Insight into the Cycling Behaviour of Metal Anodes, Enabled by X-ray Tomography and Mathematical Modelling

This work tackles the methodological challenge of rationalizing symmetric-cell cycling data from a materials-science perspective, through experiment replication, mathematical modelling, and tomographic imaging. Specifically, we address Zn electrode cycling in alkaline electrolyte with and without adding tetrabutylammonium bromide (TBAB). This additive is known from literature, but its practical impact is jeopardized by lack of in-depth understanding of its behaviour. Electrochemical testing was carried out at practically relevant current densities and the effect of variations of operating conditions was taken into account. The physical chemistry underlying cell potential profiles, has been modelled mathematically, accounting for: electrokinetics, mass-transport, electrode shape change and passivation. In particular, we disclosed an unexpected joint effect of TBAB and current density on passivation time: tomography allowed to rationalise this behaviour in terms of precipitate morphology

The impact of ventral oral graft bulbar urethroplasty on sexual life

Objective: To evaluate the pre- and postoperative aspects of sexual life (SL) in patients with bulbar urethral stricture who underwent ventral oral graft urethroplasty. Methods: Between 2009 and 2010, 52 men (mean age 36 years) were enrolled in our prospective study to ascertain sexual disorders before and after surgery. The validated Male Sexual Health Questionnaire-Long Form (MSHQ-LF) was completed pre- and postoperatively; the unvalidated but adapted Post-Urethroplasty Sexual Questionnaire (PUSQ) was completed postoperatively. Data were compared using the non parametric Wilcoxon test. Results: Before urethroplasty, most of the patients reported sexual disorders, in particular reduced ejaculatory stream (85%); many of them (35%) feared the risk of a postoperative worsening in the quality of SL. After urethroplasty, nobody reported a worsened erection, while most of the patients noticed a significant improvement in erection, ejaculation, relationship with their partner, sexual activity, and desire. Modifications in the scrotoperineal sensitivity were reported by 42% and 15% noticed esthetic changes without impact on SL. All patients reported an improvement in quality of life (QOL) and were satisfied with the outcome of urethroplasty. Conclusion: Urethral stricture disease may be responsible for sexual disorders that have a significant impact upon SL. Patients confessed a marked anxiety tackling urethroplasty and declared that one of their deepest fears regarded a potential further deterioration in the quality of SL. At short-term follow-up, the minimally invasive ventral graft urethroplasty does not cause sexual complications, apart from the post-ejaculation dribbling. On the contrary, this technique showed to restore SL in all its aspects

Chromosomal control of non-gliadin proteins from the 70% ethanol extract of wheat endosperm

The non-gliadin fraction of the 70% ethanol extracts of compensated nulli-tetrasomics and ditelosomics of Triticum aestivum cv. Chinese Spring has been analyzed by combined electrofocusing and electrophoresis. Seventeen of the 21 protein map components of the euploid have been ascribed to eight chromosomes: 4A, 3BS, 6BS, 7BS, 3D, 4D, 5D and 7DS. The relationship of the different map components with other proteins previously associated with the same chromosomes is discusse

The Special LHC Interconnections: Technologies, Organization and Quality Control

In addition to the standard interconnections (IC) of the continuous cryostat of the Large Hadron Collider (LHC), there exists a variety of special ones related to specific components and assemblies, such as cryomagnets of the insertion regions, electrical feedboxes and superconducting links. Though they are less numerous, their specificities created many additional IC types, requiring a larger variety of assembly operations and quality control techniques, keeping very high standards of quality. Considerable flexibility and adaptability from all the teams involved (CERN staff, collaborating institutes, contractors) were the key points to ensure the success of this task. This paper first describes the special IC and presents the employed technologies which are generally adapted from the standard work. Then, the organization adopted for this non-repetitive work is described. Examples of non-conformities that were resolved are also discussed. Figures of merit in terms of quality and productivity are given and compared with standard IC wor

Ejaculation-sparing thulium laser enucleation of the prostate (ES-ThuLEP): outcomes on a large cohort

Purpose: To assess the effects of a new ejaculation-sparing thulium laser enucleation of the prostate (ES-ThuLEP) technique on sexual functions and micturition, in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH) and to evaluate how the surgical technique of ES-ThuLEP can lead to ejaculation preservation. Methods: A prospective study was carried out between January 2015 and January 2018 on patients with surgical indication for BPH, who wished to preserve ejaculation. The patients were treated with ES-ThuLEP and were evaluated before and 3 and 6 months after surgery. Three validated questionnaires (ICIQ-MLUTSsex, IIEF-5 and IPSS) were used to assess changes in ejaculation, erectile function and urinary symptoms. Uroflowmetry (Qmax and Qavg), post-void residual volume and voided volume were also evaluated, to assess micturition improvement. Patients with moderate to severe erectile dysfunction were excluded. Statistical analysis was performed with the Student\u2019s t test, Chi-square test and logistic regression analysis. Results: Two hundred and eighty three patients were enrolled. Ejaculation was spared in 203 and 219 patients at 3 and 6 months after surgery. No significant differences were observed between erectile function before and after surgery: baseline IIEF-5 = 16.2 \ub1 4.47 vs 16.7 \ub1 2.9 (p = 0.419) and 17.7 \ub1 3.2 (p = 0.410) at 3 and 6 months. Significant improvement in urinary symptoms was achieved: baseline IPSS = 19.4 \ub1 7.24 vs 5.8 \ub1 4.3 (p = 0.032) and 3.9 \ub1 4.1 (p = 0.029) at 3 and 6 months. Conclusion: ES-ThuLEP effectively preserved ejaculation in over two thirds of the patients without compromising micturition improvement or erectile function. ES-ThuLEP could be a valid treatment option for BPH in young and sexually active men

