171 research outputs found

    Трансфер технологий в образовательной сфере и осуществление инновационного процесса

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    The article discusses topical issues related to the need to stimulate the innovative development of the economy, analyzes the concept of the innovation process. Special attention is paid to the importance of technology transfer in ensuring the innovation cycle

    Symmetries and modelling functions for diffusion processes

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    A constructive approach to theory of diffusion processes is proposed, which is based on application of both the symmetry analysis and method of modelling functions. An algorithm for construction of the modelling functions is suggested. This algorithm is based on the error functions expansion (ERFEX) of experimental concentration profiles. The high-accuracy analytical description of the profiles provided by ERFEX approximation allows a convenient extraction of the concentration dependence of diffusivity from experimental data and prediction of the diffusion process. Our analysis is exemplified by its employment to experimental results obtained for surface diffusion of lithium on the molybdenum (112) surface pre-covered with dysprosium. The ERFEX approximation can be directly extended to many other diffusion systems.Comment: 19 pages, 8 figure

    Подготовка специалистов в области электронного маркетинга: кадры для цифровой экономики Республики Беларусь

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    The tendencies of development of marketing in conditions of digital transformation of economy are considered in the article. The concept of electronic marketing is presented. The condition of training of specialists in the field of electronic marketing in the Republic of Belarus is described. The necessity of training of specialists in the field of e-marketing on the second stage of higher education is substantiated. The special features of this field of study are distinguished in comparison with the baccalaureate and in comparison with related directions of the master's programm. В статье рассматриваются тенденции развития маркетинга в условиях цифровой транс- формации экономики. Представлено понятие электронного маркетинга, дана характеристика состояния подготовки специалистов в области электронного маркетинга в Республике Беларусь. Обоснована необхо- димость открытия специальности «Электронный маркетинг» на II ступени высшего образования, выделены особен- ности данной специальности по сравнению с I ступенью и по сравнению со смежными направлениями подготовки магистров.

    Management of professional self-determination of applicants at the technical university

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    Рассматриваются проблемы формирования контингента конкурентоспособных обучающихся в университете. Показана необходимость и современные способы управления профессиональным самоопределением абитуриентов. Предложено активнее использовать современные образовательные электронные технологии при организации профориентационной работы. Problems of competitive students contingent forming at the university are considered. The necessity and modern methods of professional self-determination managing of entrants are shown. It is proposed to make active use of modern educational electronic technologies when organizing vocational guidance work

    Glutathione Precursor N-Acetyl-Cysteine Modulates EEG Synchronization in Schizophrenia Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

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    Glutathione (GSH) dysregulation at the gene, protein, and functional levels has been observed in schizophrenia patients. Together with disease-like anomalies in GSH deficit experimental models, it suggests that such redox dysregulation can play a critical role in altering neural connectivity and synchronization, and thus possibly causing schizophrenia symptoms. To determine whether increased GSH levels would modulate EEG synchronization, N-acetyl-cysteine (NAC), a glutathione precursor, was administered to patients in a randomized, double-blind, crossover protocol for 60 days, followed by placebo for another 60 days (or vice versa). We analyzed whole-head topography of the multivariate phase synchronization (MPS) for 128-channel resting-state EEGs that were recorded at the onset, at the point of crossover, and at the end of the protocol. In this proof of concept study, the treatment with NAC significantly increased MPS compared to placebo over the left parieto-temporal, the right temporal, and the bilateral prefrontal regions. These changes were robust both at the group and at the individual level. Although MPS increase was observed in the absence of clinical improvement at a group level, it correlated with individual change estimated by Liddle's disorganization scale. Therefore, significant changes in EEG synchronization induced by NAC administration may precede clinically detectable improvement, highlighting its possible utility as a biomarker of treatment efficacy

    Внедрение цифрового управления проектами строительства и эксплуатации энергоэффективных жилых домов

