20 research outputs found
EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI) : Study protocol for a multicentre, observational trial
More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369
Les glucides et les lipides du clitellum et de l'albumen du cocon chez Eisenia fetida Sav (annélide oligochète)
International audienc
Analyse des réserves nutritives protéiques du clitellum et de l'albumen du cocon chez Eisenia fetida Sav (annélide oligochète). Mise en évidence d'une glycolipoprotéine comparable à une vitellogénine
International audienc
Structural and electrical properties of as-deposited and annealed DC sputtered ITO thin films
We have studied the effect of annealing on the structural and electrical properties of
tin-doped indium oxyde, (ITO), thin films prepared by DC sputtering at different
partial pressure of oxygen (ppo). Annealing experiments have been done in vacuum and in Ar
atmosphere up to a temperature of 450 °C.
A change of texture from to as the
ppo was increased was noted in the as-deposited films. Annealing induced cristallinity and
improved the texture of these films. The lattice constant decreased after annealing. The (222)
grain size increased after vacuum annealing but was unaffected by annealing in Ar atmosphere;
while the (400) grain size decreased for samples having the texture. The electrical
resistivity decreases sharply after annealing to a minimum value of
87 × 10-4 Ω cm
Removal of Ni(II) ions from wastewater by micellar enhanced ultrafiltration using mixed surfactants
P4-31: Clinical and etiological profile malignant hypertension in children in pediatric intensive care
Influence of ion implantation parameters on the perpendicular magnetic anisotropy of Fe-N thin films with stripe domains
International audienc