2,118 research outputs found
Adaptive laser link reconfiguration using constraint propagation
This paper describes Harris AI research performed on the Adaptive Link Reconfiguration (ALR) study for Rome Lab, and focuses on the application of constraint propagation to the problem of link reconfiguration for the proposed space based Strategic Defense System (SDS) Brilliant Pebbles (BP) communications system. According to the concept of operations at the time of the study, laser communications will exist between BP's and to ground entry points. Long-term links typical of RF transmission will not exist. This study addressed an initial implementation of BP's based on the Global Protection Against Limited Strikes (GPALS) SDI mission. The number of satellites and rings studied was representative of this problem. An orbital dynamics program was used to generate line-of-site data for the modeled architecture. This was input into a discrete event simulation implemented in the Harris developed COnstraint Propagation Expert System (COPES) Shell, developed initially on the Rome Lab BM/C3 study. Using a model of the network and several heuristics, the COPES shell was used to develop the Heuristic Adaptive Link Ordering (HALO) Algorithm to rank and order potential laser links according to probability of communication. A reduced set of links based on this ranking would then be used by a routing algorithm to select the next hop. This paper includes an overview of Constraint Propagation as an Artificial Intelligence technique and its embodiment in the COPES shell. It describes the design and implementation of both the simulation of the GPALS BP network and the HALO algorithm in COPES. This is described using a 59 Data Flow Diagram, State Transition Diagrams, and Structured English PDL. It describes a laser communications model and the heuristics involved in rank-ordering the potential communication links. The generation of simulation data is described along with its interface via COPES to the Harris developed View Net graphical tool for visual analysis of communications networks. Conclusions are presented, including a graphical analysis of results depicting the ordered set of links versus the set of all possible links based on the computed Bit Error Rate (BER). Finally, future research is discussed which includes enhancements to the HALO algorithm, network simulation, and the addition of an intelligent routing algorithm for BP
Simulation studies of improved sounding systems
Two instrument designs for indirect satellite sounding of the atmosphere in the infrared are represented by the High Resolution Infra-Red Sounder, Model 2 (HIRS-2) and by the Advanced Meteorological Temperature Sounder (AMTS). The relative capabilities of the two instruments were tested by simulating satellite measurements from a group of temperature soundings, allowing the two participants to retrieve the temperature profiles from the simulated data, and comparing the results with the original temperature profiles. Four data sets were produced from radiosondes data extrapolated to a suitable altitude, representing continents and oceans, between 30S and 30N. From the information available, temperature profiles were retrieved by two different methods, statistical regression and inversion of the radiative transfer equation. Results show the consequence of greater spectral purity, concomitant increase in the number of spectral intervals, and the better spatial resolution in partly clouded areas. At the same time, the limitation of the HIRS-2 without its companion instrument leads to some results which should be ignored in comparing the two instruments. A clear superiority of AMTS results is shown
Morphology Effectively Controls Singlet-Triplet Exciton Relaxation and Charge Transport in Organic Semiconductors
We present a comparative study of ultrafast photo-conversion dynamics in
tetracene (Tc) and pentacene (Pc) single crystals and Pc films using optical
pump-probe spectroscopy. Photo-induced absorption in Tc and Pc crystals is
activated and temperature-independent respectively, demonstrating dominant
singlet-triplet exciton fission. In Pc films (as well as C-doped films)
this decay channel is suppressed by electron trapping. These results
demonstrate the central role of crystallinity and purity in photogeneration
processes and will constrain the design of future photovoltaic devices.Comment:
SNARE mimic peptide triggered membrane fusion kinetics revealed using single particle techniques
Membrane fusion is an essential part of the proper functioning of life. As such it is not only important that organisms carefully regulate the process, but also that it is well understood. One way to facilitate and study membrane fusion is to use artificial, minimalist, fusion peptides. In this study the efficiency and kinetics of two fusion peptides, denoted CPE and CPK, were studied using single-particle TIRF microscopy. CPE and CPK are helical peptides which interact with each other, forming a coiled-coil motif. The peptides can be inserted into a lipid membrane using a lipid anchor, and if these peptides are anchored in opposing lipid membranes, then the coiled-coil interaction can provide the mechanical force necessary to overcome the energy barrier to initiate fusion, much in the same way the SNARE complex does. In this study we find that the fusogenic facilitation of CPE and CPK in liposomes is, at least partially, dependent on the size of the particle. In addition, under certain fusogenic conditions such as when using small liposomes of ∼60 nm in diameter, CPK alone is enough to facilitate membrane fusion in both bulk and single-particle studies. We show this using bulk lipid mixing assays utilizing FRET and single-particle TIRF, making use of dequenching fluorophores to indicate fusion. This provides us with new insights into the mechanisms of peptide-mediated membrane fusion and illuminates both challenges as well as opportunities when designing drug delivery systems.</p
