia unexpectedly exhibited increased MUC5B mucin production and increased transepithelial Na+ and fluid absorption mediated by HIF1α/HIF2α-dependent up-regulation of β and γENaC (epithelial Na+ channel) subunit expression. The combination of increased Na+ absorption and MUC5B production generated hyperconcentrated mucus predicted to perpetuate obstruction. Single-cell and bulk RNA sequencing analyses of chronically hypoxic cultured airway epithelia revealed transcriptional changes involved in airway wall remodeling, destruction, and angiogenesis. These results were confirmed by RNA–in situ hybridization studies of lungs from individuals with MOLD. Our data suggest that chronic airway epithelial hypoxia may be central to the pathogenesis of persistent mucus accumulation in MOLDs and associated airway wall damage

Vegetative development, fruits yield and optimization of pineapple cv. Pérola with different levels of irrigation

Apesar de ser uma planta com necessidades hídricas relativamente baixas, o abacaxizeiro tem demanda permanente de água, variável ao longo do ciclo e dependente do seu estádio de desenvolvimento. Assim, objetivou-se analisar volumes de irrigação no desenvolvimento vegetativo, no rendimento da fruta e na otimização do abacaxizeiro cv. Pérola. O experimento foi realizado na Universidade Federal de Sergipe, município de São Cristóvão (11°01'S, 37°12'W), no delineamento em blocos ao acaso, com quatro tratamentos (lâminas de água) (100% da evaporação do tanque Classe A (523,7mm ano-1); 75% da evaporação do tanque Classe A (392,8mm ano-1), 50% da evaporação do tanque Classe A (261,8mm ano-1) e 0% da evaporação do tanque Classe A, seis repetições e 12 plantas úteis por parcela. O sistema de irrigação foi por aspersão convencional disposto em linha, com pressão de 20mca e vazão de 1,33m3 h-1. A área foliar (cm2) mínima atingida de 4552,6cm2 foi observada no volume de água de 122,9mm ano-1, enquanto a massa seca das folhas (147,6g) foi constatada com 17mm ano-1. O máximo comprimento da folha D (88,9cm) foi estimado com 532,7 mm ano-1. Já o máximo comprimento do fruto (23cm) foi observado na lâmina de 296,9mm ano-1. A massa do fruto máxima estimado de 1.736g foi constatado na lâmina de 356,4mm ano-1. No contexto, a irrigação contribui de forma positiva no desenvolvimento vegetativo e rendimento da fruta do abacaxizeiro. Ressalta-se remuneração mensal líquida de R 1.161,17ha-1, quando se adota lâmina de irrigação de 356,4mm ano-1. _________________________________________________________________________________________ ABSTRACT: Regardless a relatively low water needs, pineapple fruit has a variable behavior related to water need throughout its biological cycle depending on the development stage. The objective of this work was to analyze irrigation on the vegetative development and fruits yield in pineapple cv. Pérola. The experiment was conducted at the Universidade Federal de Sergipe Experimental Station, at São Cristóvão - SE (11°01'S, 37°12'W), in a randomized block design, with four water level treatments as follow: 100% of Class-A (523.7mm ano-1) evaporation pan; 75% of Class-A (392.8mm ano-1) evaporation pan, 50% of Class-A (261.8mm ano-1) evaporation pan and 0% of Class-A evaporation pan, in six replications and twelve plants per plot. The splinkler watering system of irrigation was installed in a line, with an operating pression of 20 mca and a sprinkler dischrage of 1.33m3h-1. A minimum leaf area of 4552.6cm2 was observed, considering a water level of 122.9mm year-1, while a leaf dry matter was 147.6 g in 17mmyear-1. The maximum leaf length (D) of 88.9cm was estimated considering 532.7mmyear-1. The maximum fruit length of 23cm was observed, considering a water level of 296.9mmyear-1. The maximum estimated fruit weight was 1.736g in a water level of 356.4mm year-1. The irrigation seems to contribute in a positive way to the vegetative development in the pineapple fruit yield. It is important to mention that it could be observed a net profit of R 1,161.17 ha-1, when a water level of 356.4mm ano-1 of irrigation was adopted

Influence of the substrate in germination of lychee seeds Influência do substrato na germinação de sementes de lichia

