351 research outputs found

    The grasshopper, your sharecropper

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    Cover title.Includes bibliographical references

    Monoclonal Antibodies against the Drosophila Nervous System

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    A panel of 148 monoclonal antibodies directed against Drosophila neural antigens has been prepared by using mice immunized with homogenates of Drosophila tissue. Antibodies were screened immunohistochemically on cryostat sections of fly heads. A large diversity of staining patterns was observed. Some antigens were broadly distributed among tissues; others were highly specific to nerve fibers, neuropil, muscle, the tracheal system, cell nuclei, photoreceptors, or other structures. The antigens for many of the antibodies have been identified on immunoblots. Monoclonal antibodies that identify specific molecules within the nervous system should prove useful in the study of the molecular genetics of neural development

    Grasshopper control with sprays : Southwestern Missouri tests, 1955-1957

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    The bulletin reports work done on Department of Entomology research projects 286 and 369, Grasshopper Investigations--P. [3].Digitized 2007 AES.Includes bibliographical references (page 20)

    Strategies to mitigate bias from time recording errors in pharmacokinetic studies

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    Opportunistic pharmacokinetic (PK) studies have sparse and imbalanced clinical measurement data, and the impact of sample time errors is an important concern when seeking accurate estimates of treatment response. We evaluated an approximate Bayesian model for individualized pharmacokinetics in the presence of time recording errors (TREs), considering both a short and long infusion dosing pattern. We found that the long infusion schedule generally had lower bias in estimates of the pharmacodynamic (PD) endpoint relative to the short infusion schedule. We investigated three different design strategies for their ability to mitigate the impact of TREs: (i) shifting blood draws taken during an active infusion to the post-infusion period, (ii) identifying the best next sample time by minimizing bias in the presence of TREs, and (iii) collecting additional information on a subset of patients based on estimate uncertainty or quadrature-estimated variance in the presence of TREs. Generally, the proposed strategies led to a decrease in bias of the PD estimate for the short infusion schedule, but had a negligible impact for the long infusion schedule. Dosing regimens with periods of high non-linearity may benefit from design modifications, while more stable concentration-time profiles are generally more robust to TREs with no design modifications

    AOIPS water resources data management system

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    A geocoded data management system applicable for hydrological applications was designed to demonstrate the utility of the Atmospheric and Oceanographic Information Processing System (AOIPS) for hydrological applications. Within that context, the geocoded hydrology data management system was designed to take advantage of the interactive capability of the AOIPS hardware. Portions of the Water Resource Data Management System which best demonstrate the interactive nature of the hydrology data management system were implemented on the AOIPS. A hydrological case study was prepared using all data supplied for the Bear River watershed located in northwest Utah, southeast Idaho, and western Wyoming

    A Non-Pharmaceutical Approach to Chronic Pain: An OT’s Perspective

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    The following project was created for advocacy and education of occupational therapy\u27s role in chronic pain management. This project focuses on occupational therapist\u27s ability to utilize non-pharmaceutical interventions to manage chronic pain symptoms. The capstone outlines fitness-based exercises, aquatic therapy, ergonomics, adaptive equipment, and adaptive strategies by supporting their efficacy in recent literature. Occupational therapists possess invaluable skills that can impact the chronic pain community for the better. They can aid in the reduction of pain while increasing overall quality of life and independence. Occupational therapists are a much needed resource in chronic pain management.https://soar.usa.edu/otdcapstonespring2020/1012/thumbnail.jp

    Religion and Measles Vaccination in Indonesia, 1991-2017

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    INTRODUCTION: Some Muslim religious councils in Indonesia have ruled that measles vaccines contain haram (i.e., forbidden materials). This study evaluates the changes in measles vaccination coverage between 1991 and 2017 and compares vaccination coverage between Muslims and non-Muslims in Indonesia. METHODS: A total of 7 cross-sectional in-person surveys of mothers in 1991-2017 in Indonesia were analyzed in 2019. Participants were asked about religion in 1991-2007, and 100 data sets of religion were imputed for 2012 and 2017. In this multiple imputation analysis, binomial regression models output prevalence differences adjusted for wealth, education, child\u27s sex, and mother\u27s age. A quadratic term for year (year X year) and an interaction term between year and religion evaluated changes in vaccination over time by religion. RESULTS: The 7 data sets included 23,106 children aged 12-23 months, with the proportion of those who were Muslims ranging between 85% and 89% across the survey years. Between 1991 and 2017, measles vaccination coverage increased from 57% to 79% among non-Muslims and from 59% to 79% among Muslims. In the multivariable regression model, measles vaccination coverage increased by 1.6% each year (with a quadratic term of -0.05%, indicating some leveling over time). At baseline in 1991, non-Muslims had a vaccination coverage of 6.2% higher than that of Muslims, but this disparity decreased by -0.2% each year. CONCLUSIONS: Measles vaccination increased in both Muslims and non-Muslims in Indonesia but has stagnated in recent years. Because of increased attention among Muslim groups on haram materials in vaccines since 2017, future studies should continue to examine the relationship between religion and vaccine uptake in Indonesia. SUPPLEMENT INFORMATION: This article is part of a supplement entitled Global Vaccination Equity, which is sponsored by the Global Institute for Vaccine Equity at the University of Michigan School of Public Health

    The regulation of neutral amino acid transport by amino acid availability in animal cells

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    Animal cells regulate the activities of neutral amino acid transport Systems A and L to keep the intracellular supply of amino acids relatively constant. Transport System A activity increases dramatically in response to starvation of all the amino acids. Transport System L activity increases in response to starvation of a single substrate such as leucine. The mechanism of regulation appears to be different for Systems A and L.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25123/1/0000556.pd

    Significance of Keratinized Mucosa in Maintenance of Dental Implants With Different Surfaces

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142329/1/jper1410.pd

    The regulation of neutral amino acid transport in mammalian cells

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25214/1/0000654.pd
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