A Novel Lumbar Motion Segment Classification to Predict Changes in Segmental Sagittal Alignment After Lateral Interbody Fixation.

Study designRetrospective cohort study.ObjectivesLateral interbody fixation is being increasingly used for the correction of segmental sagittal parameters. One factor that affects postoperative correction is the resistance afforded by posterior hypertrophic facet joints in the degenerative lumbar spine. In this article, we describe a novel preoperative motion segment classification system to predict postoperative correction of segmental sagittal alignment after lateral lumbar interbody fusion.MethodsPreoperative computed tomography scans were analyzed for segmental facet osseous anatomy for all patients undergoing lateral lumbar interbody fusion at 3 institutions. Each facet was assigned a facet grade (min = 0, max = 2), and the sum of the bilateral facet grades was the final motion segment grade (MSG; min = 0, max = 4). Preoperative and postoperative segmental lordosis was measured on standing lateral radiographs. Postoperative segmental lordosis was also conveyed as a percentage of the implanted graft lordosis (%GL). Simple linear regression was conducted to predict the postoperative segmental %GL according to MSG.ResultsA total of 36 patients with 59 operated levels were identified. There were 19 levels with MSG 0, 14 levels with MSG 1, 13 levels with MSG 2, 8 levels with MSG 3, and 5 levels with MSG 4. Mean %GL was 115%, 90%, 77%, 43%, and 5% for MSG 0 to 4, respectively. MSG significantly predicted postoperative %GL (P < .01). Each increase in MSG was associated with a 28% decrease in %GL.ConclusionsWe propose a novel facet-based motion segment classification system that significantly predicted postoperative segmental lordosis after lateral lumbar interbody fusion

The Updated Zwicky Catalog (UZC)

The Zwicky Catalog of galaxies (ZC), with m_Zw<=15.5mag, has been the basis for the Center for Astrophysics (CfA) redshift surveys. To date, analyses of the ZC and redshift surveys based on it have relied on heterogeneous sets of galaxy coordinates and redshifts. Here we correct some of the inadequacies of previous catalogs by providing: (1) coordinates with <~2 arcsec errors for all of the Nuzc catalog galaxies, (2) homogeneously estimated redshifts for the majority (98%) of the data taken at the CfA (14,632 spectra), and (3) an estimate of the remaining "blunder" rate for both the CfA redshifts and for those compiled from the literature. For the reanalyzed CfA data we include a calibrated, uniformly determined error and an indication of the presence of emission lines in each spectrum. We provide redshifts for 7,257 galaxies in the CfA2 redshift survey not previously published; for another 5,625 CfA redshifts we list the remeasured or uniformly re-reduced value. Among our new measurements, Nmul are members of UZC "multiplets" associated with the original Zwicky catalog position in the coordinate range where the catalog is 98% complete. These multiplets provide new candidates for examination of tidal interactions among galaxies. All of the new redshifts correspond to UZC galaxies with properties recorded in the CfA redshift compilation known as ZCAT. About 1,000 of our new measurements were motivated either by inadequate signal-to-noise in the original spectrum or by an ambiguous identification of the galaxy associated with a ZCAT redshift. The redshift catalog we include here is ~96% complete to m_Zw<=15.5, and ~98% complete (12,925 galaxies out of a total of 13,150) for the RA(1950) ranges [20h--4h] and [8h--17h] and DEC(1950) range [-2.5d--50d]. (abridged)Comment: 34 pp, 7 figs, PASP 1999, 111, 43

Feynman scaling violation on baryon spectra in pp collisions at LHC and cosmic ray energies

A significant asymmetry in baryon/antibaryon yields in the central region of high energy collisions is observed when the initial state has non-zero baryon charge. This asymmetry is connected with the possibility of baryon charge diffusion in rapidity space. Such a diffusion should decrease the baryon charge in the fragmentation region and translate into the corresponding decrease of the multiplicity of leading baryons. As a result, a new mechanism for Feynman scaling violation in the fragmentation region is obtained. Another numerically more significant reason for the Feynman scaling violation comes from the fact that the average number of cutted Pomerons increases with initial energy. We present the quantitative predictions of the Quark-Gluon String Model (QGSM) for the Feynman scaling violation at LHC energies and at even higher energies that can be important for cosmic ray physics.Comment: 21 pages, 11 figures, and 1 table. arXiv admin note: substantial text overlap with arXiv:1107.1615, arXiv:1007.320

Production of Secondaries in High Energy d+Au Collisions

In the framework of Quark-Gluon String Model we calculate the inclusive spectra of secondaries produced in d+Au collisions at intermediate (CERN SPS) and at much higher (RHIC) energies. The results of numerical calculations at intermediate energies are in reasonable agreement with the data. At RHIC energies numerically large inelastic screening corrections (percolation effects) should be accounted for in calculations. We extract these effects from the existing RHIC experimental data on minimum bias and central d+Au collisions. The predictions for p+Au interactions at LHC energy are also given.Comment: 18 pages and 10 figure

