Phytochemical and biological properties of ajuga decumbens (labiatae): A review

Ajuga decumbens Thunb is a member of Labiatae family and widespread in China, Korea and Japan. This plant possesses diverse pharmacological activities, such as anti-inflammatory, antitumor, antibacterial, antiviral, cytotoxic, as well as insecticidal activities. Several compounds have been isolated from A. decumbens, which display a wide spectrum of biological and pharmacological activities. Hence, it would be useful to review current literature for available pharmacological activities of the plant as well as its active ingredients

Differences in Health-Related Quality of Life and Its Associated Factors Among Older Adults in Urban and Rural Areas

Jiachi Zhang,1 Shujuan Xiao,1,2 Lei Shi,1 Yaqing Xue,1,2 Xiao Zheng,1,2 Fang Dong,1 Benli Xue,1 Chichen Zhang1,3,4 1School of Health Management, Southern Medical University, Guangzhou, People’s Republic of China; 2School of Public Health, Southern Medical University, Guangzhou, People’s Republic of China; 3Department of Health Management, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 4Institute of Health Management, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence: Chichen Zhang, School of Health Management, Southern Medical University, No. 1023 Shatai South Road, Baiyun District, Guangzhou, 510515, People’s Republic of China, Tel +86-20-61648756, Email [email protected]: Urban-rural health disparity is one of the most prominent challenges in China today. The goal of this study is to find differences in health-related quality of life (HRQoL) and its associated factors among older people in urban and rural areas.Methods: A multi-stage stratified sampling method was conducted in Shanxi Province, with a total of 3250 older adults participated in this cross-sectional survey. HRQoL was assessed using the Chinese version of the EQ-5D-5L. Tobit regression models were employed to identify associated factors for HRQoL.Results: The mean EQ-5D utility score of the total sample was 0.87± 0.23, with a statistically significant difference observed between urban (0.89 ± 0.22) and rural areas (0.86 ± 0.23). Obesity (Coe=− 0.10, p=0.021) and nutrition awareness (Coe=− 0.14, p=0.009) were two unique associated factors to rural older adults’ HRQoL. While, age (Urban: Coe=0.13, p=0.001; Rural: Coe=− 0.019, p< 0.001), socioeconomic status (Urban: Coe=0.13, p< 0.001; Rural: Coe=0.14, p< 0.001), number of chronic non-communicable diseases (Urban: Coe=− 0.20, p< 0.001; Rural: Coe=− 0.15, p< 0.001), sleep quality (Urban: Coe=− 0.22, p< 0.001; Rural: Coe=0.15, p< 0.001) and daytime sleepiness (Urban: Coe=− 0.13, p< 0.001; Rural: Coe=− 0.13, p< 0.001) were found to be associated with HRQoL regardless of the residential area.Conclusion: This study suggested that rural older adults are facing HRQoL disadvantages compared to those in urban area. Accordingly, more attention should be devoted to rural older adults’ HRQoL, particularly to the unique factors like body weight and nutrition awareness. Targeted policies and interventions should be implemented to improve HRQoL and bridge the urban-rural HRQoL gap.Keywords: health-related quality of life, HRQoL, older adults, urban and rural, health managemen

Hybrid nature of 0846+51W1: a BL Lac object with a narrow line Seyfert 1 nucleus

We have found a NLS1 nucleus in the extensively studied eruptive BL Lac, 0846+51W1, out of a large sample of NLS1 compiled from the spectroscopic dataset of SDSS DR1. Its optical spectrum can be well decomposed into three components, a power law component from the relativistic jet, a stellar component from the host galaxy, and a component from a typical NLS1 nucleus. The emission line properties of 0846+51W1, FWHM(Hbeta) ~ 1710 km s^-1 and [OIII]5007/Hbeta ~ 0.32 when it was in faint state, fulfil the conventional definition of NLS1. Strong FeII emission is detected in the SDSS spectrum, which is also typical of NLS1s. We try to estimate its central black hole mass using various techniques and find that 0846+51W1 is very likely emitting at a few times 10% L_Edd. We speculate that Seyfert-like nuclei, including NLS1s, might be concealed in a significant fraction of BL Lacs but have not been sufficiently explored due to the fact that, by definition, the optical-UV continuum of such kind of objects are often overwhelmed by the synchrotron emission.Comment: ChJAA accepte

Anemia in Heart Failure: A Perspective from 20-Year Bibliometric Analysis

Qiwen Yang,1,2,&ast; Tairan Dong,1,&ast; Diyang Lyu,2 Donghua Xue,1,2 Rui Zhuang,2 Liyong Ma,2 Lijing Zhang2 1Graduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lijing Zhang, Department of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China, Email [email protected] & Objective: Anemia in patients with heart failure (HF) is a growing concern. However, there has no bibliometric analysis in this area up to now. The aim of this study is to explore the status and trends in the field of anemia in HF through the bibliometric analysis, and to provide an outlook on future research.Methods: We retrieved publications from the Web of Science Core Collection database, and the following data analysis and visualization tools were utilized to perform data processing, statistical computing and graphics generation: VOSviewer (v.1.6.18), CiteSpace (v.6.2 R5), Scimago Graphica (v.1.0.36), Biblimatrix and Microsoft Excel.Results: We identified a total of 3490 publications from 2004 to 2023. The publications in the field of anemia in HF are growing steadily. The United States, the United Kingdom, and Italy were the leading countries in this area. Stefan D Anker, as the most influential author, held the most total citations and publications. Harvard University was the most productive institution in this area. The European Journal of Heart Failure had published the most papers. Through the analysis of co-citations, 14 major clusters based on cluster labels were identified. Keyword analysis showed that mortality, outcome, prevalence, and risk were the most frequent keywords, and the potential research hotspots in the future will be intravenous iron and iron deficiency.Conclusion: This study provides a comprehensive analysis of countries, authors, institutions, journals, co-cited references, and keywords in the field of anemia in HF through bibliometric analysis and data visualization. The status, hotspots and future trends in this field offer a reference for in-depth research. Further studies are necessary in the future to broaden the spectrum of research in this field, to evaluate comprehensive approaches to treating anemia in patients with HF, and to find rational targets for the management of anemia.Keywords: anemia, heart failure, hemoglobin, iron deficiency, bibliometric

Quantum controlled phase gate and cluster states generation via two superconducting quantum interference devices in a cavity

A scheme for implementing 2-qubit quantum controlled phase gate (QCPG) is proposed with two superconducting quantum interference devices (SQUIDs) in a cavity. The gate operations are realized within the two lower flux states of the SQUIDs by using a quantized cavity field and classical microwave pulses. Our scheme is achieved without any type of measurement, does not use the cavity mode as the data bus and only requires a very short resonant interaction of the SQUID-cavity system. As an application of the QCPG operation, we also propose a scheme for generating the cluster states of many SQUIDs.Comment: 4 pages, resumitte