Loading and release of internally self-assembled emulsions embedded in a magnetic hydrogel

We have investigated drug loading and release from thermosensitive gel emulsions with external triggering by an alternating magnetic field (AMF) for on-demand drug delivery. Superparamagnetic iron oxide nanoparticles dispersed in gel emulsions were used to study the loading and release capabilities, with the stable nitroxide radical 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) serving as the model drug. AMF activation gave similar results to temperature activation in a water bath at 37 C, showing that the principal effect of the AMF is a temperature increase without burst release. These results suggest that the system could play an important role in the development of advanced drug delivery

Optical spectroscopy on monomeric and polymeric 1:1 fulleride salts

We compare infrared spectra of the C-60(-) monoanion in different solid-state structures with each other as well with that of the neutral molecule. We relate the shift and splitting of the T-u infrared modes to the strength and anisotropy of electron-phonon coupling in those environments