66,050 research outputs found

    Why practical theology must go public

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    This is the author's post-print pdf version of an article published in Practical Theology. The article can be found at http://essential.metapress.com/content/122841/This journal article makes the case for a strong affinity between pastoral studies and practical theology as conceived in the UK and the emerging field of public theology

    Health, wealth or wisdom? Religion and the paradox of prosperity

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    This is the author's pdf version of an article published in International Journal of Public Theology 2009. The published version of the article is available at https://www.brill.nl/international-journal-public-theologyThis article discusses the role of religious values and participation in the 'happiness hypothesis'

    Manifestations of the post-secular emerging within discourses of posthumanism

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    This paper discusses the concepts of posthuman and post-secular in critical theory

    Method and apparatus for telemetry adaptive bandwidth compression

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    Methods and apparatus are provided for automatic and/or manual adaptive bandwidth compression of telemetry. An adaptive sampler samples a video signal from a scanning sensor and generates a sequence of sampled fields. Each field and range rate information from the sensor are hence sequentially transmitted to and stored in a multiple and adaptive field storage means. The field storage means then, in response to an automatic or manual control signal, transfers the stored sampled field signals to a video monitor in a form for sequential or simultaneous display of a desired number of stored signal fields. The sampling ratio of the adaptive sample, the relative proportion of available communication bandwidth allocated respectively to transmitted data and video information, and the number of fields simultaneously displayed are manually or automatically selectively adjustable in functional relationship to each other and detected range rate. In one embodiment, when relatively little or no scene motion is detected, the control signal maximizes sampling ratio and causes simultaneous display of all stored fields, thus maximizing resolution and bandwidth available for data transmission. When increased scene motion is detected, the control signal is adjusted accordingly to cause display of fewer fields. If greater resolution is desired, the control signal is adjusted to increase the sampling ratio

    Finding ourselves: Theology, place, and human flourishing

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    This is the author's PDF version of the book chapter.This book chapter is about being "lost" and "found" and of the significance of space and place for "finding ourselves" as fully human. Tim Gorringe's work on culture and the built environment will inform some of the author's reflection on this

    Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs

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    Oncolytic viruses are emerging as a potential new way of treating cancers. They are selectively replication-competent viruses that propagate only in actively dividing tumor cells but not in normal cells and, as a result, destroy the tumor cells by consequence of lytic infection. At least six different oncolytic herpes simplex viruses (oHSVs) have undergone clinical trials worldwide to date, and they have demonstrated an excellent safety profile and intimations of efficacy. The first pivotal Phase III trial with an oHSV, talimogene laherparepvec (T-Vec [OncoVex<sup>GM-CSF</sup>]), is almost complete, with extremely positive early results reported. Intuitively, therapeutically beneficial interactions between oHSV and chemotherapeutic and targeted therapeutic drugs would be limited as the virus requires actively dividing cells for maximum replication efficiency and most anticancer agents are cytotoxic or cytostatic. However, combinations of such agents display a range of responses, with antagonistic, additive, or, perhaps most surprisingly, synergistic enhancement of antitumor activity. When synergistic interactions in cancer cell killing are observed, chemotherapy dose reductions that achieve the same overall efficacy may be possible, resulting in a valuable reduction of adverse side effects. Therefore, the combination of an oHSV with “standard-of-care” drugs makes a logical and reasonable approach to improved therapy, and the addition of a targeted oncolytic therapy with “standard-of-care” drugs merits further investigation, both preclinically and in the clinic. Numerous publications report such studies of oncolytic HSV in combination with other drugs, and we review their findings here. Viral interactions with cellular hosts are complex and frequently involve intracellular signaling networks, thus creating diverse opportunities for synergistic or additive combinations with many anticancer drugs. We discuss potential mechanisms that may lead to synergistic interactions

    Simplified system displays complex curves corresponding to input data

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    Cathode ray oscilloscope displays curves or contours of complex shapes corresponding to sets of x,y coordinates. It requires few storage facilities and produces a rapid display of complex curves with a fewer number of commands than previous systems

    Modelling nominal debt contracts and fixed rate debt

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    We provide a simple model of sticky nominal debt contracts and fixed rate debt that can easily be embedded in a dynamic general equilibrium framework. Once linearized, the debt process increases the order of autoregressive dynamics in the system by one; thus potentially introducing more complex adjustment processes
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