476 research outputs found

    Learning about knowledge: A complex network approach

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    This article describes an approach to modeling knowledge acquisition in terms of walks along complex networks. Each subset of knowledge is represented as a node, and relations between such knowledge are expressed as edges. Two types of edges are considered, corresponding to free and conditional transitions. The latter case implies that a node can only be reached after visiting previously a set of nodes (the required conditions). The process of knowledge acquisition can then be simulated by considering the number of nodes visited as a single agent moves along the network, starting from its lowest layer. It is shown that hierarchical networks, i.e. networks composed of successive interconnected layers, arise naturally as a consequence of compositions of the prerequisite relationships between the nodes. In order to avoid deadlocks, i.e. unreachable nodes, the subnetwork in each layer is assumed to be a connected component. Several configurations of such hierarchical knowledge networks are simulated and the performance of the moving agent quantified in terms of the percentage of visited nodes after each movement. The Barab\'asi-Albert and random models are considered for the layer and interconnecting subnetworks. Although all subnetworks in each realization have the same number of nodes, several interconnectivities, defined by the average node degree of the interconnection networks, have been considered. Two visiting strategies are investigated: random choice among the existing edges and preferential choice to so far untracked edges. A series of interesting results are obtained, including the identification of a series of plateaux of knowledge stagnation in the case of the preferential movements strategy in presence of conditional edges.Comment: 18 pages, 19 figure

    Giant strongly connected component of directed networks

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    We describe how to calculate the sizes of all giant connected components of a directed graph, including the {\em strongly} connected one. Just to the class of directed networks, in particular, belongs the World Wide Web. The results are obtained for graphs with statistically uncorrelated vertices and an arbitrary joint in,out-degree distribution P(ki,ko)P(k_i,k_o). We show that if P(ki,ko)P(k_i,k_o) does not factorize, the relative size of the giant strongly connected component deviates from the product of the relative sizes of the giant in- and out-components. The calculations of the relative sizes of all the giant components are demonstrated using the simplest examples. We explain that the giant strongly connected component may be less resilient to random damage than the giant weakly connected one.Comment: 4 pages revtex, 4 figure

    Passive and catalytic antibodies and drug delivery

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    Antibodies are one of the most promising components of the biotechnology repertoire for the purpose of drug delivery. On the one hand, they are proven agents for cell-selective delivery of highly toxic agents in a small but expanding number of cases. This technology calls for the covalent attachment of the cytotoxin to a tumor-specific antibody by a linkage that is reversible under appropriate conditions (antibody conjugate therapy, ACT —"passive delivery”). On the other hand, the linker cleavage can be accomplished by a protein catalyst attached to the tumor-specific antibody ("catalytic delivery”). Where the catalyst is an enzyme, this approach is known as antibody-directed enzyme prodrug therapy (ADEPT). Where the transformation is brought about by a catalytic antibody, it has been termed antibody-directed abzyme prodrug therapy (ADAPT). These approaches will be illustrated with emphasis on how their demand for new biotechnology is being realized by structure-based protein engineerin

    Optical Aharonov-Bohm effect in stacked type-II quantum dots

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    Excitons in vertically stacked type-II quantum dots experience the topological magnetic phase and demonstrate the Aharonov-Bohm oscillations in the emission intensity. Photoluminescence of vertically stacked ZnTe/ZnSe quantum dots is measured in magnetic fields up to 31 T. The Aharonov-Bohm oscillations are found in the magnetic-field dependence of emission intensity. The positions of the peaks of the emission intensity are in a good agreement with numerical simulations of excitons in stacked quantum dots.Comment: 15 page

    Theoretical approach and impact of correlations on the critical packet generation rate in traffic dynamics on complex networks

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    Using the formalism of the biased random walk in random uncorrelated networks with arbitrary degree distributions, we develop theoretical approach to the critical packet generation rate in traffic based on routing strategy with local information. We explain microscopic origins of the transition from the flow to the jammed phase and discuss how the node neighbourhood topology affects the transport capacity in uncorrelated and correlated networks.Comment: 6 pages, 5 figure

