Identifying changes in agricultural practices and policy interventions for sustainable intensification of farm systems in southern Mali

Achieving sustainable development goals for smallholder rural populations within the next eleven years is challenging: besides environmental and climate pressures, rising rural population and unfavorable institutional arrangements diminish the room to manoeuvre within the current system’s settings. New farming practices and progressive policies to trigger and support drastic changes are needed. A large array of innovative farming practices have been developed across sub-Saharan Africa (e.g. Snapp et al., 2010). Our objective was to grasp the scale of the challenge: what is the potential of changes in farm practices to improve farming sustainability in southern Mali, a region that is representative for land-scarce sub-Saharan Africa?Which policies are needed to support sustainable development

Multidimensional assessment of smallholder farming systems’ sustainability

A holistic systems-oriented approach is strongly recommended to address the intractable challenges of complex smallholder farm and food systems in different ecologies, and cultures. In the present study, we have developed and piloted a multidimensional framework for assessing farming systems sustainability and resilience (FSSR) which is easily measurable and comparable. It considers five major sustainability domains: environmental, economic, productivity, social and human well-being. Further each domain is divided into different themes, sub-themes and indicators. The indicators have been finalized with rounds of stakeholders’ consultations involving farmers, researchers, development actors besides literature. We identified 115 measurable indicators: environmental (34), economic (29), productivity (12), social (25) and human well-being (15) in the final framework which are aggregated into an index with a maximum value of 100 representing the level of sustainability and resilience at different scales. In our case study the overall sustainability index scores ranged between 42 to 47 across farm types. The overall and domain level sustainability scores varied widely across individual households and farm types. The present framework could be very useful tool for researchers, development actors and institutions to identify entry points to design context-specific strategies to improve sustainability and resilience of farming systems in vulnerable regions

Multidimensional framework for measuring sustainability and resilience of farming systems

Natural resources, are fundamental for the structure and function of agricultural systems and for social and environmental sustainability in support of life on earth. Historically, global agricultural development has been narrowly focused on increased productivity rather than on a more holistic integration of natural resource management with food and nutritional security. Now it is strongly suggested that a holistic, or systems-oriented approach, will be needed to address the intractable challenges associated with the complexity of food and other production systems in different ecologies, locations and cultures. In the present study we have developed and piloted a multidimensional framework for assessing farming systems sustainability and resilience (FSSR). The quantification framework is easily measurable and comparable across farm households, farming systems and beyond. It considers five major domains of the farming systems namely environmental, economic, productivity, social and human well-being. In the subsequent stages of measurement each domain is divided into different themes, then sub-themes and indicators. The indicators in our study have been finalized with rounds of stakeholders’ consultations involving farmers, researches, development experts besides literature. Finally, we identified a total of 115 indicators: environmental (34), economic (29), productivity (12), social (25) and human well-being (15) in the final framework which are measurable and would be able to provide an index value representing level of sustainability of farming systems at different scales: farm household, domain and farming system considering appropriate weights of different domains. The FSSR framework could be a very useful tool for designing the context specific strategies to address farm sustainability challenges

Economic trade-offs of biomass use in crop-livestock systems: Exploring more sustainable options in semi-arid Zimbabwe

In complex mixed crop-livestock systems with limited resources and biomass scarcity, crop residues play an important but increasingly contested role. This paper focuses on farming systems in the semi-arid areas of Zimbabwe, where biomass production is limited and farmers integrate crop and livestock activities. Conservation Agriculture (CA) is promoted to intensify crop production, emphasizing the retention of surface mulch with crop residues (CR). This paper quantifies the associated potential economic trade-offs and profitability of using residues for soil amendment or as livestock feed, and explores alternative biomass production options. We draw on household surveys, stakeholder feedback, crop, livestock and economic modeling tools. We use the Trade-Off Analysis Model for Multi Dimensional Impact Assessment (TOA-MD) to compare different CR use scenarios at community level and for different farm types: particularly the current base system (cattle grazing of maize residues) and sustainable intensification alternatives based on a CA option (mulching using maize residues ± inorganic fertilizer) and a maize–mucuna (Mucuna pruriens) rotation. Our results indicate that a maize–mucuna rotation can reduce trade-offs between CR uses for feed and mulch, providing locally available organic soil enhancement, supplementary feed and a potential source of income. Conservation Agriculture without fertilizer application and at non-subsidized fertilizer prices is not financially viable; whereas with subsidized fertilizer it can benefit half the farm population. The poverty effects of all considered alternative biomass options are however limited; they do not raise income sufficiently to lift farmers out of poverty. Further research is needed to establish the competitiveness of alternative biomass enhancing technologies and the socio-economic processes that can facilitate sustainable intensification of mixed crop-livestock systems, particularly in semi-arid environments

Crop–Livestock Intensification in the Face of Climate Change: Exploring Opportunities to Reduce Risk and Increase Resilience in Southern Africa by Using an Integrated Multi-modeling Approach

