545 research outputs found

    Pengaruh Gaya Kepemimpinan, Budaya Organisasi, dan Nilai-nilai Personal terhadap Kinerja Pegawai di Dinas Pendidikan Nasional Provinsi Sulawesi Utara

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    Sumber Daya Manusia (SDM) menjadi penting dalam keberhasilan suatu organisasi. Persaingan global saat ini membuat organisasi menyiapkan berbagai strategi pengembangan kemampuan sumber daya manusia agar dapat siap bersaing dengan organisasi lain. Keberlangsungan organisasi tidak hanya dipicu dari performa tenaga kerja saja melainkan gaya kepemimpinan yang dapat membangun motivasi kerja, budaya organisasi yang menciptakan Kenyamanan bagi pekerja. Selanjutnya nilai-nilai personal yang nantinya akan berpengaruh pada kinerja baik bagi seluruh pegawai dalam suatu organisasi. Faktor-faktor ini yang akan menjadi fokus telaah dalam penulisan ini, dengan mengambil objek teliti yaitu pegawai pada Dinas Pendidikan Nasional Provinsi Sulawesi Utara. Tujuan penelitian ini untuk menganalisa pengaruh Gaya Kepemimpinan, Budaya Organisasi, dan Nilai-Nilai Personal terhadap Kinerja Pegawai di Dinas Pendidikan Nasional Provinsi Sulawesi Utara. Metode penelitian yaitu kuantitatif dengan analisa data menggunakan regresi berganda. Hasil penelitian menunjukkan bahwa Gaya Kepemimpinan, Budaya Organisasi, dan Nilai-Nilai Personal memiliki pengaruh yang positif dan signifikan terhadap Kinerja Pegawai di Dinas Pendidikan Nasional Provinsi Sulawesi Utara. Sebaiknya pimpinan Kantor Dinas Pendidikan Nasional Provinsi Sulawesi Utara tetap mengarahkan serta mempengaruhi secara positif para pegawai, dan juga perlu untuk tetap mempertahankan serta meningkatkan budaya organisasi yang lebih baik sehingga dapat meningkatkan kinerja pegawai. Kata kunci: gaya kepemimpinan, budaya organisasi, nilai-nilai personal, kinerja pegawa

    Interaksi Trofik Jenis Serangga Di Atas Permukaan Tanah Dan Permukaan Tanah Beberapa Pertanaman Varietas Jagung (Zea Mays Linn.)

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    The aim of the reasearch was to know the tropic interaction of insect on the soil surface and above of soil surface for many varieties of corn (Zea mays Linn.) and index diversity value of insect of corn. The research was conducted in BBI of Tanjung Slamat and Agriculture Pest Laboratory in University of Sumatera Utara, Medan from November (2013) until March (2014). The insect trapped used yellow stiky trap and pitt fall trap. The result of the research showed that insects caught each consist of 9 ordo and 33 family. The highest relative density values in PRG NK603 (application of glyphosate) variety was 16.691% and the lowest was 0.681%. The highest relative density values in PRG NK603 variety was 16.363% and the lowest was 0.578%. The highest relative density values in C7 variety was 15.499 % and the lowest was 0.577 %. The highest relative density values in DK979 variety was 15.073 % and the lowest was 0.450 %. Shanon-Weiner (H') Index diversity value of insect in PRG NK603 (application of glyphosate) variety was 2.950309 (standart), in PRG NK603 was 3.006432 (stable), in C7 variety was 3.051692 (stable), and in DK979 variety was 3.082916 (stable)

    LNK (SH2B3): paradoxical effects in ovarian cancer.

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    LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it downregulates activated tyrosine kinases at the cell surface resulting in an antiproliferative effect. To date, no studies have examined activities of LNK in solid tumors. In this study, we found by in silico analysis and staining tissue arrays that the levels of LNK expression were elevated in high-grade ovarian cancer. To test the functional importance of this observation, LNK was either overexpressed or silenced in several ovarian cancer cell lines. Remarkably, overexpression of LNK rendered the cells resistant to death induced by either serum starvation or nutrient deprivation, and generated larger tumors using a murine xenograft model. In contrast, silencing of LNK decreased ovarian cancer cell growth in vitro and in vivo. Western blot studies indicated that overexpression of LNK upregulated and extended the transduction of the mitogenic signal, whereas silencing of LNK produced the opposite effects. Furthermore, forced expression of LNK reduced cell size, inhibited cell migration and markedly enhanced cell adhesion. Liquid chromatography-mass spectroscopy identified 14-3-3 as one of the LNK-binding partners. Our results suggest that in contrast to the findings in hematologic malignancies, the adaptor protein LNK acts as a positive signal transduction modulator in ovarian cancers

    Medical Care Costs of Breast Cancer in Privately Insured Women Aged 18–44 Years

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    Breast cancer in women aged 18–44 years accounts for approximately 27,000 newly diagnosed cases and 3,000 deaths annually. When tumors are diagnosed, they are usually aggressive, resulting in expensive treatment costs. The purpose of this study is to estimate the prevalent medical costs attributable to breast cancer treatment among privately insured younger women

    Estimation of Breast Cancer Incident Cases and Medical Care Costs Attributable to Alcohol Consumption Among Insured Women Aged <45 Years in the U.S.

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    This study estimated the percentage of breast cancer cases, total number of incident cases, and total annual medical care costs attributable to alcohol consumption among insured younger women (aged 18–44 years) by type of insurance and stage at diagnosis
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