    Single and vertically coupled type II quantum dots in a perpendicular magnetic field: exciton groundstate properties

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    The properties of an exciton in a type II quantum dot are studied under the influence of a perpendicular applied magnetic field. The dot is modelled by a quantum disk with radius RR, thickness dd and the electron is confined in the disk, whereas the hole is located in the barrier. The exciton energy and wavefunctions are calculated using a Hartree-Fock mesh method. We distinguish two different regimes, namely d<<2Rd<<2R (the hole is located at the radial boundary of the disk) and d>>2Rd>>2R (the hole is located above and below the disk), for which angular momentum (l)(l) transitions are predicted with increasing magnetic field. We also considered a system of two vertically coupled dots where now an extra parameter is introduced, namely the interdot distance dzd_{z}. For each lhl_{h} and for a sufficient large magnetic field, the ground state becomes spontaneous symmetry broken in which the electron and the hole move towards one of the dots. This transition is induced by the Coulomb interaction and leads to a magnetic field induced dipole moment. No such symmetry broken ground states are found for a single dot (and for three vertically coupled symmetric quantum disks). For a system of two vertically coupled truncated cones, which is asymmetric from the start, we still find angular momentum transitions. For a symmetric system of three vertically coupled quantum disks, the system resembles for small dzd_{z} the pillar-like regime of a single dot, where the hole tends to stay at the radial boundary, which induces angular momentum transitions with increasing magnetic field. For larger dzd_{z} the hole can sit between the disks and the lh=0l_{h}=0 state remains the groundstate for the whole BB-region.Comment: 11 pages, 16 figure

    An Exactly Solvable Anisotropic Directed Percolation Model in Three Dimensions

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    We solve exactly a special case of the anisotropic directed bond percolation problem in three dimensions, in which the occupation probability is 1 along two spatial directions, by mapping it to a five-vertex model. We determine the asymptotic shape of the ininite cluster and hence the direction dependent critical probability. The exponents characterising the fluctuations of the boundary of the wetted cluster in d-dimensions are related to those of the (d-2)-dimensional KPZ equation.Comment: 4 pages, RevTex, 4 figures. 1 reference added, minor change

    Sandpile Model with Activity Inhibition

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    A new sandpile model is studied in which bonds of the system are inhibited for activity after a certain number of transmission of grains. This condition impels an unstable sand column to distribute grains only to those neighbours which have toppled less than m times. In this non-Abelian model grains effectively move faster than the ordinary diffusion (super-diffusion). A novel system size dependent cross-over from Abelian sandpile behaviour to a new critical behaviour is observed for all values of the parameter m.Comment: 11 pages, RevTex, 5 Postscript figure

    Measurement report: In situ observations of deep convection without lightning during the tropical cyclone Florence 2018

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    Hurricane Florence was the sixth named storm in the Atlantic hurricane season 2018. It caused dozens of deaths and major economic damage. In this study, we present in situ observations of trace gases within tropical storm Florence on 2 September 2018, after it had developed a rotating nature, and of a tropical wave observed close to the African continent on 29 August 2018 as part of the research campaign CAFE Africa (Chemistry of the Atmosphere: Field Experiment in Africa) with HALO (High Altitude and LOng Range Research Aircraft). We show the impact of deep convection on atmospheric composition by measurements of the trace gases nitric oxide (NO), ozone (O3_{3}), carbon monoxide (CO), hydrogen peroxide (H2_{2}O2_{2}), dimethyl sulfide (DMS) and methyl iodide (CH3_{3}I) and by the help of color-enhanced infrared satellite imagery taken by GOES-16. While both systems, i.e., the tropical wave and the tropical storm, are deeply convective, we only find evidence for lightning in the tropical wave using both in situ NO measurements and data from the World Wide Lightning Location Network (WWLLN)
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