484 research outputs found
Bonding-Compatible Corrosion Inhibitor for Rinsing Metals
A corrosion-inhibiting mixture of compounds has been developed for addition to the water used to rinse metal parts that have been cleaned with aqueous solutions in preparation for adhesive bonding of the metals to rubber and rubber-like materials. Prior to the development of this corrosion inhibitor, the parts (made, variously, of D6AC steel and 7075-T73 aluminum) were rinsed by deionized water, which caused corrosion in some places on the steel parts especially in such occluded places as sealing surfaces and threaded blind holes. An integral part of the particular cleaning process is the deposition of a thin layer of silicates and silane primers that increase the strength of the adhesive bond. The corrosion inhibitor is formulated, not only to inhibit corrosion of both D6AC steel and 7075- T73 aluminum, but also to either increase or at least not reduce the strength of the adhesive bond to be formed subsequently. The corrosion inhibitor is a mixture of sodium silicate and sodium tetraborate. The sodium silicate functions as both a corrosion inhibitor and a bond-strength promoter in association with the silane primers. The sodium tetraborate buffers the rinse solution at the optimum pH and functions as a secondary corrosion inhibitor for the steel. For a given application, the concentrations of sodium silicate and sodium tetraborate must be chosen in a compromise among the needs to inhibit corrosion of steel, inhibit corrosion of aluminum, and minimize cosmetic staining of both steel and aluminum. Concentrations of sodium silicate in excess of 150 parts of silicon per million parts of solution (ppm Si) have been determined to enhance inhibition of corrosion; unfortunately, because of the alkalinity of sodium silicate, even a small concentration can raise the pH of the rinse solution to such a level that aluminum becomes corroded despite the inhibiting effect. The pH of a solution that contains a high concentration of sodium silicate can be decreased by adding sodium tetraborate. On the other hand, the addition of sodium tetraborate increases the concentration of dissolved solids to such a high level that cosmetic staining becomes an issue
The Effects of Silicone Contamination on Bond Performance of Various Bond Systems
The sensitivity to silicone contamination of a wide variety of adhesive bond systems is discussed. Generalizations regarding factors that make some bond systems more sensitive to contamination than others are inferred and discussed. The effect of silane adhesion promoting primer on the contamination sensitivity of two epoxy/steel bond systems is also discussed
Modeling Amyloid Beta Peptide Insertion into Lipid Bilayers
Inspired by recent suggestions that the Alzheimer's amyloid beta peptide (A
beta) can insert into cell membranes and form harmful ion channels, we model
insertion of the 40 and 42 residue forms of the peptide into cell membranes
using a Monte Carlo code which is specific at the amino acid level. We examine
insertion of the regular A-beta peptide as well as mutants causing familial
Alzheimer's disease, and find that all but one of the mutants change the
insertion behavior by causing the peptide to spend more simulation steps in
only one leaflet of the bilayer. We also find that A-beta 42, because of the
extra hydrophobic residues relative to A-beta 40, is more likely to adopt this
conformation than A-beta 40 in both wild-type and mutant forms. We argue
qualitatively why these effects happen. Here, we present our results and
develop the hypothesis that this partial insertion increases the probability of
harmful channel formation. This hypothesis can partly explain why these
mutations are neurotoxic simply due to peptide insertion behavior. We further
apply this model to various artificial A-beta mutants which have been examined
experimentally, and offer testable experimental predictions contrasting the
roles of aggregation and insertion with regard to toxicity of A-beta mutants.
