Glad Tidings and Grave Warnings: The Role of Advice on Cooperation in Public Goods Dilemmas With Value Uncertainty

We investigate how third-party advice on the estimated value of a public good acts as a dual-uncertainty reducing mechanism to encourage cooperation in a trust social dilemma. Experiment 1 finds that the valence of an advisor’s estimate affects cooperation behavior and that this advice effect is mediated by the level of trust that an individual has in fellow group members. Experiment 2 finds that when estimates about the value of the public good are mixed, trust in experts declines, and trust in other group members also declines. Experiment 3 finds that mixed valence estimates do not affect cooperation behavior when the majority of advisors are in consensus. In merging the social dilemma and advice-giving literatures, we show one way to navigate the dual-uncertainty problem when producing public goods and how independent, third-party advice can influence interpersonal relations among group members

Missile Aerodynamics for Ascent and Re-entry

Aerodynamic force and moment equations are developed for 6-DOF missile simulations of both the ascent phase of flight and a tumbling re-entry. The missile coordinate frame (M frame) and a frame parallel to the M frame were used for formulating the aerodynamic equations. The missile configuration chosen as an example is a cylinder with fixed fins and a nose cone. The equations include both the static aerodynamic coefficients and the aerodynamic damping derivatives. The inclusion of aerodynamic damping is essential for simulating a tumbling re-entry. Appended information provides insight into aerodynamic damping

PERFORMANCE STUDY OF K 2 CsSb PHOTOCATHODE INSIDE A DC HIGH VOLTAGE GUN*

Abstract In the past decade, there has been considerable interest in the generation of tens of mA average current in a photoinjector. Until recently, GaAs:Cs cathodes and K 2 CsSb cathodes have been tested successfully in DC and RF injectors respectively for this application. Our goal is to test the K 2 CsSb photocathode inside a DC gun. Since the multialkali cathode is a compound with constant characteristics over its entire thickness, we anticipate that the lifetime issues seen in GaAs:Cs due to surface damage by ion bombardment would be minimized. Hence successful operation of the K 2 CsSb cathode in a DC gun could lead to a relatively robust electron source capable of delivering ampere level currents. In order to test the performance of a K 2 CsSb cathode in a DC gun, we have designed and built a load lock system that allows the fabrication of the cathode at Brookhaven National Lab (BNL) and its testing at Jefferson Lab (JLab). In this paper, we will present the performance of the K 2 CsSb photocathode in the preparation chamber and in the DC gun

Eating As Treatment (EAT): A Stepped-Wedge, Randomized Controlled Trial of a Health Behavior Change Intervention Provided by Dietitians to Improve Nutrition in Patients With Head and Neck Cancer Undergoing Radiation Therapy (TROG 12.03)

Purpose: Malnutrition in head and neck cancer (HNC) treatment is common and associated with poorer morbidity and mortality outcomes. This trial aimed to improve nutritional status during radiation therapy (RT) using a novel method of training dietitians to deliver psychological techniques to improve nutritional behaviors in patients with HNC. Methods and Materials: This trial used a stepped-wedge, randomized controlled design to assess the efficacy of the Eating As Treatment (EAT) program. Based on motivational interviewing and cognitive behavioral therapy, EAT was designed to be delivered by oncology dietitians and integrated into their clinical practice. During control steps, dietitians provided treatment as usual, before being trained in EAT and moving into the intervention phase. The training was principles based and sought to improve behavior-change skills rather than provide specific scripts. Patients recruited to the trial (151 controls, 156 intervention) were assessed at 4 time points (the first and the final weeks of RT, and 4 and 12 weeks afterward). The primary outcome was nutritional status at the end of RT as measured by the Patient-Generated Subjective Global Assessment. Results: Patients who received the EAT intervention had significantly better scores on the primary outcome of nutritional status at the critical end-of-treatment time point (β = −1.53 [−2.93 to −.13], P =.03). Intervention patients were also significantly more likely than control patients to be assessed as well-nourished at each time point, lose a smaller percentage of weight, have fewer treatment interruptions, present lower depression scores, and report a higher quality of life. Although results were not statistically significant, patients who received the intervention had fewer and shorter unplanned hospital admissions. Conclusions: This trial is the first of its kind to demonstrate the effectiveness of a psychological intervention to improve nutrition in patients with HNC who are receiving RT. The intervention provides a means to ameliorate malnutrition and the important related outcomes and consequently should be incorporated into standard care for patients receiving RT for HNC

Methodology for Designing Structures to Withstand Extreme Environments: Performance Based Specifications

Existing guidelines in BS 8500 allow the selection of concrete mix based on variables such as compressive strength, maximum water to binder ratio, minimum cement content and minimum cover thickness. This approach does not guarantee the durability and expected performance of the concrete structure in a given environment. One alternative is to develop performance- based specifications that supplement the existing guidelines in BS 8500, by specifying the required performance of concrete in terms of measurable properties such as resistance to environmental penetrations. This paper demonstrates one of such methodology for developing performance-based specifications for concretes exposed to marine environments. Chloride ingress related durability problem being critical in a marine environment, the reliability and repeatability of the different test methods for assessing the rate of chloride ingress is discussed first. Furthermore, a numerical simulation model is used to explore the test data to obtain long-term chloride ingress trends. Based on this, guidelines for selecting appropriate concrete mixes for a marine exposure is presented and discussed

Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: An open label, non-randomized, controlled study

Additional file 1: Table S1. Detailed baseline characteristics for participants in the continuous care intervention (CCI) and usual care (UC) groups

ELISA-Based Measurement of Antibody Responses and PCR-Based Detection Profiles Can Distinguish between Active Infection and Early Clearance of Borrelia burgdorferi

Borrelia burgdorferi is a spirochetal bacterium that causes Lyme disease. These studies address whether current research methods using either ELISA to detect seroconversion to B. burgdorferi antigens or PCR quantification of bacterial DNA within tissues can accurately distinguish between a productive infection versus a B. burgdorferi exposure that is rapidly cleared by the innate responses. Mice receiving even minimal doses of live B. burgdorferi produced significantly more B. burgdorferi-specific IgM and IgG than groups receiving large inocula of heat-killed bacteria. Additionally, sera from mice injected with varied doses of killed B. burgdorferi recognized unique borrelial antigens compared to mice infected with live B. burgdorferi. Intradermal injection of killed B. burgdorferi resulted in rapid DNA clearance from skin, whereas DNA was consistently detected in skin inoculated with viable B. burgdorferi. These data indicate that both ELISA-based serological analyses and PCR-based methods of assessing B. burgdorferi infection clearly distinguish between an established infection with live bacteria and exposure to large numbers of bacteria that are promptly cleared by the innate responses