3D MODELING of A COMPLEX BUILDING: From MULTI-VIEW IMAGE FUSION to GOOGLE EARTH PUBLICATION

This paper presents a pipeline that aims at illustrating the procedure to realize a 3D model of a complex building integrating the UAV and terrestrial images and modifying the 3D model in order to publish to Google Earth in an interactive modality so as to provide better available models for visualization and use. The main steps of the procedure are the optimization of the UAV flight, the integration of the different UAV and ground floor images and the optimization of the model to be published to GE. The case study has been identified in a building, The Eremo di Santa Rosalia Convent in Sicily which hash more staggered elevations and located in the hills of the hinterland and of which, the online platform only indicate the position on Google Maps (GM) and Google Earth (GE) with a photo from above and a non-urban road whose GM path is not corresponding with the GE photo. The process highlights the integration of the models and showcases a workflow for the publication of the combined 3D model to the GE platform

Analysis of spread multi-jet VTOL aircraft in hover

An investigation of vertical takeoff and landing aircraft lift losses in hover was conducted to evaluate a method for a simplified test technique. Three flat plate models were tested to determine their usefulness in predicting hover characteristics by comparing results between plate and three-dimensional models. Data obtained for the plate models were correlated to three-dimensional results by the application of a geometrical equivalent height correction factor. The correlation of plate and tunnel models indicated that lift losses in ground effect were essentially independent of the efflux characteristics for the engine simulators

The Toxoplasma gondii plastid replication and repair enzyme complex, PREX

A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii and Plasmodium. The apicoplast contains multiple copies of a 35 kb genome, the replication of which is dependent upon nuclear-encoded proteins that are imported into the organelle. In P. falciparum an unusual multi-functional gene, pfprex, was previously identified and inferred to encode a protein with DNA primase, DNA helicase and DNA polymerase activities. Herein, we report the presence of a prex orthologue in T. gondii. The protein is predicted to have a bi-partite apicoplast targeting sequence similar to that demonstrated on the PfPREX polypeptide, capable of delivering marker proteins to the apicoplast. Unlike the P. falciparum gene that is devoid of introns, the T. gondii prex gene carries 19 introns, which are spliced to produce a contiguous mRNA. Bacterial expression of the polymerase domain reveals the protein to be active. Consistent with the reported absence of a plastid in Cryptosporidium species, in silico analysis of their genomes failed to demonstrate an orthologue of prex. These studies indicate that prex is conserved across the plastid-bearing apicomplexans and may play an important role in the replication of the plastid genome

HOW ARE CROP YIELDS DISTRIBUTED?

Six popular crop yield distributions are compared to determine which best describes yield fluctuations out-of-sample. For 183 crop and county combinations, each distribution is estimated and ranked according to its log-likelihood function observed at out-of-sample observations. A semiparametric model dominates the contest for most crops and counties, likely due to its flexibility and treatment of heteroskedasticity. Most other models ranked lower because their variance equation performed poorly out-of-sample.Crop Production/Industries,

Induced encystment improves resistance to preservation and storage of Acanthamoeba castellanii

Several conditions that allow the preservation, storage and rapid, efficient recovery of viable Acanthamoeba castellanii organisms were investigated. The viability of trophozoites (as determined by time to confluence) significantly declined over a period of 12 months when stored at −70°C using dimethyl sulfoxide (DMSO; 5 or 10%) as cryopreservant. As A. castellanii are naturally capable of encystment, studies were undertaken to determine whether induced encystment might improve the viability of organisms under a number of storage conditions. A. castellanii cysts stored in the presence of Mg2+ at 4°C remained viable over the study period, although time to confluence was increased from approximately 8 days to approximately 24 days over the 12-month period. Storage of cysts at −70°C with DMSO (5 or 10%) or 40% glycerol, but not 80% glycerol as cryopreservants increased their viability over the 12-month study period compared with those stored at room temperature. Continued presence of Mg2+ in medium during storage had no adverse effects and generally improved recovery of viable organisms. The present study demonstrates that A. castellanii can be stored as a non-multiplicative form inexpensively, without a need for cryopreservation, for at least 12 months, but viability is increased by storage at −70°C

The effect of Mach number on unstable disturbances in shock/boundary-layer interactions

