Genetic study in patients operated dentally and anesthetized with articaine-epinephrine

Aims: In this study we wanted to figure out if there was a correlation between OPRM1 N40D, TRPV1 I316M, TRPV1 I585V, NOS3 −786T>C and IL6 −174C>G polymorphisms and the response to locally applied articaine-epinephrine anesthetic. Methods: In this observational study, 114 oral cell samples of patients anesthetized with articaine-epinephrine (54 from men 60 from women), were collected from dental centers in Madrid (Spain). High molecular weight DNA was obtained from oral mucosa cells. The analysis of OPRM1 N40D (rs1799971), TRPV1 I316M (rs222747), TRPV1 I585V (rs8065080) and IL6 −174C>G polymorphism was performed through real-time PCR allelic discrimination using TaqMan probes. Polymorphism NOS3 −786T> C (rs2070744) was analyzed using RFLP-PCR. Results: The studied polymorphisms are involved neither in the response to the anesthetic, nor in the intensity of perceived dental pain. However, in a subset of female patients we found that TRPV1 I316M was associated with a delayed onset of anesthesia. Conclusions: There is no association among these polymorphisms and the time elapsed between the application of the anesthetic and the onset of its effect

Quasi-exactly Solvable Lie Superalgebras of Differential Operators

In this paper, we study Lie superalgebras of $2\times 2$ matrix-valued first-order differential operators on the complex line. We first completely classify all such superalgebras of finite dimension. Among the finite-dimensional superalgebras whose odd subspace is nontrivial, we find those admitting a finite-dimensional invariant module of smooth vector-valued functions, and classify all the resulting finite-dimensional modules. The latter Lie superalgebras and their modules are the building blocks in the construction of QES quantum mechanical models for spin 1/2 particles in one dimension.Comment: LaTeX2e using the amstex and amssymb packages, 24 page

Four dimensional Lie symmetry algebras and fourth order ordinary differential equations

Realizations of four dimensional Lie algebras as vector fields in the plane are explicitly constructed. Fourth order ordinary differential equations which admit such Lie symmetry algebras are derived. The route to their integration is described.Comment: 12 page

Is it possible to store spotted wolffish (Anarhichas minor) sperm by refrigeration?

Spotted wolffish Anarhichas minor reproduction in captivity is dependent on in vitro fertilization. However, it is often challenging to acquire sufficient fresh sperm to fertilize the eggs that are obtained. In this study, we evaluate the possibility to store spotted wolffish sperm by refrigeration. Spotted wolffish sperm has the particularity that is already motile on stripping, and currently it is not possible to immobilize and reactivate. Thus, sperm refrigeration protocols should focus in extending this motility period that usually lasts up to 2 days. In a first experiment, we evaluated the possibility that the motility period of the sperm was limited by contamination with urine. The urea concentration in the sperm obtained both by stripping (17.10 ± 1.98 mg/dL) and directly from the testis (12.59 ± 2.37 mg/dL) was similar (p > 0.05), which indicate that the sperm collection method used avoid contamination with urine. Afterwards, we tested the possibility that the sperm motility period was limited by energy stores. The ATP concentration (initial value 5.65 ± 0.86 nmol/109 cells) remained stable (p = 0.099) during 30 h after sperm collection, and similar values (p = 0.329) were recorded at end of sperm storage in both diluted (3.88 ± 1.35 nmol/109 cells) and undiluted samples (4.76 ± 1.08 nmol/109). This indicates that the low intracellular ATP consumption, derived from the slow sperm motility, can probably be compensated rapidly enough by mitochondrial synthesis of ATP in the spotted wolffish sperm. In both experiments, diluted sperm kept higher percentage of motile cells during the storage time.info:eu-repo/semantics/publishedVersio

Quasi-exact solvability beyond the SL(2) algebraization

We present evidence to suggest that the study of one dimensional quasi-exactly solvable (QES) models in quantum mechanics should be extended beyond the usual \sla(2) approach. The motivation is twofold: We first show that certain quasi-exactly solvable potentials constructed with the \sla(2) Lie algebraic method allow for a new larger portion of the spectrum to be obtained algebraically. This is done via another algebraization in which the algebraic hamiltonian cannot be expressed as a polynomial in the generators of \sla(2). We then show an example of a new quasi-exactly solvable potential which cannot be obtained within the Lie-algebraic approach.Comment: Submitted to the proceedings of the 2005 Dubna workshop on superintegrabilit

On the families of orthogonal polynomials associated to the Razavy potential

We show that there are two different families of (weakly) orthogonal polynomials associated to the quasi-exactly solvable Razavy potential V(x)=(\z \cosh 2x-M)^2 (\z>0, $M\in\mathbf N$). One of these families encompasses the four sets of orthogonal polynomials recently found by Khare and Mandal, while the other one is new. These results are extended to the related periodic potential U(x)=-(\z \cos 2x -M)^2, for which we also construct two different families of weakly orthogonal polynomials. We prove that either of these two families yields the ground state (when $M$ is odd) and the lowest lying gaps in the energy spectrum of the latter periodic potential up to and including the $(M-1)^{\rm th}$ gap and having the same parity as $M-1$. Moreover, we show that the algebraic eigenfunctions obtained in this way are the well-known finite solutions of the Whittaker--Hill (or Hill's three-term) periodic differential equation. Thus, the foregoing results provide a Lie-algebraic justification of the fact that the Whittaker--Hill equation (unlike, for instance, Mathieu's equation) admits finite solutions.Comment: Typeset in LaTeX2e using amsmath, amssymb, epic, epsfig, float (24 pages, 1 figure

Experimental adiabatic vortex ratchet effect in Nb films with asymmetric pinning trap

Nb films grown on top of an array of asymmetric pinning centers show a vortex ratchet effect. A net flow of vortices is induced when the vortex lattice is driven by fluctuating forces on an array of pinning centers without reflection symmetry. This effect occurs in the adiabatic regime and it could be mimiced only by reversible DC driven forces