The climate of Southern Africa is highly variable at most time-scales and follows a pronounced gradient with arid conditions in the west and humid conditions in the east. There is also a marked latitudinal rainfall distribution pattern, with the southern part having a low rainfall index and high variability and the northern part having higher annual rainfall and lower interannual variability (Kandji et al., 2006). Over the last 100 years, temperatures have increased by about 0.5◦C in the region and downward trends in rainfall have also occurred (Kandji et al., 2006; Morton, 2007). There has also been an increase in drought eventswith over 15 drought events reported in the region between 1988 and 1992. The frequency and intensity of El Nin˜o episodes have increased. Prior to the 1980s, strong El Nin˜o events occurred every 10–20 years; between 1980 and 2000, the region experienced five episodes with the 1982–1983 and 1997–1998 episodes being the most intense of the century (Reason and Jagadheesha, 2005; Rouault and Richard, 2005). These episodes have contributed to stagnant or decreasing agricultural production and worsening food insecurity in the region (Kandji et al., 2006). Unfavorable climatic conditions and projected climate change are among the major obstacles to achieving food security in the region and also have dire consequences for macro-economic performance

Inference of Antibiotic Resistance and Virulence among Diverse Group A Streptococcus Strains Using emm Sequencing and Multilocus Genotyping Methods

typing (direct sequencing of the genomic segment coding for the antigenic portion of the M protein) or by multilocus genotyping methods. Phenotype analysis, including critical AbR typing, is generally achieved by much slower and more laborious direct culture-based methods. type and the associated AbR and virulence phenotypes. types

Motor Learning in Children with Neurofibromatosis Type I

The aim of this study was to quantify the frequently observed problems in motor control in Neurofibromatosis type 1 (NF1) using three tasks on motor performance and motor learning. A group of 70 children with NF1 was compared to age-matched controls. As expected, NF1 children showed substantial problems in visuo-motor integration (Beery VMI). Prism-induced hand movement adaptation seemed to be mildly affected. However, no significant impairments in the accuracy of simple eye or hand movements were observed. Also, saccadic eye movement adaptation, a cerebellum dependent task, appeared normal. These results suggest that the motor problems of children with NF1 in daily life are unlikely to originate solely from impairments in motor learning. Our findings, therefore, do not support a general dysfunction of the cerebellum in children with NF1

Prader–Willi syndrome and autism spectrum disorders: an evolving story

Prader–Willi syndrome (PWS) is well-known for its genetic and phenotypic complexities. Caused by a lack of paternally derived imprinted material on chromosome 15q11–q13, individuals with PWS have mild to moderate intellectual disabilities, repetitive and compulsive behaviors, skin picking, tantrums, irritability, hyperphagia, and increased risks of obesity. Many individuals also have co-occurring autism spectrum disorders (ASDs), psychosis, and mood disorders. Although the PWS 15q11–q13 region confers risks for autism, relatively few studies have assessed autism symptoms in PWS or directly compared social, behavioral, and cognitive functioning across groups with autism or PWS. This article identifies areas of phenotypic overlap and difference between PWS and ASD in core autism symptoms and in such comorbidities as psychiatric disorders, and dysregulated sleep and eating. Though future studies are needed, PWS provides a promising alternative lens into specific symptoms and comorbidities of autism

Streptococcal necrotising fasciitis from diverse strains of Streptococcus pyogenes in tropical northern Australia: case series and comparison with the literature

BACKGROUND: Since the mid-1980's there has been a worldwide resurgence of severe disease from group A streptococcus (GAS), with clonal clusters implicated in Europe and the United States. However GAS associated sepsis and rheumatic fever have always remained at high levels in many less developed countries. In this context we aimed to study GAS necrotising fasciitis (NF) in a region where there are high background rates of GAS carriage and disease. METHODS: We describe the epidemiology, clinical and laboratory features of 14 consecutive cases of GAS NF treated over a seven year period from tropical northern Australia. RESULTS: Incidence rates of GAS NF in the Aboriginal population were up to five times those previously published from other countries. Clinical features were similar to those described elsewhere, with 7/14 (50%) bacteremic and 9/14 (64%) having associated streptococcal toxic shock syndrome. 11/14 (79%) had underlying chronic illnesses, including all four fatalities (29% mortality overall). Important laboratory differences from other series were that leukocytosis was absent in 9/14 (64%) but all had substantial lymphopenia. Sequence typing of the 14 NF-associated GAS isolates showed no clonality, with only one emm type 1 and two emm type 3 strains. CONCLUSIONS: While NF clusters can occur from a single emergent GAS clone, this was not evident in our tropical region, where high rates of NF parallel high overall rates of GAS infection from a wide diversity of strains. The specific virulence factors of GAS strains which do cause NF and the basis of the inadequate host response in those patients who develop NF on infection with these GAS require further elucidation