Wilms Tumour with Intracardiac Extension.

Wilms tumour or nephroblastoma is the most common renal tumour of in children. It accounts for 6% of all pediatric tumours and is the second most frequent intrabdominal solid organ tumour in children. Inferior vena cava (IVC) involvement by Wilms tumour occurs in 4-10% of patients and right atrium thrombus extension in less than 1%. Using a multidisciplinary approach, overall survival is excellent in Wilms tumour. We are presenting this case because Wilms tumour with right atrial thrombus is relatively rare and continues to remain a challenge for treating physicians

Tree Diversity, Biomass and Carbon Stock in Quartz Mined Area of Bilikal Hillock, hunasaekatte, Bhadravathi, Karnataka, South India

To learn about the abandoned mined area tree diversity, aboveground biomass and carbon stock a study was conducted in quartz mined Bilikal hillock area which is geographically adjacent to Umbalebylu 8 km to Bhadra wildlife sanctuary and 10 km of Kuvempu University. In the present study 0.14ha (350 m×4m) transect, we recorded 1527 individuals comprising 22 families among them Papilionaceae with 6 genera and 7 species, Combretaceae with 2 genera and 4 species followed by Rubiaceae with 3 genera and 3 species and Apocynaceae with 2 genera and 3 species. Based on girth class assessment nearly 1564 individuals comprising 1-10 cm had 559 individuals, the basal area was more within the girth class of 40-50 cm. But aboveground biomass and carbon stock were highest within the girth class of 20-30 cm. varying with species structure and girth class were a disturbed forest patch, the species composition needs management and restoration to retain the biodiversity intact to provide a niche for other co-species

Case Report: A child with acute lymphocytic leukaemia

No abstrac

Cognitive assessment of children with acute lymphoblastic leukemia: Preliminary findings

AIM: The objective of this study was to assess the cognitive functions of Indian children with acute lymphoblastic leukemia (ALL), periodically after initiation of treatment since prospective longitudinal research in this area on the Indian population has not been adequately documented. Unlike many western studies that have targeted survivors of ALL, we aimed to bring out the cognitive outcome after initiation of treatment. MATERIALS AND METHODS: The cognitive functions of 19 patients diagnosed to have ALL were assessed using standardized tests after induction chemotherapy, and periodically thereafter following the second course of treatment comprising central nervous system-directed radiotherapy, and chemotherapy using intrathecal methotrexate. RESULTS: The study found a statistically significant decline in the intelligence quotient and a deficit in the cognitive function of analytical reasoning. CONCLUSION: This preliminary study supports findings of an earlier Indian study and many studies conducted in the west. Since the life expectancy of these children has increased and most of them have long-term survival, and even cure, we suggest that identifying and managing children with cognitive difficulties are important in the rehabilitation of these children

Wilms Tumour with Intracardiac Extension

Wilms tumour or nephroblastoma is the most common renal tumour of in children. It accounts for 6% of all pediatric tumours and is the second most frequent intrabdominal solid organ tumour in children. Inferior vena cava (IVC) involvement by Wilms tumour occurs in 4-10% of patients and right atrium thrombus extension in less than 1%. Using a multidisciplinary approach, overall survival is excellent in Wilms tumour. We are presenting this case because Wilms tumour with right atrial thrombus is relatively rare and continues to remain a challenge for treating physician

Acute promyelocytic leukemia with unusual karyotype

Acute myeloid leukemia (AML-M3) is associated with the translocation t(15;17)(q22;q12-21) which disrupts the retinoic acid receptor alpha (RARA) gene on chromosome 17 and the PML gene on chromosome 15. We report a two-year-old patient with AML-M3 without the usual translocation t(15;17). Cytogenetic studies demonstrated normal appearance of chromosome 15 while the abnormal 17 homologue was apparently a derivative 17, der(17)(17qter-cen-q21:), the rearrangement distinctly shows deletion at 17q21 band and the morphology corresponding to an iso chromosome i(17q-). This case report is a rare cytogenetic presentation of acute promyelocytic leukemia (APML)