Implementation of Regulation of the Director General of Islamic Bimas Number 379/2018 concerning Marriage Guidance as an Effort to Create the Sakinah Family

This study discusses aboutimplementation of the regulation of the Director General of Islamic Community Guidance No. 379/2018 regarding marriage guidance as an effort to create a sakinah family.. This study aims to determineimplementation of the regulation of the Director General of Islamic Community Guidance No. 373/2017 regarding marriage guidance as an effort to create a sakinah family.Types of researchisdescriptive qualitative. Descriptive research, location inWatangpulu District, Sidrap Regency mthrough observation, interviews, and documentation studies. Sources of data are the Head of KUA, Penghulu and religious instructors as well as prospective brides.The results of this study indicate that 1) household dynamics in forming a sakinah family in Watangpulu District, Sidrap Regency, family dynamics if not handled seriously will lead to divorce, so that is the basis for the link between marriage and divorce; 2) Supporting factors a) For participants who follow marriage guidance are very enthusiastic. b) Guidance material that is easy to understand, and 3) Implementation of the regulation of the Director General of Islamic Community Guidance No. 379/2018regarding marriage guidance for prospective brides in its implementation is quite effective

A first-principles study of helium storage in oxides and at oxide--iron interfaces

Density-functional theory calculations based on conventional as well as hybrid exchange-correlation functionals have been carried out to study the properties of helium in various oxides (Al2O3, TiO2, Y2O3, YAP, YAG, YAM, MgO, CaO, BaO, SrO) as well as at oxide-iron interfaces. Helium interstitials in bulk oxides are shown to be energetically more favorable than substitutional helium, yet helium binds to existing vacancies. The solubility of He in oxides is systematically higher than in iron and scales with the free volume at the interstitial site nearly independently of the chemical composition of the oxide. In most oxides He migration is significantly slower and He--He binding is much weaker than in iron. To quantify the solubility of helium at oxide-iron interfaces two prototypical systems are considered (Fe|MgO, Fe|FeO|MgO). In both cases the He solubility is markedly enhanced in the interface compared to either of the bulk phases. The results of the calculations allow to construct a schematic energy landscape for He interstitials in iron. The implications of these results are discussed in the context of helium sequestration in oxide dispersion strengthened steels, including the effects of interfaces and lattice strain.Comment: 13 pages, 10 figures, 4 table

Multilevel Analysis of Trachomatous Trichiasis and Corneal Opacity in Nigeria : The Role of Environmental and Climatic Risk Factors on the Distribution of Disease.

Funding: Jennifer L Smith was supported by the International Trachoma Initiative through a grant from the Bill and Melinda Gates Foundation. Anthony Solomon is a Wellcome Trust Intermediate Clinical Fellow (098521). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Dynamic Control of Dendritic mRNA Expression by CNOT7 Regulates Synaptic Efficacy and Higher Cognitive Function

Translation of mRNAs in dendrites mediates synaptic plasticity, the probable cellular basis of learning and memory. Coordination of translational inhibitory and stimulatory mechanisms, as well as dendritic transport of mRNA, is necessary to ensure proper control of this local translation. Here, we find that the deadenylase CNOT7 dynamically regulates dendritic mRNA translation and transport, as well as synaptic plasticity and higher cognitive function. In cultured hippocampal neurons, synaptic stimulation induces a rapid decrease in CNOT7, which, in the short-term, results in poly(A) tail lengthening of target mRNAs. However, at later times following stimulation, decreased poly(A) and dendritic localization of mRNA take place, similar to what is observed when CNOT7 is depleted over several days. In mice, CNOT7 is essential for hippocampal-dependent learning and memory. This study identifies CNOT7 as an important regulator of RNA transport and translation in dendrites, as well as higher cognitive function

Solution of hyperbolic bioheat transfer problems by numerical green's functions: the ExGA-linear θ method

This paper presents a time-domain formulation called Explicit Green's approach (ExGA) linear θ method for the solution of the bioheat equation. Starting from the hyperbolic bioheat equation, which includes the parabolic one as a special case, the linear method is incorporated into the standard ExGA time marching scheme. The numerical Green's function is firstly computed in the Laplace transform domain and then back-transformed to the time domain through the Stehfest inversion algorithm. The proposed formulation has the properties of stabilizing the results and suppressing numerical oscillations that appear in the presence of discontinuous solutions as assessed through the analysis of some bioheat transfer problems.