The lychee is, all over the world, considered as the "queen of the fruits" due to the delicacy of its appearance and flavor. Although it was only recently that it started to have economical importance in Brazil, the lychee is already calling the attention of numerous farmers, mainly those who cultivate citric fruits and/or sugarcane in the State of São Paulo, due to the constant and at the same time growing necessity of finding new alternative crops. Considering that the commercial cultivation of lychee plants in the field requires the previous obtainment of rootstocks viewing to reduce the genetic variability and the length of the juvenile period displayed by plants resulting directly from the seeds, finding ways to improve the germination performance of lychee seeds for the production of rootstock plants is of considerable economic importance. Thus, the objective of this experiment was to test five substrates for the germination of lychee seeds: (1) vermiculite, (2) washed sand, (3) filter paper, (4) carbonized rice hull, and (5) sphagnum. The results showed that the period of time required by a lychee seed to germinate is a short one thus reinforcing the importance of providing a suitable substrate for the germination to take place. It was found that the substrates which apparently allowed the best combinations of water and oxygen availability for the seeds - washed sand and carbonized rice hull - were those leading to the fastest and highest germination values.<br>A lichia é considerada em todo o mundo como a rainha das frutas, por sua aparência e sabor delicado. Atualmente, a cultura vem despertando interesse, principalmente no Estado de São Paulo, onde, em virtude dos problemas enfrentados pelos agricultores, destacando-se os de laranja e cana-de-açúcar, a procura por alternativas agrícolas vem se intensificando ainda mais. A propagação através de sementes não é recomendada comercialmente, pois as plantas de pé-franco são geneticamente muito desuniformes e apresentam período juvenil muito longo, demorando até 10 anos para entrar em produção; no entanto, a semente pode ser utilizada para a obtenção de porta-enxertos. Observou-se que a germinação de sementes de lichia ocorre rapidamente, reforçando a importância do uso de um substrato adequado. Pela análise dos resultados obtidos, verifica-se que o substrato que aparentemente permitiu as melhores combinações de água e disponibilidade de oxigênio para as sementes - casca de arroz carbonizada e areia lavada, foi o que proporcionou valores de germinação mais rápidos e mais altos

Epidemiologia da leishmaniose tegumentar americana e suas relações com a lavoura e o garimpo, em localidade do Estado da Bahia (Brasil) Epidemiology of leishmaniasis related to agriculture and prospecting in a locality of the State of Bahia, Brazil

Realizou-se um estudo sobre a associação entre infecção leishmaniótica e a ocupação dos indivíduos em Lençóis-Bahia (Brasil). Foram utilizados um questionário com variáveis biológicas, sociais e econômicas e o teste de Montenegro. Houve captura de flebotomíneos em locais peri e intra-domiciliares. Encontrou-se maior prevalência da infecção no grupo ocupacional de lavradores/garimpeiros em comparação às demais ocupações. Explica-se esse resultado em razão da dupla exposição dos lavradores/garimpeiros à leishmaniose tegumentar americana, em sua área de moradia e local de trabalho.<br>This study was carried out in the city of Lençóis, State of Bahia, with the objective of verifying the association between leishmaniasis infection and occupation. A Montenegro test and a questionnaire including biological and socio-economic variables were applied to the study group. Sandflies were captured in and around dwellings. The higher-than-average prevalence of leishmaniasis observed among agricultural workers and prospectors is explained by the double exposure to the infection-both at home and at work

Crescimento e rendimento do abacaxizeiro nas condições climáticas dos Tabuleiros Costeiros do Estado da Paraíba Growth and yield of pineapple under climatic conditions of the Coastal Table Lands of Paraíba State

Um experimento de campo foi conduzido com a cultura do abacaxi, cv. Pérola, em Santa Rita, PB, durante o período março de 2001 a junho de 2002; na ocasião, avaliaram-se o desenvolvimento e o rendimento dessa cultivar, em condições de irrigação suplementar, visando obter informações que possam adequar o manejo da cultura à região. De forma geral, as variáveis de crescimento e rendimento foram compatíveis com o descrito na literatura, destacando-se que o índice de área foliar (IAF) alcançou o valor 12, aos 308 dias após plantio e os frutos com peso acima de 1,7 kg, representaram 60% do total colhido (57.000 kg). Os frutos de segunda compreenderam 30% dos frutos colhidos com peso variando de 1,3 a 1,7 kg e os frutos com peso inferior a 1,3 kg, correspondente aos 10% restantes, foram considerados de qualidade inferior e destinados principalmente à indústria de sucos e rações. O abacaxizeiro, cv Pérola, cultivado com suplementação de irrigação, nas condições de clima e solo dos tabuleiros de Santa Rita, PB, apresentou IAF, tamanho de frutos e rendimento superiores aos obtidos em outras regiões do Brasil, seja em sequeiro ou em condições irrigadas.<br>A field experiment was carried out with the pineapple, cultivar Pérola, in Santa Rita in the State of Paraíba, Brazil, during the period from March, 2001 to June, 2002. The development and yield of crop under supplemental irrigation conditions was evaluated in order to obtain information for improving crop management in the region. The growth and yield variables were compatible with those obtained in other studies. The results showed that the leaf area index (LAI) reached a value of 12, 308 days after planting and the fruits with weight above 1.7 kg reached 60% of the total harvested fruits. The fruit of 2nd category, with weight between 1.3 and 1.7 kg, represented 30% of the total fruit production while the remaining 10% of fruits harvested with weight less than 1.3 kg, were considered of lower quality and sent to the juice and animal food industry. The pineapple crop, cv Pérola, grown under climate and Costal Table Land soil of Santa Rita, PB, presented LAI, size of fruit and yield greater than those obtained in other regions of Brazil, even in irrigated areas