These can be used through further experiments to test our hypothesis.Comment: 14 pages; 8 figures; 2nd revisio
Seeded x-ray free-electron laser generating radiation with laser statistical properties
The invention of optical lasers led to a revolution in the field of optics
and even to the creation of completely new fields of research such as quantum
optics. The reason was their unique statistical and coherence properties. The
newly emerging, short-wavelength free-electron lasers (FELs) are sources of
very bright coherent extreme-ultraviolet (XUV) and x-ray radiation with pulse
durations on the order of femtoseconds, and are presently considered to be
laser sources at these energies. Most existing FELs are highly spatially
coherent but in spite of their name, they behave statistically as chaotic
sources. Here, we demonstrate experimentally, by combining Hanbury Brown and
Twiss (HBT) interferometry with spectral measurements that the seeded XUV FERMI
FEL-2 source does indeed behave statistically as a laser. The first steps have
been taken towards exploiting the first-order coherence of FELs, and the
present work opens the way to quantum optics experiments that strongly rely on
high-order statistical properties of the radiation.Comment: 24 pages, 10 figures, 37 reference
The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions
The L55P transthyretin (TTR) familial amyloid polyneuropathy-associated variant is distinct from the other TTR variants studied to date and the wild-type protein in that the L55P tetramer can dissociate to the monomeric amyloidogenic intermediate and form fibril precursors under physiological conditions (pH 7.0, 37 degrees C). The activation barrier associated with L55P-TTR tetramer dissociation is lower than the barrier for wild-type transthyretin dissociation, which does not form fibrils under physiological conditions. The L55P-TTR tetramer is also very sensitive to acidic conditions, readily dissociating to form the monomeric amyloidogenic intermediate between pH 5.5-5.0 where the wild-type TTR adopts a nonamyloidogenic tetrameric structure. The formation of the L55P monomeric amyloidogenic intermediate involves subtle tertiary structural changes within the beta-sheet rich subunit as discerned from Trp fluorescence, circular dichroism analysis, and ANS binding studies. The assembly of the L55P-TTR amyloidogenic intermediate at physiological pH (pH 7.5) affords protofilaments that elongate with time. TEM studies suggest that the entropic barrier associated with filament assembly (amyloid fibril formation) is high in vitro, amyloid being defined by the laterally assembled four filament structure observed by Blake upon isolation of "fibrils" from the eye of a FAP patient. The L55P-TTR protofilaments formed in vitro bind Congo red and thioflavin T (albeit more weakly than the fibrils produced at acidic pH), suggesting that the structure observed probably represents an amyloid precursor. The structural continuum from misfolded monomer through protofilaments, filaments, and ultimately fibrils must be considered as a possible source of pathology associated with these diseases
Spin Wave Theory of Double Exchange Ferromagnets
We construct the 1/S spin-wave expansion for double exchange ferromagnets at
T=0. It is assumed that the value of Hund's rule coupling, J_H, is sufficiently
large, resulting in a fully saturated, ferromagnetic half-metallic ground
state. We evaluate corrections to the magnon dispersion law, and we also find
that, in contrast to earlier statements in the literature, magnon-electron
scattering does give rise to spin wave damping. We analyse the momentum
dependence of these quantities and discuss the experimental implications for
colossal magnetoresistance compounds.Comment: 4 pages, Latex-Revtex, 2 PostScript figures. Minor revisions,
references added. See also cond-mat/990921
Anomaly in Spin Excitation Spectrum of Double-Exchange Systems with Randomness
Spin excitation spectrum of the double-exchange model is studied in the
presence of randomness. Spin wave approximation in the ground state shows that
the randomness significantly modifies the spectrum from the cosine-like one in
the pure system to that with anomalies such as broadening, anti-crossing and
gap opening. The origin of anomalies is speculated to be modulation of
effective ferromagnetic coupling by the Friedel oscillation. These anomalies
qualitatively reproduce the spin excitation spectrum in colossal
magnetoresistance manganites whose Curie temperatures are relatively low. Our
results suggest that randomness control is an important notion to understand
effects of the A-site substitution which has previously been understood as the
bandwidth control.Comment: 4 pages including 3 figure
Three-body correlations in the Nagaoka state on the square lattice
A three-body scattering theory previously proposed by one of the present
authors is developed to be applied to the saturated ferromagnetic state in the
two-dimensional Hubbard model. The single-particle Green's function is
calculated by taking account of the multiple scattering between two electrons
and one hole. Several limiting cases are discussed and the relation to the
variational principle is examined. The importance of the three-body correlation
is demonstrated in comparison with the results of the ladder approximation. A
possible phase boundary for the Nagaoka ground state is presented for the
square lattice, which improves the previous variational results.Comment: 13 pages, 8 Postscript figures, submitted to Phys.Rev.
Catalysis in Real Time Using X-Ray Lasers
We describe how the unique temporal and spectral characteristics of X-ray free-electron lasers (XFEL) can be utilized to follow chemical transformations in heterogeneous catalysis in real time. We highlight the systematic study of CO oxidation on Ru(0001), which we initiate either using a femtosecond pulse from an optical laser or by activating only the oxygen atoms using a THz pulse. We find that CO is promoted into an entropy-controlled precursor state prior to desorbing when the surface is heated in the absence of oxygen, whereas in the presence of oxygen, CO desorbs directly into the gas phase. We monitor the activation of atomic oxygen explicitly by the reduced split between bonding and antibonding orbitals as the oxygen comes out of the strongly bound hollow position. Applying these novel XFEL techniques to the full oxidation reaction resulted in the surprising observation of a significant fraction of the reactants at the transition state through the electronic signature of the new bond formation
- …