Multiscale modelling of vascular tumour growth in 3D: the roles of domain size & boundary condition

We investigate a three-dimensional multiscale model of vascular tumour growth, which couples blood flow, angiogenesis, vascular remodelling, nutrient/growth factor transport, movement of, and interactions between, normal and tumour cells, and nutrient-dependent cell cycle dynamics within each cell. In particular, we determine how the domain size, aspect ratio and initial vascular network influence the tumour's growth dynamics and its long-time composition. We establish whether it is possible to extrapolate simulation results obtained for small domains to larger ones, by constructing a large simulation domain from a number of identical subdomains, each subsystem initially comprising two parallel parent vessels, with associated cells and diffusible substances. We find that the subsystem is not representative of the full domain and conclude that, for this initial vessel geometry, interactions between adjacent subsystems contribute to the overall growth dynamics. We then show that extrapolation of results from a small subdomain to a larger domain can only be made if the subdomain is sufficiently large and is initialised with a sufficiently complex vascular network. Motivated by these results, we perform simulations to investigate the tumour's response to therapy and show that the probability of tumour elimination in a larger domain can be extrapolated from simulation results on a smaller domain. Finally, we demonstrate how our model may be combined with experimental data, to predict the spatio-temporal evolution of a vascular tumour

E2A/PBX1, MLL/AF4, BCR/ABL (M-BCR), BCR/ABL(m-BCR) gene rearrangements in acute lymphoblastic leukemia in Iranian children

Objectives: The following observation was primarily based on the study of gene fusion in blood and bone marrow cells taken from 68 Iranian children with acute lymphoblastic leukemia (ALL), to compare with healthy population. Methods: Peripheral blood and bone marrow samples obtained from patients with ALL were immunophenotyped to determine the lineage and the level of differentiation. With reverse transcriptase-polymerase chain reaction (RT-PCR), the RNA molecules were analyzed according to Van Dongen et al. protocol to detect fused genes in cell population. Results: Leukemic cell type was identified by cytochemical stains and classified on the basis of FAB classification. Nonetheless the frequencies of E2A/PBX1, MLL/AF4, BCR/ABL (M-BCR) and BCR/ABL(m-BCR) gene transcripts were 1.5, 0, 0 and 4.4 respectively. The positive case of E2A/PBX1 fusion gene had an early pre B and 3 BCR/ABL (m-BCR). Positive cases had an early pre B and pre-B ALL immunophenotype. Conclusions: Early pre-B cells were the most common types in our patients. The RT-PCR was shown to be an ideal method for detecting hybrid transcripts and to estimate the prevalence of the fusion genes in ALL patients. The frequency of these fusion genes in Iranian pediatric ALL patients were found to be similar to some developed countries. Thus, their presence does not seem to be predictive of increasing malignancy, but rather it can challenge the prognostic significance of these rearrangements. © 2018, Holder Demo

Nonlinear interaction of light with Bose-Einstein condensate: new methods to generate subpoissonian light

We consider $\Lambda$-type model of the Bose-Einstein condensate of sodium atoms interacting with the light. Coefficients of the Kerr-nonlinearity in the condensate can achieve large and negative values providing the possibility for effective control of group velocity and dispersion of the probe pulse. We find a regime when the observation of the "slow" and "fast" light propagating without absorption becomes achievable due to strong nonlinearity. An effective two-level quantum model of the system is derived and studied based on the su(2) polynomial deformation approach. We propose an efficient way for generation of subpoissonian fields in the Bose-Einstein condensate at time-scales much shorter than the characteristic decay time in the system. We show that the quantum properties of the probe pulse can be controlled in BEC by the classical coupling field.Comment: 13 pages, 6 figures, 1 tabl

Tetraquarks and Pentaquarks in String Models

We consider the production and decay of multiquark systems in the framework of string models where the hadron structure is determined by valence quarks together with string junctions. We show that the low mass multiquark resonances can be very narrow.Comment: 7 pages, 2 figure

Interaction of non-profit organizations and state structures of the region in the field of adaptive physical culture

The features of the provision of services by state organizations, non-profit organizations within the framework of project activities and grant support in the field of adaptive physical culture and sports are revealed. Based on the results of the analysis of the involvement of non-profit organizations (NPOs) and socially oriented non-profit organizations (SO NPOs) in the scheme of interaction with government agencies, their effectiveness in providing services (works) to the population in the field of adaptive physical culture and sports, a scheme of interaction was developed and proposed to solve the identified problem