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    The paper considers an issue of transition to digital management technologies in the field of construction and housing and communal services in Russia, as well as in other countries. An optimization methodology for the application of  the digital  economy  has been developed using  the example of  the existing  real  estate  management  system in the  Stolichny Microdistrict of Izhevsk city (Udmurt Republic, Russian Federation). The existing and developed new projects of digital technologies are described, the introduction of which will increase the efficiency of the construction and operation of residential buildings. A methodology has been formed for creating an optimization mathematical model for managing construction and operation projects of energy-efficient residential buildings. Prerequisites and a scheme for the joint implementation of this model and digital technologies are given to improve the quality of construction and operation of residential buildings. The paper proposes a phased methodology for the introduction of digital technologies in urban planning, as well as in the field of housing and communal services within the framework of the national program “Digital Economy of the Russian Federation”. The advantages of using block-chain technology in the management of projects for the construction and operation of energy-efficient residential buildings have been studied in the paper. The application of the developed methods that meet the needs of participants in construction activities, as well as the housing and utilities sector, will improve the efficiency of not only the management system for the construction and operation of energy-efficient residential buildings, but also the overall effectiveness of the introduction of digital management in real estate. The proposed ABRIS software can be used in housing and communal services to optimize and track the expenditure of resources vital for a comfortable living of the population.Рассмотрен вопрос о переходе на цифровые технологии управления в сфере строительства и жилищно-коммунального хозяйства в России, а также в других странах. Разработана оптимизационная методика применения цифровой экономики на примере существующей системы управления недвижимостью – в микрорайоне «Столичный» города Ижевска (Удмуртская Республика, Российская Федерация). Описаны существующие и разработаны новые проекты цифровых технологий, внедрение которых повысит эффективность реализации строительства и эксплуатации жилых домов. Сформирована методика создания оптимизационной математической модели управления проектами строительства и эксплуатации энергоэффективных жилых домов. Даны предпосылки и схема совместного внедрения данной модели и цифровых технологий для улучшения качества строительства и эксплуатации жилых домов. В рамках национальной программы «Цифровая экономика Российской Федерации» предложена поэтапная методика внедрения цифровых технологий в градостроительную деятельность, а также в сферу жилищно-коммунального хозяйства. Рассмотрены преимущества использования технологии блокчейн в управлении проектами строительства и эксплуатации энергоэффективных жилых домов. Применение разработанных методик, удовлетворяющих запросам участников строительной деятельности и сферы жилищно-коммунального хозяйства, позволит повысить эффективность не только системы управления строительством и эксплуатацией энергоэффективных жилых домов, но и общую эффективность внедрения цифрового управления в сферу недвижимости. Предложенное программное обеспечение «АБРИС» может использоваться в жилищно-коммунальном хозяйстве для оптимизации и отслеживания расхода ресурсов, жизненно необходимых для комфортного проживания населения

    Studies of Biofilm Formation in Non-Pigmented and Plasmid-Deprived Mutants of <I>Yersinia pestis</I> on Biotic Surfaces, <I>in vivo</I> and <I>in vitro</I> Conditions

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    In non-pigmented and plasmid-deprived mutants – isogenic variants of highly virulent Yersinia pestis 231 strain – studied is the mechanism of biofilm formation on biotic surfaces, both in vitro (on the laboratory model of nematode Caenorhabdiitis elegans) and in vivo (inside the alimentary tract of Nosopsyllus laeviceps flea). It is determined that spontaneous loss of ability to form biofilms and generate pigmented colonies in the mutants is probably caused not only by the deletion of the whole chromosome pigmentation fragment, but also by a point(single base) mutation in structural hms operon. It is demonstrated that the absence of pCad, pFra or pPst plasmids does not have an impact on the ability of plasmid-deprived mutants to form biofilm on the cuticle of nematode C. elegans

    Modern Conception of the Control over the Abundance of Carriers and Vectors of Plague in the Territory of the Russian Federation

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    Disinfestation and deratization remain the main ways of non-specific disease prophylaxis in natural plague foci. Modern strategies, tactics, methods and means of control over carriers and vectors of plague and associated infectious diseases are selected with due consideration to epidemiological potential of territories, epizootic activity of a foci, peculiarities of population ecology of animals that are of a medical significance, preservation of biodiversity in natural ecosystems, and the requirements for human and natural environments protection from pollutants

    EEG-Based Functional Brain Networks: Does the Network Size Matter?

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    Functional connectivity in human brain can be represented as a network using electroencephalography (EEG) signals. These networks – whose nodes can vary from tens to hundreds – are characterized by neurobiologically meaningful graph theory metrics. This study investigates the degree to which various graph metrics depend upon the network size. To this end, EEGs from 32 normal subjects were recorded and functional networks of three different sizes were extracted. A state-space based method was used to calculate cross-correlation matrices between different brain regions. These correlation matrices were used to construct binary adjacency connectomes, which were assessed with regards to a number of graph metrics such as clustering coefficient, modularity, efficiency, economic efficiency, and assortativity. We showed that the estimates of these metrics significantly differ depending on the network size. Larger networks had higher efficiency, higher assortativity and lower modularity compared to those with smaller size and the same density. These findings indicate that the network size should be considered in any comparison of networks across studies
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