Love at First Profile: An Experiment Exploring if Previously Incarcerated Individuals are Less Desirable While Online Dating

Incarceration is a rapidly increasing occurrence in the United States with more than 1.4 million people incarcerated and more than 2 million on some form of restricted confinement. While men are incarcerated at a much higher rate than women, women are still at a steady incline of incarceration as well. Also, people of color disproportionately make up a large number of those incarcerated while accounting for a small percentage of the general population. Previous research on people who have been incarcerated focuses on it affects education, employment, and marriage. Little research has attempted to explore how incarceration effects dating, a normal occurrence in the life course. In order to expand on existing research, this study utilizes experimental vignettes that manipulate the race, gender, and incarceration history of mock online dating profiles. Respondents were asked their attraction and relationship desirability toward the profile partner as well as other criminal justice related questions. Results found that an incarceration status does in fact cause lower rates in attraction and relationship desirability for both men and women respondents, albeit in different ways

Laissez-Faire Multiculturalism and Relational Embeddedness: Ethnic Precincts in Auckland

The rapid diversification of immigration to New Zealand post-1987 has made Auckland, as the nation’s key gateway city, both culturally and demographically superdiverse, and the location of considerable immigrant business development. We focus here on the development of ethnic precincts as the manifestation of this transformation of the cityscape. The neo-liberalism of the 1980s continues to prevail in the unwillingness of central and local government to recognise the ethnic/immigrant nature of such developments and there has been little in terms of either policy or resourcing to support or brand these precincts. As a consequence of this laissez-faire attitude, immigrants’ relational embeddedness tends to be privileged and ethnic-specific networks dictate the nature and location of ethnic precincts within a policy environment that stresses the importance of market processes and encourages small business development

Failure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression

Although depressed mood is a normal occurrence in response to adversity in all individuals, what distinguishes those who are vulnerable to major depressive disorder (MDD) is their inability to effectively regulate negative mood when it arises. Investigating the neural underpinnings of adaptive emotion regulation and the extent to which such processes are compromised in MDD may be helpful in understanding the pathophysiology of depression. We report results from a functional magnetic resonance imaging study demonstrating left-lateralized activation in the prefrontal cortex (PFC) when downregulating negative affect in nondepressed individuals, whereas depressed individuals showed bilateral PFC activation. Furthermore, during an effortful affective reappraisal task, nondepressed individuals showed an inverse relationship between activation in left ventrolateral PFC and the amygdala that is mediated by the ventromedial PFC (VMPFC). No such relationship was found for depressed individuals, who instead show a positive association between VMPFC and amygdala. Pupil dilation data suggest that those depressed patients who expend more effort to reappraise negative stimuli are characterized by accentuated activation in the amygdala, insula, and thalamus, whereas nondepressed individuals exhibit the opposite pattern. These findings indicate that a key feature underlying the pathophysiology of major depression is the counterproductive engagement of right prefrontal cortex and the lack of engagement of left lateral-ventromedial prefrontal circuitry important for the downregulation of amygdala responses to negative stimuli

Herschel-HIFI observations of H2O, NH3, and N2H+ toward high-mass starless and protostellar clumps identified by the Hi-GAL survey

Context. Our present understanding of high-mass star formation still remains very schematic. In particular, it is not yet clear how much of the difference between low-mass and high-mass star formation occurs during the earliest star formation phases. Aims. The chemical characteristics of massive cold clumps, and the comparison with those of their low-mass counterparts, could provide crucial clues about the exact role that chemistry plays in differentiating the early phases of low-mass and high-mass star formation. Water, in particular, is a unique probe of physical and chemical conditions in star-forming regions. Methods. Using the HIFI instrument of Herschel, we have observed the ortho−NH3 (10 −00 ) (572 GHz), ortho−H2 O (110 −101 ) (557 GHz), and N2 H+ (6−5) (559 GHz) lines toward a sample of high-mass starless and protostellar clumps selected from the Herschel Infrared Galactic Plane Survey (Hi-GAL). We compare our results to previous studies of low-mass and high-mass protostellar objects. Results. At least one of the three molecular lines was detected in 4 (out of 35) and 7 (out of 17) objects in the l = 59° and l = 30° galactic regions, respectively. All detected sources are protostellar. The water spectra are complex and consist of several kinematic components, identified through a Gaussian decomposition, and we detected inverse and regular P-Cygni profiles in a few sources. All water line profiles of the l = 59° region are dominated by a broad Gaussian emission feature, indicating that the bulk of the water emission arises in outflows. No such broad emission is detected toward the l = 30° objects. The ammonia line in some cases also shows line wings and an inverse P-Cygni profile, thus confirming that NH3 rotational transitions can be used to probe the dynamics of high-mass, star-forming regions. Both bolometric and water line luminosity increase with the continuum temperature. Conclusions. The higher water abundance toward the l = 59° sources, characterized by the presence of outflows and shocks, supports a scenario in which the abundance of this molecule is linked to the shocked gas. Various indicators suggest that the detected sources toward the l = 30° region are in a somewhat later evolutionary phase compared to the l = 59° field, although a firm conclusion is limited by the small number of observed sources. We find many similarities with studies carried out toward low-mass protostellar objects, but there are indications that the level of infall and turbulence in the high-mass protostars studied here could be significantly higher

Supporting the Development of Science Teacher Leaders - Where Do We Begin?

