2,525 research outputs found

    Renegotiation and Procurement

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    Negotiating fundamental British values: research conversations in church schools

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    In England Church schools seek to express Christian values. They are also obliged by UK government policy, the law, and inspection frameworks, to support fundamental British values. This project sought to find out more about how schools managed and related these two things — how school leaders in schools and academies with a Christian character, negotiate fundamental British values and Christian values in the life of their schools. How do they respond to the dual expectation of cultivating an educational philosophy and ethos that is reflective of or inspired by Christian values, and also supportive of fundamental British values? How do they make sense of these distinctive ideas? Are they viewed as complementary or are their tensions

    The Impact of Dietary Protein Supplementation as Part of a Time Restricted Feeding Eating Pattern on Sleep, Mood, and Body Composition in Adults with Overweight or Obesity

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    Obesity in the United States continues to increase, and effective, long-term weight loss strategies are limited. Time restricted feeding (TRF) is a dietary intervention that has potential to serve as an effective long-term weight loss strategy, however more data is needed to establish the effectiveness of a TRF eating pattern on obesity and its related health outcomes. To our knowledge, manipulation of macronutrient composition during TRF intervention and the effect of TRF on sleep and mood have not been studied. Therefore, the objective of this study was to determine the effect of protein supplementation during TRF on mood, sleep, and metabolic health in overweight and obese adults. Overweight and obese men and women (36.6±7.3 years; BMI: 32.8±6.5) participated in this randomized, controlled 12-week TRF dietary intervention (8 hour eating window with a 16 hour fast). Participants were allocated to one of two groups: 1) control, TRF (n=7) and 2) TRF with whey protein supplementation (25 g/d; n=9). Protein supplements were consumed at the breaking of the fasting period each day. Anthropometrics, sleep (via Pittsburgh Sleep Quality Index Global Sleeping Score; PSQI GSS), total mood disturbances (TMD; via Profile of Mood States (POMS) including six affect states of depression, fatigue, anger, tension, confusion, and vigor subscales), appetite (using visual analog scales), and weighed 3-day dietary intake records were assessed at 0, 4, 8, and 12 weeks. Sleep was also measured at 0 and 12 weeks via wrist Actigraphy. Body composition was measured via DXA at 0 and 12 weeks. Data was analyzed using two-way ANOVA to assess the relationship between interventions and within intervention at each time point. Overall, both interventions improved total body fat percentage (p \u3c0.05) and fat mass to fat-free mass ratio (p \u3c 0.05) over 12 weeks. There was a significant difference in mood states of tension and confusion between intervention groups (p \u3c0.05) and the protein group total mood disturbance was significantly different (p \u3c0.05) between week 1 and 12. However, there was no change in mood within the control group over the 12 week intervention period. Sleep, self-reported via PSQI, did not change between week 1 and week 12 within or between each of the dietary interventions. This pilot study suggests that protein supplementation during TRF has the potential to improve body composition by improving fat mass to fat free mass ratio in overweight or obese individuals. However, additional research is needed with a larger sample size to determine the long-term effect of protein supplementation in combination with TRF on mood, sleep, and body composition

    The Impact of Privatized Management in Urban Public Housing Communities: A Comparative Analysis of Perceived Crime, Neighborhood Problems, and Personal Safety

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    A quasi-experimental design with non-equivalent groups assessed the impact of privatized management on crime and personal safety in large public housing communities in Miami, Florida. A randomly-selected sample (N = 503) of low-income African Americans living in 42 different housing projects were surveyed. Privatized sites had greater mean values for break-ins and thefts (m = 2.03, S.D. = 1.47, p\u3c.01) and vacant apartment usage. Publicly-managed sites had higher mean values for shootings and violence (m = 2.52, S.D. = 1.67, p\u3c.01). While there were no statistically significant differences in perceived personal safety, publicly-managed respondents expressed greater satisfaction with police services. Privatized management did not result in significantly more positive outcomes and social services utilization was associated with less violent crime. Implications are discussed for public housing crime, federal housing policy, and future research

    Impact of Selected Infrared Wavelengths on Inactivation of Microbes on Rough Rice

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    Formation of harmful microbes and their associated mycotoxins on rough rice during storage presents negative socioeconomic impacts to producers and consumers. The objective for this study was to investigate the impact of treating rough rice with selected infrared (IR) wavelengths at different IR intensities and heating durations, followed by a tempering step for further inactivation of microbes (mold and bacteria) on the grain. Freshly-harvested long-grain, hybrid, rough rice (XL 745) with initial moisture content (IMC) of 18.4% wet basis (w.b.) was used. Two-hundred grams (200 g) samples of rice were treated at different IR wavelengths (λ), 3.2, 4.5, and 5.8 μm for 10, 20 and 30 seconds (s); at product-to-emitter gaps of 110, 275, and 440 mm. This was then followed by tempering the grain; putting samples in air-tight jars and holding at a constant temperature of 60 oC for 4 hours (h). Inoculated Petrifilm plates for mold and bacterial analyses were incubated at 25 oC for 120 h and 35 oC for 48 h respectively. Samples treated at wavelength 3.2 μm (product-to-emitter gap 110 mm) for 30 s showed the greatest reduction in mold and bacterial load; approximately 3.11 and 1.09 log reduction in the colony forming unit of mold and bacteria, respectively. Microbial analysis was performed on the rice prior to tempering, then all of the rice was tempered and microbial analysis was performed again to analyze the effectiveness of a tempering step. Tempering treatment further reduced the microbial load at each IR treatment condition. Molds showed more susceptibility to the IR decontamination than bacteria. This study provides useful information on the effectiveness of IR heating and tempering on microbial inactivation on rough rice

