Detection of X-ray periodicity from a new eclipsing polar candidate XGPS-I J183251-100106

We report the results from a detailed analysis of an archival XMM-Newton observation of the X-ray source XGPS-I J183251-100106, which has been suggested as a promising magnetic cataclysmic variable candidate based on its optical properties. A single periodic signal of 1.5 hrs is detected from all EPIC cameras on board XMM-Newton. The phase-averaged X-ray spectrum can be well-modeled with a thermal bremsstrahlung of a temperature kT~50 keV. Both X-ray spectral and temporal behavior of this system suggest it as a eclipsing cataclysmic variable of AM Herculis (or polar) type.Comment: 15 pages, 6 figures, accepted for publication in Ap

Discovery of X-ray pulsations from "next Geminga" - PSR J1836+5925

We report the X-ray pulsation of ~173.3 ms for the "next Geminga", PSR J1836+5925, with recent XMM-Newton investigations. The X-ray periodicity is consistent wtih the gamma-ray ephemeris at the same epoch. The X-ray folded light curve has a sinusoidal structure which is different from the double-peaked gamma-ray pulse profile. We have also analysed the X-ray phase-averaged spectra which shows the X-ray emission from PSR J1836+5925 is thermal dominant. This suggests the X-ray pulsation mainly originates from the modulated hot spot on the stellar surface.Comment: 7 pages, 3 figures, 1 table, accepted for publication in ApJ Lette

A study of resiliency among Chinese health care workers: Capacity to cope with workplace stress

This paper reports a study of resiliency to cope with workplace stress among Chinese health care workers. We adopted a qualitative-quantitative-biomarker approach to conduct interviews, focus group discussions, and a two-wave longitudinal survey. Wave 1 survey was conducted among health care workers in Hong Kong and Mainland China (N = 773). Amongst them, 287 took part in Wave 2 survey. A confirmatory factor analysis consistently supported a 9-item scale. A sub-sample's (N = 33) resiliency was positively related to salivary IgA levels (an immune marker). Results from hierarchical regressions demonstrated that resiliency measured in Wave 1 was positively related to job satisfaction, work-life balance, and quality of life; and negatively related to physical/psychological symptoms and injuries at work in Wave 2. © 2009 Elsevier Inc. All rights reserved.postprin

A Tourism Financial Conditions Index

__Abstract__ The paper uses monthly data on financial stock index returns, tourism stock sub-index returns, effective exchange rate returns and interest rate differences from April 2005 – August 2013 for Taiwan that applies Chang’s (2014) novel approach for constructing a tourism financial indicator, namely the Tourism Financial Conditions Index (TFCI). The TFCI is an adaptation and extension of the widely-used Monetary Conditions Index (MCI) and Financial Conditions Index (FCI) to tourism stock data. However, the method of calculation of the TFCI is different from existing methods of constructing the MCI and FCI in that the weights are estimated empirically. The empirical findings show that TFCI is estimated quite accurately using the estimated conditional mean of the tourism stock index returns. The new TFCI is straightforward to use and interpret, and provides interesting insights in predicting the current economic and financial environment for tourism stock index returns that are based on publicly available information. In particular, the use of market returns on the tourism stock index as the sole indicator of the tourism sector, as compared with the general activity of economic variables on tourism stocks, is shown to provide an exaggerated and excessively volatile explanation of tourism financial conditions

GPER-induced signaling is essential for the survival of breast cancer stem cells.

G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells. However, its role in breast cancer stem cells (BCSCs) remains unclear. Here we showed greater expression of GPER in BCSCs than non-BCSCs of three patient-derived xenografts of ER- /PR+ breast cancers. GPER silencing reduced stemness features of BCSCs as reflected by reduced mammosphere forming capacity in vitro, and tumor growth in vivo with decreased BCSC populations. Comparative phosphoproteomics revealed greater GPER-mediated PKA/BAD signaling in BCSCs. Activation of GPER by its ligands, including tamoxifen (TMX), induced phosphorylation of PKA and BAD-Ser118 to sustain BCSC characteristics. Transfection with a dominant-negative mutant BAD (Ser118Ala) led to reduced cell survival. Taken together, GPER and its downstream signaling play a key role in maintaining the stemness of BCSCs, suggesting that GPER is a potential therapeutic target for eradicating BCSCs

The FENE dumbbell polymer model: existence and uniqueness of solutions for the momentum balance equation

We consider the FENE dumbbell polymer model which is the coupling of the incompressible Navier-Stokes equations with the corresponding Fokker-Planck-Smoluchowski di ffusion equation. We show global well-posedness in the case of a 2D bounded domain. We assume in the general case that the initial velocity is sufficiently small and the initial probability density is sufficiently close to the equilibrium solution; moreover an additional condition on the coeffcients is imposed. In the corotational case, we only assume that the initial probability density is sufficiently close to the equilibrium solution