203 research outputs found
Experimental demonstration of the stability of Berry's phase for a spin-1/2 particle
The geometric phase has been proposed as a candidate for noise resilient
coherent manipulation of fragile quantum systems. Since it is determined only
by the path of the quantum state, the presence of noise fluctuations affects
the geometric phase in a different way than the dynamical phase. We have
experimentally tested the robustness of Berry's geometric phase for spin-1/2
particles in a cyclically varying magnetic field. Using trapped polarized
ultra-cold neutrons it is demonstrated that the geometric phase contributions
to dephasing due to adiabatic field fluctuations vanish for long evolution
times.Comment: 4 pages, 4 figure
Effective one-dimensionality of AC hopping conduction in the extreme disorder limit
It is argued that in the limit of extreme disorder AC hopping is dominated by
"percolation paths". Modelling a percolation path as a one-dimensional path
with a sharp jump rate cut-off leads to an expression for the universal AC
conductivity, that fits computer simulations in two and three dimensions better
than the effective medium approximation.Comment: 6 postscript figure
An Improved Neutron Electric Dipole Moment Experiment
A new measurement of the neutron EDM, using Ramsey's method of separated
oscillatory fields, is in preparation at the new high intensity source of
ultra-cold neutrons (UCN) at the Paul Scherrer Institute, Villigen, Switzerland
(PSI). The existence of a non-zero nEDM would violate both parity and time
reversal symmetry and, given the CPT theorem, might lead to a discovery of new
CP violating mechanisms. Already the current upper limit for the nEDM
(|d_n|<2.9E-26 e.cm) constrains some extensions of the Standard Model.
The new experiment aims at a two orders of magnitude reduction of the
experimental uncertainty, to be achieved mainly by (1) the higher UCN flux
provided by the new PSI source, (2) better magnetic field control with improved
magnetometry and (3) a double chamber configuration with opposite electric
field directions.
The first stage of the experiment will use an upgrade of the RAL/Sussex/ILL
group's apparatus (which has produced the current best result) moved from
Institut Laue-Langevin to PSI. The final accuracy will be achieved in a further
step with a new spectrometer, presently in the design phase.Comment: Flavor Physics & CP Violation Conference, Taipei, 200
Cubic boron nitride: a new prospective material for ultracold neutron application
For the first time, the neutron optical wall-potential of natural cubic boron
nitride (cBN) was measured at the ultracold neutron (UCN) source of the
research reactor TRIGA Mainz using the time-of-flight method (TOF). The samples
investigated had a wall-potential of (305 +/- 15) neV. This value is in good
agreement with the result extracted from neutron reflectometry data and
theoretical expectations. Because of its high critical velocity for UCN and its
good dielectric characteristics, cubic boron nitride coatings (isotopically
enriched) will be useful for a number of applications in UCN experiments
Measurement of the permanent electric dipole moment of the neutron
We present the result of an experiment to measure the electric dipole moment EDM) of the neutron at the Paul Scherrer Institute using Ramsey's method of separated oscillating magnetic fields with ultracold neutrons (UCN). Our measurement stands in the long history of EDM experiments probing physics violating time reversal invariance. The salient features of this experiment
were the use of a Hg-199 co-magnetometer and an array of optically pumped cesium vapor magnetometers to cancel and correct for magnetic field changes. The statistical analysis was performed on blinded datasets by two separate groups while the estimation of systematic effects profited from an
unprecedented knowledge of the magnetic field. The measured value of the neutron EDM is d_{\rm n} = (0.0\pm1.1_{\rm stat}\pm0.2_{\rmsys})\times10^{-26}e\,{\rm cm}
Helicobacter pylori infection and circulating ghrelin levels - A systematic review
BACKGROUND: The nature of the association between ghrelin, an orexigenic hormone produced mainly in the stomach, and Helicobacter pylori (H pylori), a bacterium that colonises the stomach, is still controversial. We examined available evidence to determine whether an association exists between the two; and if one exists, in what direction. METHODS: We reviewed original English language studies on humans reporting circulating ghrelin levels in H pylori infected and un-infected participants; and circulating ghrelin levels before and after H pylori eradication. Meta-analyses were conducted for eligible studies by combining study specific estimates using the inverse variance method with weighted average for continuous outcomes in a random effects model. RESULTS: Seventeen out of 27 papers that reported ghrelin levels in H pylori positive and negative subjects found lower circulating ghrelin levels in H pylori positive subjects; while 10 found no difference. A meta-analysis of 19 studies with a total of 1801 participants showed a significantly higher circulating ghrelin concentration in H pylori negative participants than in H pylori positive participants (Effect estimate (95%CI) = -0.48 (-0.60, -0.36)). However, eradicating H pylori did not have any significant effect on circulating ghrelin levels (Effect estimate (95% CI) = 0.08 (-0.33, 0.16); Test for overall effect: Z = 0.67 (P = 0.5)). CONCLUSIONS: We conclude that circulating ghrelin levels are lower in H pylori infected people compared to those not infected; but the relationship between circulating ghrelin and eradication of H pylori is more complex
Zinc Overload Enhances APP Cleavage and Aβ Deposition in the Alzheimer Mouse Brain
BACKGROUND: Abnormal zinc homeostasis is involved in β-amyloid (Aβ) plaque formation and, therefore, the zinc load is a contributing factor in Alzheimer's disease (AD). However, the involvement of zinc in amyloid precursor protein (APP) processing and Aβ deposition has not been well established in AD animal models in vivo. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, APP and presenilin 1 (PS1) double transgenic mice were treated with a high dose of zinc (20 mg/ml ZnSO4 in drinking water). This zinc treatment increased APP expression, enhanced amyloidogenic APP cleavage and Aβ deposition, and impaired spatial learning and memory in the transgenic mice. We further examined the effects of zinc overload on APP processing in SHSY-5Y cells overexpressing human APPsw. The zinc enhancement of APP expression and cleavage was further confirmed in vitro. CONCLUSIONS/SIGNIFICANCE: The present data indicate that excess zinc exposure could be a risk factor for AD pathological processes, and alteration of zinc homeostasis is a potential strategy for the prevention and treatment of AD
Plasticity and rectangularity in survival curves
Living systems inevitably undergo a progressive deterioration of physiological function with age and an increase of vulnerability to disease and death. To maintain health and survival, living systems should optimize survival strategies with adaptive interactions among molecules, cells, organs, individuals, and environments, which arises plasticity in survival curves of living systems. In general, survival dynamics in a population is mathematically depicted by a survival rate, which monotonically changes from 1 to 0 with age. It would be then useful to find an adequate function to describe complicated survival dynamics. Here we describe a flexible survival function, derived from the stretched exponential function by adopting an age-dependent shaping exponent. We note that the exponent is associated with the fractal-like scaling in cumulative mortality rate. The survival function well depicts general features in survival curves; healthy populations exhibit plasticity and evolve towards rectangular-like survival curves, as examples in humans or laboratory animals
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