    Innovative Financing for Renewable Energy

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    Carbon pollution from fossil-fuel combustion is the largest contributor to climate change worldwide. Renewable energy can materially help to reduce greenhouse gas (GHG) emissions and their principal cause, worldwide dependence on carbon fuels. If our goal is to remain at or below 1990 numbers, then fossil fuels must be phased out of the global energy portfolio. While other factors such as energy inefficiencies in buildings, appliances and transportation, for example; deforestation, farm animal excretion, pipeline leakage, HFCs for refrigeration, black soot and changes in land use also contribute to increased emissions, finding new, innovative ways to empower people to seize the opportunities presented by clean, renewable electricity present an invaluable path to reduce carbon emissions

    Risk factors for chest infection in acute stroke: a prospective cohort study

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    <p><b>Background and Purpose:</b> Pneumonia is a major cause of morbidity and mortality after stroke. We aimed to determine key characteristics that would allow prediction of those patients who are at highest risk for poststroke pneumonia.</p> <p><b>Methods:</b> We studied a series of consecutive patients with acute stroke who were admitted to hospital. Detailed evaluation included the modified National Institutes of Health Stroke Scale; the Abbreviated Mental Test; and measures of swallow, respiratory, and oral health status. Pneumonia was diagnosed by set criteria. Patients were followed up at 3 months after stroke.</p> <p><b>Results:</b> We studied 412 patients, 391 (94.9%) with ischemic stroke and 21 (5.1%) with hemorrhagic stroke; 78 (18.9%) met the study criteria for pneumonia. Subjects who developed pneumonia were older (mean±SD age, 75.9±11.4 vs 64.9±13.9 years), had higher modified National Institutes of Health Stroke Scale scores, a history of chronic obstructive pulmonary disease, lower Abbreviated Mental Test scores, and a higher oral cavity score, and a greater proportion tested positive for bacterial cultures from oral swabs. In binary logistic-regression analysis, independent predictors (P<0.05) of pneumonia were age >65 years, dysarthria or no speech due to aphasia, a modified Rankin Scale score ≥4, an Abbreviated Mental Test score <8, and failure on the water swallow test. The presence of 2 or more of these risk factors carried 90.9% sensitivity and 75.6% specificity for the development of pneumonia.</p> <p><b>Conclusions:</b> Pneumonia after stroke is associated with older age, dysarthria/no speech due to aphasia, severity of poststroke disability, cognitive impairment, and an abnormal water swallow test result. Simple assessment of these variables could be used to identify patients at high risk of developing pneumonia after stroke.</p&gt

    Structural determinants of allosteric regulation in alternatively spliced AMPA receptors

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    AbstractThe flip and flop splice variants of AMPA receptors show strikingly different sensitivity to allosteric regulation by cyclothiazide; heteromers assembled from GluR-A and GIuR-B also exhibit splice variant-dependent differences in efficacy for activation by glutamate and kainate. The sensitivity for attenuation of desensitization by cyclothiazide for homomeric GIuR-A was solely dependent upon exchange of Ser-750 (flip) and Asn-750 (flop), and was unaffected by mutagenesis of other divergent residues. In contrast, substantial alteration of the relative efficacy of glutamate versus kainate required mutation of multiple residues in the flip/flop region. Modulation by cyclothiazide was abolished by mutation of Ser-750 to Gin, the residue found at the homologous site in kainate-preferring subunits, whereas introduction of Ser at this site in GIuR6 imparted sensitivity to cyclothiazide

    Movement ecology and sex are linked to barn owl microbial community composition.

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    The behavioural ecology of host species is likely to affect their microbial communities, because host sex, diet, physiology, and movement behaviour could all potentially influence their microbiota. We studied a wild population of barn owls (Tyto alba) and collected data on their microbiota, movement, diet, size, coloration, and reproduction. The composition of bacterial species differed by the sex of the host and female owls had more diverse bacterial communities than their male counterparts. The abundance of two families of bacteria, Actinomycetaceae and Lactobacillaceae, also varied between the sexes, potentially as a result of sex differences in hormones and immunological function, as has previously been found with Lactobacillaceae in the microbiota of mice. Male and female owls did not differ in the prey they brought to the nest, which suggests that dietary differences are unlikely to underlie the differences in their microbiota. The movement behaviour of the owls was associated with the host microbiota in both males and females because owls that moved further from their nest each day had more diverse bacterial communities than owls that stayed closer to their nests. This novel result suggests that the movement ecology of hosts can impact their microbiota, potentially on the basis of their differential encounters with new bacterial species as the hosts move and forage across the landscape. Overall, we found that many aspects of the microbial community are correlated with the behavioural ecology of the host and that data on the microbiota can aid in generating new hypotheses about host behaviour
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