397 research outputs found
Atomic effects in astrophysical nuclear reactions
Two models are presented for the description of the electron screening
effects that appear in laboratory nuclear reactions at astrophysical energies.
The two-electron screening energy of the first model agrees very well with the
recent LUNA experimental result for the break-up reaction , which so far defies all available theoretical models.
Moreover, multi-electron effects that enhance laboratory reactions of the CNO
cycle and other advanced nuclear burning stages, are also studied by means of
the Thomas-Fermi model, deriving analytical formulae that establish a lower and
upper limit for the associated screening energy. The results of the second
model, which show a very satisfactory compatibility with the adiabatic
approximation ones, are expected to be particularly useful in future
experiments for a more accurate determination of the CNO astrophysical factors.Comment: 14 RevTex pages + 2 ps (revised) figures. Phys.Rev.C (in production
Screened thermonuclear reactions and predictive stellar evolution of detached double-lined eclipsing binaries
The low energy fusion cross sections of charged-particle nuclear reactions
(and the respective reaction rates) in stellar plasmas are enhanced due to
plasma screening effects. We study the impact of those effects on predictive
stellar evolution simulations for detached double-lined eclipsing binaries. We
follow the evolution of binary systems (pre-main sequence or main sequence
stars) with precisely determined radii and masses from 1.1Mo to 23Mo (from
their birth until their present state). The results indicate that all the
discrepancies between the screened and unscreened models (in terms of
luminosity, stellar radius, and effective temperature) are within the
observational uncertainties. Moreover, no nucleosynthetic or compositional
variation was found due to screening corrections. Therefore all thermonuclear
screening effects on the charged-particle nuclear reactions that occur in the
binary stars considered in this work (from their birth until their present
state) can be totally disregarded. In other words, all relevant
charged-particle nuclear reactions can be safely assumed to take place in a
vacuum, thus simplifying and accelerating the simulation processes.Comment: 5 RevTex pages,no figures. Accepted for publication in Phys.Rev.
Ethics roundtable debate: Withdrawal of tube feeding in a patient with persistent vegetative state where the patients wishes are unclear and there is family dissension
The decision to withdraw or withhold life supporting treatment in moribund patients is difficult under any circumstances. When the patient becomes incompetent to clarify their wishes regarding continued maintenance in long-term facilities, surrogates sometimes cannot agree, further clouding the issue. We examine a case where the State's interests come into play, forcing a controversial resolution
Rigorous and Approximated Solutions of the Consolidation Problem for a Soil Layer with Finite Thickness Under Cyclic Mechanical Loading
Amantadine variant - aryl conjugates that inhibit multiple M2 mutant - amantadine resistant influenza a viruses
Influenza A viruses can cause a serious future threat due to frequent mutations. Amantadine and rimantadine inhibit influenza A M2 wild-type (WT) viruses by binding and blocking M2 WT channel-mediated proton current. The resistant to the drugs amantadine and rimantadine influenza A viruses bearing the S31 N mutant in the M2 proton channel can be inhibited by amantadine - aryl conjugates, in which amantadine and an aryl group are linked through a methylene, which block M2 S31 N channel-mediated proton current. However, the M2 amantadine/rimantadine resistant viruses bearing one of the four mutations L26F, V27A, A30T, G34E in residues that line the M2 protein pore pose an additional concern for public health. Here, we designed 33 compounds based on the structure of three previously published and potent amantadine-aryl conjugates against M2 S31 N virus, by replacing amantadine with 16 amantadine variants. The compounds were tested against M2 WT and the five M2 amantadine-resistant viruses aiming at identifying inhibitors against multiple M2 mutant - amantadine resistant viruses. We identified 16 compounds that inhibited in vitro two influenza A viruses with M2 WT or L26F channels. Additionally, compounds 21 or 32 or 33, which are conjugates of the rimantadine variant with CMe2 (instead of CHMe in rimantadine) or the diamantylamine or the 4-(1-adamantyl)benzenamine with the 2-hydroxy-4-methoxyphenyl aryl group, were in vitro inhibitors against three influenza A viruses with M2 WT or L26F or S31 N, while compound 21 inhibited also in vitro the M2 G34E virus and 32 inhibited also in vitro the M2 A30T virus. For these compounds we performed a preliminary drug metabolism and pharmacokinetics study. Also, using electrophysiology, we showed that compound 21 was an efficient blocker of the M2 WT and M2 L26F channels, compound 32 blocked efficiently the M2 WT channel and compound 33 blocked the M2 WT, L26F and V27A channels. The drug metabolism and pharmacokinetics studies showed these compounds need further optimization
Prospects for the CERN Axion Solar Telescope Sensitivity to 14.4 keV Axions
The CERN Axion Solar Telescope (CAST) is searching for solar axions using the
9.0 T strong and 9.26 m long transverse magnetic field of a twin aperture LHC
test magnet, where axions could be converted into X-rays via reverse Primakoff
process. Here we explore the potential of CAST to search for 14.4 keV axions
that could be emitted from the Sun in M1 nuclear transition between the first,
thermally excited state, and the ground state of 57Fe nuclide. Calculations of
the expected signals, with respect to the axion-photon coupling, axion-nucleon
coupling and axion mass, are presented in comparison with the experimental
sensitivity.Comment: 4 pages, 1 figure. Submitted to Nucl. Instr. and Meth.