This conference paper was presented at the annual meeting of the Association for Science Teacher Education in Minneapolis, MN, in January 2011.Teacher leadership has been recognized as a necessary ingredient to support educational reform efforts. Leaders provide the needed expertise to ensure reforms are successful in promoting student learning. The overarching goal of the Leadership in Freshman Physics program is to support a cadre of teachers-leaders who will become advocates for “Physics First” by developing their knowledge of physics content and research-based pedagogy. In order to support teachers in developing the knowledge, skills, and dispositions for effective leadership, it is important to first understand their initial views of teacher leadership and their prior leadership experiences. In this paper we present results from the initial phase of our multi-year research study in which we examine teacher' past leadership experiences, definitions of teacher leadership, and views of themselves as leaders. Participants include a cohort of 36 teachers participating in the program, each of whom has committed to teaching a year‐long freshman physics course at their school. Our findings indicate teachers' definitions of leadership are relatively narrow, and often confined to formal leadership roles. Though teachers participate in numerous leadership activities, they don't explicitly consider these to be leadership. Implications for addressing teachers' conceptions through professional development are shared

Association between estrogen receptors and GATA3 in bladder cancer: a systematic review and meta-analysis of their clinicopathological significance

Background: Estrogen receptors alpha (ERα) and beta (ERβ) and the cooperating protein GATA-binding factor 3 (GATA3) have been implicated in bladder carcinogenesis and tumour progression. GATA3 and ER have been functionally linked in the establishment of luminal fate in breast tissue, but to date their relationship in bladder cancer has not been established. This information will be useful to advance diagnostic and prognostic markers. Aim: To determine the relationship between the expression of ERα, ERβ and GATA3 in bladder cancer, disclose their prognostic and diagnostic value and their association with clinicopathological characteristics. Methods: A comprehensive literature search in PubMed database was performed for all immunohistochemical studies of ERα, ERβ and/or GATA3 in bladder cancer patients. We selected eligible studies in accordance with the PRISMA guidelines and evaluated methodological quality and risk of bias based on quality criteria from the reporting recommendations for tumour MARKer (REMARK) prognostic studies. Risk of bias assessment was performed using Review Manager 5. R software was used for all statistical analysis, the packages used were meta and dmetar for the standard meta-analysis, and netmeta for the network meta-analysis. Results: Thirteen studies were eligible for ERα, 5 for ERβ and 58 for GATA3 meta-analysis. Low grade tumours showed significantly lower ERα expression. GATA3 was widely expressed in bladder tumours, especially urothelial carcinomas, with higher expression of GATA3 in low grade and low stage tumours. Data was insufficient to determine the prognostic value of either ERα or ERβ, but GATA3-positivity was associated with higher recurrence free survival. A negative correlation between ERα or ERβ positivity and GATA3 expression was disclosed. Additionally, several sources of heterogeneity were identified, which can be used to improve future studies. Conclusion: The clinicopathological value of ERα and ERβ was inconclusive due to low availability of studies using validated antibodies. Still, this meta-analysis supports GATA3 as good prognostic marker. On the contrary, ERα-positivity was associated to higher grade tumours; while ERα and ERβ were inversely correlated with GATA3 expression. Considering that it has previously been shown that bladder cancer cell lines have functional ERs, this suggests that ERα could be activated in less differentiated cells and independently of GATA3. Therefore, a comprehensive analysis of ERα and ERβ expression in BlaCa supported by complete patient clinical history is required for the identification of BlaCa subtypes and subgroups of patients expressing ERα, to investigate if they could benefit from treatment with hormonal therapy. Systematic Review Registration: Prospero, CRD42021226836.publishe

Dislocation Dynamics in an Anisotropic Stripe Pattern

The dynamics of dislocations confined to grain boundaries in a striped system are studied using electroconvection in the nematic liquid crystal N4. In electroconvection, a striped pattern of convection rolls forms for sufficiently high driving voltages. We consider the case of a rapid change in the voltage that takes the system from a uniform state to a state consisting of striped domains with two different wavevectors. The domains are separated by domain walls along one axis and a grain boundary of dislocations in the perpendicular direction. The pattern evolves through dislocation motion parallel to the domain walls. We report on features of the dislocation dynamics. The kinetics of the domain motion are quantified using three measures: dislocation density, average domain wall length, and the total domain wall length per area. All three quantities exhibit behavior consistent with power law evolution in time, with the defect density decaying as $t^{-1/3}$, the average domain wall length growing as $t^{1/3}$, and the total domain wall length decaying as $t^{-1/5}$. The two different exponents are indicative of the anisotropic growth of domains in the system.Comment: 8 figures: 7 jpeg and 1 pd

Ultrasound for diagnosing acute salpingitis: a prospective observational diagnostic study.

