Fourier domain preconditioned conjugate gradient algorithm for atmospheric tomography

By 'atmospheric tomography' we mean the estimation of a layered atmospheric turbulence profile from measurements of the pupil-plane phase (or phase gradients) corresponding to several different guide star directions. We introduce what we believe to be a new Fourier domain preconditioned conjugate gradient (FD-PCG) algorithm for atmospheric tomography, and we compare its performance against an existing multigrid preconditioned conjugate gradient (MG-PCG) approach. Numerical results indicate that on conventional serial computers, FD-PCG is as accurate and robust as MG-PCG, but it is from one to two orders of magnitude faster for atmospheric tomography on 30 m class telescopes. Simulations are carried out for both natural guide stars and for a combination of finite-altitude laser guide stars and natural guide stars to resolve tip-tilt uncertainty

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair.

E-cadherin is a cell adhesion molecule best known for its function in suppressing tumor progression and metastasis. Here we show that E-cadherin promotes nucleotide excision repair through positively regulating the expression of xeroderma pigmentosum complementation group C (XPC) and DNA damage-binding protein 1 (DDB1). Loss of E-cadherin activates the E2F4 and p130/107 transcription repressor complexes to suppress the transcription of both XPC and DDB1 through activating the transforming growth factor-β (TGF-β) pathway. Adding XPC or DDB1, or inhibiting the TGF-β pathway, increases the repair of ultraviolet (UV)-induced DNA damage in E-cadherin-inhibited cells. In the mouse skin and skin tumors, UVB radiation downregulates E-cadherin. In sun-associated premalignant and malignant skin neoplasia, E-cadherin is downregulated in association with reduced XPC and DDB1 levels. These findings demonstrate a crucial role of E-cadherin in efficient DNA repair of UV-induced DNA damage, identify a new link between epithelial adhesion and DNA repair and suggest a mechanistic link of early E-cadherin loss in tumor initiation

Phase-reference VLBI Observations of the Compact Steep-Spectrum Source 3C 138

We investigate a phase-reference VLBI observation that was conducted at 15.4 GHz by fast switching VLBA antennas between the compact steep-spectrum radio source 3C 138 and the quasar PKS 0528+134 which are about 4$^\circ$ away on the sky. By comparing the phase-reference mapping with the conventional hybrid mapping, we demonstrate the feasibility of high precision astrometric measurements for sources separated by 4$^\circ$. VLBI phase-reference mapping preserves the relative phase information, and thus provides an accurate relative position between 3C 138 and PKS 0528+134 of $\Delta\alpha=-9^m46^s.531000\pm0^s.000003$ and $\Delta\delta=3^\circ6^\prime26^{\prime\prime}.90311\pm0^{\prime\prime}.00007$ (J2000.0) in right ascension and declination, respectively. This gives an improved position of the nucleus (component A) of 3C 138 in J2000.0 to be RA=$05^h 21^m 9^s.885748$ and Dec=$16^\circ 38' 22''.05261$ under the assumption that the position of calibrator PKS 0528+134 is correct. We further made a hybrid map by performing several iterations of CLEAN and self-calibration on the phase-referenced data with the phase-reference map as an input model for the first phase self-calibration. Compared with the hybrid map from the limited visibility data directly obtained from fringe fitting 3C 138 data, this map has a similar dynamic range, but a higher angular resolution. Therefore, phase-reference technique is not only a means of phase connection, but also a means of increasing phase coherence time allowing self-calibration technique to be applied to much weaker sources.Comment: 9 pages plus 2 figures, accepted by PASJ (Vol.58 No.6

Improvement of modal scaling factors using mass additive technique

A general investigation into the improvement of modal scaling factors of an experimental modal model using additive technique is discussed. Data base required by the proposed method consists of an experimental modal model (a set of complex eigenvalues and eigenvectors) of the original structure and a corresponding set of complex eigenvalues of the mass-added structure. Three analytical methods,i.e., first order and second order perturbation methods, and local eigenvalue modification technique, are proposed to predict the improved modal scaling factors. Difficulties encountered in scaling closely spaced modes are discussed. Methods to compute the necessary rotational modal vectors at the mass additive points are also proposed to increase the accuracy of the analytical prediction

Computing the ground state solution of Bose-Einstein condensates by a normalized gradient flow

In this paper, we prove the energy diminishing of a normalized gradient flow which provides a mathematical justification of the imaginary time method used in physical literatures to compute the ground state solution of Bose-Einstein condensates (BEC). We also investigate the energy diminishing property for the discretization of the normalized gradient flow. Two numerical methods are proposed for such discretizations: one is the backward Euler centered finite difference (BEFD), the other one is an explicit time-splitting sine-spectral (TSSP) method. Energy diminishing for BEFD and TSSP for linear case, and monotonicity for BEFD for both linear and nonlinear cases are proven. Comparison between the two methods and existing methods, e.g. Crank-Nicolson finite difference (CNFD) or forward Euler finite difference (FEFD), shows that BEFD and TSSP are much better in terms of preserving energy diminishing property of the normalized gradient flow. Numerical results in 1d, 2d and 3d with magnetic trap confinement potential, as well as a potential of a stirrer corresponding to a far-blue detuned Gaussian laser beam are reported to demonstrate the effectiveness of BEFD and TSSP methods. Furthermore we observe that the normalized gradient flow can also be applied directly to compute the first excited state solution in BEC when the initial data is chosen as an odd function.Comment: 28 pages, 6 figure

A new method to real-normalize measured complex modes

A time domain subspace iteration technique is presented to compute a set of normal modes from the measured complex modes. By using the proposed method, a large number of physical coordinates are reduced to a smaller number of model or principal coordinates. Subspace free decay time responses are computed using properly scaled complex modal vectors. Companion matrix for the general case of nonproportional damping is then derived in the selected vector subspace. Subspace normal modes are obtained through eigenvalue solution of the (M sub N) sup -1 (K sub N) matrix and transformed back to the physical coordinates to get a set of normal modes. A numerical example is presented to demonstrate the outlined theory