CAST constraints on the axion-electron coupling
In non-hadronic axion models, which have a tree-level axion-electron
interaction, the Sun produces a strong axion flux by bremsstrahlung, Compton
scattering, and axio-recombination, the "BCA processes." Based on a new
calculation of this flux, including for the first time axio-recombination, we
derive limits on the axion-electron Yukawa coupling g_ae and axion-photon
interaction strength g_ag using the CAST phase-I data (vacuum phase). For m_a <
10 meV/c2 we find g_ag x g_ae< 8.1 x 10^-23 GeV^-1 at 95% CL. We stress that a
next-generation axion helioscope such as the proposed IAXO could push this
sensitivity into a range beyond stellar energy-loss limits and test the
hypothesis that white-dwarf cooling is dominated by axion emission
First results from the CERN Axion Solar Telescope (CAST)
Hypothetical axion-like particles with a two-photon interaction would be
produced in the Sun by the Primakoff process. In a laboratory magnetic field
(``axion helioscope'') they would be transformed into X-rays with energies of a
few keV. Using a decommissioned LHC test magnet, CAST has been running for
about 6 months during 2003. The first results from the analysis of these data
are presented here. No signal above background was observed, implying an upper
limit to the axion-photon coupling < 1.16 10^{-10} GeV^-1 at 95% CL for m_a
<~0.02 eV. This limit is comparable to the limit from stellar energy-loss
arguments and considerably more restrictive than any previous experiment in
this axion mass range.Comment: 4 pages, accepted by PRL. Final version after the referees comment
Search for solar axion emission from 7Li and D(p,gamma)3He nuclear decays with the CAST gamma-ray calorimeter
We present the results of a search for a high-energy axion emission signal
from 7Li (0.478 MeV) and D(p,gamma)3He (5.5 MeV) nuclear transitions using a
low-background gamma-ray calorimeter during Phase I of the CAST experiment.
These so-called "hadronic axions" could provide a solution to the long-standing
strong-CP problem and can be emitted from the solar core from nuclear M1
transitions. This is the first such search for high-energy pseudoscalar bosons
with couplings to nucleons conducted using a helioscope approach. No excess
signal above background was found.Comment: 20 pages, 8 figures, final version to be published in JCA
Solar axion search with the CAST experiment
The CAST (CERN Axion Solar Telescope) experiment is searching for solar
axions by their conversion into photons inside the magnet pipe of an LHC
dipole. The analysis of the data recorded during the first phase of the
experiment with vacuum in the magnet pipes has resulted in the most restrictive
experimental limit on the coupling constant of axions to photons. In the second
phase, CAST is operating with a buffer gas inside the magnet pipes in order to
extent the sensitivity of the experiment to higher axion masses. We will
present the first results on the data taking as well as the
system upgrades that have been operated in the last year in order to adapt the
experiment for the data taking. Expected sensitivities on the
coupling constant of axions to photons will be given for the recent run just started in March 2008.Comment: Proceedings of the ICHEP 2008 conferenc
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