The effect of Mach number on the growth of unstable disturbances in a boundary layer undergoing a strong interaction with an impinging oblique shock wave is studied by direct numerical simulation and linear stability theory (LST). To reduce the number of independent parameters, test cases are arranged so that both the interaction location Reynolds number (based on the distance from the plate leading edge to the shock impingement location for a corresponding inviscid flow) and the separation bubble length Reynolds number are held fixed. Small-amplitude disturbances are introduced via both white-noise and harmonic forcing and, after verification that the disturbances are convective in nature, linear growth rates are extracted from the simulations for comparison with parallel flow LST and solutions of the parabolized stability equations (PSE). At Mach 2.0, the oblique modes are dominant and consistent results are obtained from simulation and theory. At Mach 4.5 and Mach 6.85, the linear Navier-Stokes results show large reductions in disturbance energy at the point where the shock impinges on the top of the separated shear layer. The most unstable second mode has only weak growth over the bubble region, which instead shows significant growth of streamwise structures. The two higher Mach number cases are not well predicted by parallel flow LST, which gives frequencies and spanwise wave numbers that are significantly different from the simulations. The PSE approach leads to good qualitative predictions of the dominant frequency and wavenumber at Mach 2.0 and 4.5, but suffers from reduced accuracy in the region immediately after the shock impingement. Three-dimensional Navier-Stokes simulations are used to demonstrate that at finite amplitudes the flow structures undergo a nonlinear breakdown to turbulence. This breakdown is enhanced when the oblique-mode disturbances are supplemented with unstable Mack modes

Intrapartum epidural analgesia and breastfeeding: a prospective cohort study

BACKGROUND Anecdotal reports suggest that the addition of fentanyl (an opioid) to epidural analgesia for women during childbirth results in difficulty establishing breastfeeding. The aim of this paper is to determine any association between epidural analgesia and 1) breastfeeding in the first week postpartum and 2) breastfeeding cessation during the first 24 weeks postpartum. METHODS A prospective cohort study of 1280 women aged > or = 16 years, who gave birth to a single live infant in the Australian Capital Territory in 1997 was conducted. Women completed questionnaires at weeks 1, 8, 16 and 24 postpartum. Breastfeeding information was collected in each of the four surveys and women were categorised as either fully breastfeeding, partially breastfeeding or not breastfeeding at all. Women who had stopped breastfeeding since the previous survey were asked when they stopped. RESULTS In the first week postpartum, 93% of women were either fully or partially breastfeeding their baby and 60% were continuing to breastfeed at 24 weeks. Intrapartum analgesia and type of birth were associated with partial breastfeeding and breastfeeding difficulties in the first postpartum week (p < 0.0001). Analgesia, maternal age and education were associated with breastfeeding cessation in the first 24 weeks (p < 0.0001), with women who had epidurals being more likely to stop breastfeeding than women who used non-pharmacological methods of pain relief (adjusted hazard ratio 2.02, 95% CI 1.53, 2.67). CONCLUSION Women in this cohort who had epidurals were less likely to fully breastfeed their infant in the few days after birth and more likely to stop breastfeeding in the first 24 weeks. Although this relationship may not be causal, it is important that women at higher risk of breastfeeding cessation are provided with adequate breastfeeding assistance and support.Christine Roberts is supported by a National Health and Medical Research Council (NHMRC) of Australia Public Health Practitioner Fellowship and Siranda Torvaldsen is supported by a NHMRC Australian Research Training Fellowship. The cohort study was supported by a project grant from The Canberra Hospital Private Practice Fund. Additional funding was provided by The Canberra Hospital Auxiliary, the Nurses' Board of the Australian Capital Territory, and the Australian Capital Territory Department of Health & Community Care

Regulation of vascular endothelial growth factor bioactivity in patients with acute lung injury

Background: Reduced bioactive vascular endothelial growth factor (VEGF) has been demonstrated in several inflammatory lung conditions including the acute respiratory distress syndrome (ARDS). sVEGFR-1, a soluble form of VEGF-1 receptor, is a potent natural inhibitor of VEGF. We hypothesised that sVEGFR-1 plays an important role in the regulation of the bioactivity of VEGF within the lung in patients with ARDS. Methods: Forty one patients with ARDS, 12 at risk of developing ARDS, and 16 normal controls were studied. Bioactive VEGF, total VEGF, and sVEGFR-1 were measured by ELISA in plasma and bronchoalveolar lavage (BAL) fluid. Reverse transcriptase polymerase chain reaction for sVEGFR-1 was performed on BAL cells. Results: sVEGFR-1 was detectable in the BAL fluid of 48% (20/41) of patients with early ARDS (1.4– 54.8 ng/ml epithelial lining fluid (ELF)) compared with 8% (1/12) at risk patients (p = 0.017) and none of the normal controls (p = 0.002). By day 4 sVEGFR-1 was detectable in only 2/18 ARDS patients (p = 0.008). Patients with detectable sVEGFR-1 had lower ELF median (IQR) levels of bioactive VEGF than those without detectable sVEGFR-1 (1415.2 (474.9–3192) pg/ml v 4761 (1349–7596.6) pg/ml, median difference 3346 pg/ml (95% CI 305.1 to 14711.9), p = 0.016), but there was no difference in total VEGF levels. BAL cells expressed mRNA for sVEGFR-1 and produced sVEGFR-1 protein which increased following incubation with tumour necrosis factor a. Conclusion: This study shows for the first time the presence of sVEGFR-1 in the BAL fluid of patients with ARDS. This may explain the presence of reduced bioactive VEGF in patients early in the course of ARDS