STUDY QUESTION: What are the diagnostic benefits of using ultrasound in patients with a clinical suspicion of acute salpingitis and signs of pelvic inflammatory disease (PID)? SUMMARY ANSWER: In patients with a clinical suspicion of acute salpingitis, the absence of bilateral adnexal masses at ultrasound decreases the odds of mild-to-severe acute salpingitis about five times, while the presence of bilateral adnexal masses increases the odds about five times. WHAT IS KNOWN ALREADY: PID is difficult to diagnose because the symptoms are often subtle and mild. The diagnosis is usually based on clinical findings, and these are unspecific. The sensitivity and specificity of ultrasound with regard to salpingitis have been reported in one study (n = 30) of appropriate design, where most patients had severe salpingitis (i.e. pyosalpinx) or tubo-ovarian abscess. STUDY DESIGN, SIZE, DURATION: This diagnostic test study included 52 patients fulfilling the clinical criteria of PID. Patients were recruited between October 1999 and August 2008. PARTICIPANTS/MATERIALS, SETTING, METHODS: The patients underwent a standardized transvaginal gray scale and Doppler ultrasound examination by one experienced sonologist (index test) before diagnostic laparoscopy by a laparoscopist blinded to the ultrasound results. The final diagnosis was determined by laparoscopy, histology of the endometrium and other histology where relevant (reference standard). MAIN RESULTS AND THE ROLE OF CHANCE: Of the 52 patients, 23 (44%) had a final diagnosis unrelated to genital infection, while the other 29 had cervicitis (n = 3), endometritis (n = 9) or salpingitis (n = 17; mild n = 4, moderate n = 8, severe, i.e. pyosalpinx n = 5). Bilateral adnexal masses and bilateral masses lying adjacent to the ovary were seen more often on ultrasound in patients with salpingitis than with other diagnoses (bilateral adnexal masses: 82 versus 17%, i.e. 14/17 versus 6/35, P = 0.000, positive likelihood ratio 4.8, negative likelihood ratio 0.22; bilateral masses adjacent to ovary: 65 versus 17%, i.e.11/17 versus 6/35, P = 0.001, positive likelihood ratio 3.8, negative likelihood ratio 0.42). In cases of salpingitis, the masses lying adjacent to the ovaries were on average 2-3 cm in diameter, solid (n = 14), unilocular cystic (n = 4), multilocular cystic (n = 3) or multilocular solid (n = 1), with thick walls and well vascularized at colour Doppler. In no case were the cogwheel sign or incomplete septae seen. All 13 cases of moderate or severe salpingitis were diagnosed with ultrasound (detection rate 100%, 95% confidence interval 78-100%) compared with 1 of 4 cases of mild salpingitis. Three of six cases of appendicitis, and two of two ovarian cysts were correctly diagnosed with ultrasound, and one case of adnexal torsion was suspected and then verified at laparoscopy. LIMITATIONS, REASONS FOR CAUTION: The sample size is small. This is explained by difficulties with patient recruitment. There are few cases of mild salpingitis, which means that we cannot estimate with any precision the ability of ultrasound to detect very early salpingitis. The proportion of cases with salpingitis of different grade affects the sensitivity and specificity of ultrasound, and the sensitivity and specificity that we report here are applicable only to patient populations similar to ours. WIDER IMPLICATIONS OF THE FINDINGS: The information provided by transvaginal ultrasound is likely to be of help when deciding whether or not to proceed with diagnostic laparoscopy in patients with symptoms and signs suggesting PID and, if laparoscopy is not performed, to select treatment and plan follow-up. STUDY FUNDING/COMPETING INTEREST(S): This work was supported by funds administered by Malmö University Hospital and two Swedish governmental grants (ALF-medel and Landstingsfinansierad Regional Forskning). The authors have no conflict of interest

Individual Differences in Amygdala and Ventromedial Prefrontal Cortex Activity are Associated with Evaluation Speed and Psychological Well-being

Using functional magnetic resonance imaging, we examined whether individual differences in amygdala activation in response to negative relative to neutral information are related to differences in the speed with which such information is evaluated, the extent to which such differences are associated with medial prefrontal cortex function, and their relationship with measures of trait anxiety and psychological well-being (PWB). Results indicated that faster judgments of negative relative to neutral information were associated with increased left and right amygdala activation. In the prefrontal cortex, faster judgment time was associated with relative decreased activation in a cluster in the ventral anterior cingulate cortex (ACC, BA 24). Furthermore, people who were slower to evaluate negative versus neutral information reported higher PWB. Importantly, higher PWB was strongly associated with increased activation in the ventral ACC for negative relative to neutral information. Individual differences in trait anxiety did not predict variation in judgment time or in amygdala or ventral ACC activity. These findings suggest that people high in PWB effectively recruit the ventral ACC when confronted with potentially aversive stimuli, manifest reduced activity in subcortical regions such as the amygdala, and appraise such information as less salient as reflected in slower evaluative speed