408 research outputs found

    Meromorphic traveling wave solutions of the complex cubic-quintic Ginzburg-Landau equation

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    We look for singlevalued solutions of the squared modulus M of the traveling wave reduction of the complex cubic-quintic Ginzburg-Landau equation. Using Clunie's lemma, we first prove that any meromorphic solution M is necessarily elliptic or degenerate elliptic. We then give the two canonical decompositions of the new elliptic solution recently obtained by the subequation method.Comment: 14 pages, no figure, to appear, Acta Applicandae Mathematica

    Phomopsis bougainvilleicola prepatellar bursitis in a renal transplant recipient

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    Prepatellar bursitis is typically a monomicrobial bacterial infection. A fungal cause is rarely identified. We describe a 61-year-old man who had received a renal transplant 21 months prior to presentation whose synovial fluid and surgical specimens grew Phomopsis bougainvilleicola, a pycnidial coelomycete

    On elliptic solutions of the cubic complex one-dimensional Ginzburg-Landau equation

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    The cubic complex one-dimensional Ginzburg-Landau equation is considered. Using the Hone's method, based on the use of the Laurent-series solutions and the residue theorem, we have proved that this equation has neither elliptic standing wave nor elliptic travelling wave solutions. This result amplifies the Hone's result, that this equation has no elliptic travelling wave solutions.Comment: LaTeX, 12 page

    Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions

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    Mitochondrial DNA (mtDNA) mutations are a common cause of primary mitochondrial disorders, and have also been implicated in a broad collection of conditions, including aging, neurodegeneration, and cancer. Prevalent among these pathogenic variants are mtDNA deletions, which show a strong bias for the loss of sequence in the major arc between, but not including, the heavy and light strand origins of replication. Because individual mtDNA deletions can accumulate focally, occur with multiple mixed breakpoints, and in the presence of normal mtDNA sequences, methods that detect broad-spectrum mutations with enhanced sensitivity and limited costs have both research and clinical applications. In this study, we evaluated semi-quantitative and digital PCR-based methods of mtDNA deletion detection using double-stranded reference templates or biological samples. Our aim was to describe key experimental assay parameters that will enable the analysis of low levels or small differences in mtDNA deletion load during disease progression, with limited false-positive detection. We determined that the digital PCR method significantly improved mtDNA deletion detection sensitivity through absolute quantitation, improved precision and reduced assay standard error

    Enhanced Group Analysis and Exact Solutions of Variable Coefficient Semilinear Diffusion Equations with a Power Source

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    A new approach to group classification problems and more general investigations on transformational properties of classes of differential equations is proposed. It is based on mappings between classes of differential equations, generated by families of point transformations. A class of variable coefficient (1+1)-dimensional semilinear reaction-diffusion equations of the general form f(x)ut=(g(x)ux)x+h(x)umf(x)u_t=(g(x)u_x)_x+h(x)u^m (m0,1m\ne0,1) is studied from the symmetry point of view in the framework of the approach proposed. The singular subclass of the equations with m=2m=2 is singled out. The group classifications of the entire class, the singular subclass and their images are performed with respect to both the corresponding (generalized extended) equivalence groups and all point transformations. The set of admissible transformations of the imaged class is exhaustively described in the general case m2m\ne2. The procedure of classification of nonclassical symmetries, which involves mappings between classes of differential equations, is discussed. Wide families of new exact solutions are also constructed for equations from the classes under consideration by the classical method of Lie reductions and by generation of new solutions from known ones for other equations with point transformations of different kinds (such as additional equivalence transformations and mappings between classes of equations).Comment: 40 pages, this is version published in Acta Applicanda Mathematica

    Características métricas de un cuestionario para evaluar la calidad de vida profesional de los médicos cardiólogos

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    Introducción: La calidad de la atención médica de los sistemas de salud parece relacionarse con la satisfacción de los profesionales que los integran; es por ello que el estudio del estrés y la insatisfacción laboral de los profesionales es de especial interés. Por otra parte, es sabido que la medición de la calidad de vida profesional (CVP) puede variar de acuerdo con el instrumento que se utilice, con el entorno organizativo del sistema de salud y con el tipo de profesional o la especialidad que ejerza. Objetivo: Evaluar la factibilidad, la consistencia interna, la capacidad discriminativa y la composición factorial de un cuestionario de CVP aplicado a una población de médicos cardiólogos en la Argentina. Material y métodos: Entre abril y junio de 2007 se propuso un cuestionario anónimo a 717 cardiólogos a fin de evaluar distintos aspectos de la CVP, a saber: percepción de la situación laboral, posibilidad de realización personal y expectativa de futuro. Se realizó un análisis de factores y se midieron la validez de construcción y la confiabilidad del cuestionario. Resultados: El análisis identificó los tres dominios antes señalados. En conjunto, estos tres componentes explicaron el 46% de la variabilidad total del instrumento, nivel exigible para una validez estructural adecuada. Por su parte, el a de Cronbach total del cuestionario fue 0,76. Por último, la confiabilidad se demostró con una buena correlación entre el puntaje total del instrumento y los parciales obtenidos en cada dominio (factor 1: rho = 0,806, p < 0,0001; factor 2: rho = 0,726, p < 0,0001 y factor 3: rho = 0,754, p < 0,0001). Conclusiones: El análisis de las características métricas de este cuestionario demostró la fiabilidad y la validez del instrumento para evaluar la CVP del médico cardiólogo en la Argentina.Facultad de Ciencias Médica
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