Contrast-enhanced mammography BI-RADS: a case-based approach to radiology reporting

Contrast-enhanced mammography (CEM) is a relatively recent diagnostic technique increasingly being utilized in clinical practice. Until recently, there was a lack of standardized reporting for CEM findings. However, this has changed with the publication of a supplement in the Breast Imaging Reporting and Data System (BI-RADS). A comprehensive understanding of CEM is essential for further enhancing its role in both screening and managing patients with breast malignancies. CEM can also be beneficial for problem-solving, improving the management of uncertain breast findings. Practitioners in this field should become more cognizant of how and when to employ this technique and interpret the various CEM findings. This paper aims to outline the key findings in the updated version of the BI-RADS specifically dedicated to CEM. Additionally, it will present some clinical cases commonly encountered in clinical practice. Critical relevance statement Standardized reporting and a thorough understanding of CEM findings are pivotal for advancing the role of CEM in screening and managing breast cancer patients. This standardization contributes significantly to integrating CEM as an essential component of daily clinical practice. Key points • A complete knowledge and understanding of the findings outlined in the new BI-RADS CEM are necessary for accurate reporting. • BI-RADS CEM supplement is intuitive and practical to use. • Standardization of the CEM findings enables more accurate patient management. Graphical Abstract: (Figure presented.

First Powering of the LHC Test String 2

String 2 is a full-size model of a regular cell in an LHC arc. In the first phase, three dipole magnets and two quadrupole magnets have been assembled in String 2 and commissioning started in April 2001. By the beginning of 2002 three pre-series dipole magnets will be added to complete the cell. As for its predecessor String 1, the facility was built to individually validate the LHC systems and to investigate their collective behaviour for normal operation with the magnets at a temperature of 1.9 K, during transients as well as during exceptional conditions. String 2 is a precious milestone before installation and commissioning of the first LHC sector (1/8 of the machine) in 2004, with respect to infrastructure, installation, tooling and assembly procedures, testing and commissioning of individual systems, as well as the global commissioning of the technical systems. This paper describes the commissioning, and retraces the first powering history

new energy sources in situ characterisation of fuel cell and supercapacitor components complementary studies using transmission fluorescence and photoelectron microscopy and imaging

Fuel cells and supercapacitors are electrochemical devices providing efficient and pollution-free production and transformation of electricity. Notwithstanding their environmental appeal, a host of materials-science problems – chiefly related to the limited durability of crucial functional components – are hindering their widespread application. The present knowledge of the relevant materials-science notion is mostly at the macroscopic and empirical trial-and-error level and the answers to many questions require much deeper scientific understanding of the origin of degradation processes. In this regard, the development and the implementation of appropriate methods for in-situ characterization of cell components at the functionally relevant length scales is highly required. Soft X-ray spectroscopies, such as X-ray absorption spectroscopy, X-ray emission (fluorescence) spectroscopy, resonant inelastic X-ray spectroscopy and X-ray photoelectron spectroscopy have been extensively employed for ex-situ characterization of materials used in electrochemical systems. Furthermore, adding spatial resolution capabilities by implementing proper optical solutions has opened unique opportunities for monitoring material changes and mass transport events occurring at submicron length scales. The input from these methods is providing correlative information about the status of the electrode surface and of the electrode/electrolyte interface and also of the processes occurring under operation conditions

The Commissioning of the LHC Test String 2

String 2 [1,2] is a full-size model of an LHC cell of the regular part of the arc. It is composed of six dipole magnets with their correctors, two short straight sections with their orbit and lattice corrector magnets, and a cryogenic distribution line running alongside the magnets. The commissioning of String 2 Phase 1, with one half-cell and the following quadrupole, has started in April 2001. As for String 1 [3], the facility was built to individually validate the LHC systems and to investigate their collective behaviour during normal operation (pump-down, cool-down and powering) as well as during exceptional conditions such as quenches. String 2 is a stepping stone towards the commissioning of the first sector (one eight of LHC) planned for 2004. It is expected to yield precious information on the infrastructures, the installation, the tooling and the procedures for the assembly, the testing and the commissioning of the individual systems, as well as the global commissioning of the technical systems. This paper describes the procedures followed for the commissioning and details the preparation for the first cool-down and for the powering

History of mammography: analysis of breast imaging diagnostic achievements over the last century

Breast cancer is the most common forms of cancer and a leading cause of mortality in women. Early and correct diagnosis is, therefore, essential to save lives. The development of diagnostic imaging applied to the breast has been impressive in recent years and the most used diagnostic test in the world is mammography, a low-dose X-ray technique used for imaging the breast. In the first half of the 20th century, the diagnosis was in practice only clinical, with consequent diagnostic delay and an unfavorable prognosis in the short term. The rise of organized mammography screening has led to a remarkable reduction in mortality through the early detection of breast malignancies. This historical review aims to offer a complete panorama of the development of mammography and breast imaging during the last century. Through this study, we want to understand the foundations of the pillar of radiology applied to the breast through to the most modern applications such as contrast-enhanced mammography (CEM), artificial intelligence, and radiomics. Understanding the history of the development of diagnostic imaging applied to the breast can help us understand how to better direct our efforts toward an increasingly personalized and effective diagnostic approach. The ultimate goal of imaging applied to the detection of breast malignancies should be to reduce mortality from this type of disease as much as possible. With this paper, we want to provide detailed documentation of the main steps in the evolution of breast imaging for the diagnosis of breast neoplasms; we also want to open up new scenarios where the possible current and future applications of imaging are aimed at being more precise and personalized