Uptake and Participation in Physical Activity Referral Schemes in the UK: An Investigation of Patients Referred with Mental Health Problems
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
The Oldest Stars of the Extremely Metal-Poor Local Group Dwarf Irregular Galaxy Leo A
We present deep Hubble Space Telescope single-star photometry of Leo A in B,
V, and I. Our new field of view is offset from the centrally located field
observed by Tolstoy et al. (1998) in order to expose the halo population of
this galaxy. We report the detection of metal-poor red horizontal branch stars,
which demonstrate that Leo A is not a young galaxy. In fact, Leo A is as least
as old as metal-poor Galactic Globular Clusters which exhibit red horizontal
branches, and are considered to have a minimum age of about 9 Gyr. We discuss
the distance to Leo A, and perform an extensive comparison of the data with
stellar isochrones. For a distance modulus of 24.5, the data are better than
50% complete down to absolute magnitudes of 2 or more. We can easily identify
stars with metallicities between 0.0001 and 0.0004, and ages between about 5
and 10 Gyr, in their post-main-sequence phases, but lack the detection of
main-sequence turnoffs which would provide unambiguous proof of ancient (>10
Gyr) stellar generations. Blue horizontal branch stars are above the detection
limits, but difficult to distinguish from young stars with similar colors and
magnitudes. Synthetic color-magnitude diagrams show it is possible to populate
the blue horizontal branch in the halo of Leo A. The models also suggest ~50%
of the total astrated mass in our pointing to be attributed to an ancient (>10
Gyr) stellar population. We conclude that Leo A started to form stars at least
about 9 Gyr ago. Leo A exhibits an extremely low oxygen abundance, of only 3%
of Solar, in its ionized interstellar medium. The existence of old stars in
this very oxygen-deficient galaxy illustrates that a low oxygen abundance does
not preclude a history of early star formation.Comment: 44 pages, 18 figures, accepted for publication in the August 2002
issue of AJ. High resolution figures is available at
http://www.astro.spbu.ru/staff/dio/preprints.htm
Osteomyelitis of the ribs in children: a rare and potentially challenging diagnosis
Background
Rib osteomyelitis is rare in children and can mimic other pathologies. Imaging has a major role in the diagnosing rib osteomyelitis.
Objective
To evaluate clinical presentation and imaging findings in children with rib osteomyelitis.
Materials and methods
We performed a retrospective (2009–2018) study on children with rib osteomyelitis verified by either positive culture or pathology. We excluded children with multifocal osteomyelitis or empyema necessitans. We reviewed medical charts for clinical, laboratory and pathology data, and treatment. All imaging modalities for rib abnormalities were evaluated for presence and location of osteomyelitis and abscess. We calculated descriptive statistics to compare patient demographics, clinical presentation and imaging findings.
Results
The study group included 10 children (6 boys, 4 girls), with an average age of 7.3 years (range, 3 months to 15.9 years). The most common clinical presentations were fever (n=8) and pain (n=5). Eight children had elevated inflammatory indices (leukocytosis, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP]). Localized chest wall swelling was found initially in six children and later in two more children. Rib osteomyelitis was suspected on presentation in only two children. All children had chest radiographs. Rib lytic changes were found on only one chest radiograph, in two of the four ultrasound studies, and in four of eight CTs. Bone marrow signal abnormalities were seen in all eight MRIs. In nine children the osteomyelitis involved the costochondral junction. Six children had an associated abscess. Staphylococcus aureus was cultured in eight children. Osteomyelitis was diagnosed based on pathology in one child with negative cultures.
Conclusion
While rib osteomyelitis is rare, imaging findings of lytic changes at the costochondral junction combined with a history of fever, elevated inflammatory markers or localized soft-tissue swelling in the chest should raise suspicion for this disease
Persistence and Quiescence of Seismicity on Fault Systems
We study the statistics of simulated earthquakes in a quasistatic model of
two parallel heterogeneous faults within a slowly driven elastic tectonic
plate. The probability that one fault remains dormant while the other is active
for a time Dt following the previous activity shift is proportional to the
inverse of Dt to the power 1+x, a result that is robust in the presence of
annealed noise and strength weakening. A mean field theory accounts for the
observed dependence of the persistence exponent x as a function of
heterogeneity and distance between faults. These results continue to hold if
the number of competing faults is increased. This is related to the persistence
phenomenon discovered in a large variety of systems, which specifies how long a
relaxing dynamical system remains in a neighborhood of its initial
configuration. Our persistence exponent is found to vary as a function of
heterogeneity and distance between faults, thus defining a novel universality
class.Comment: 4 pages, 3 figures, Revte
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