Proyecto de diseño y construcción de una planta de elaboración de espárragos en conserva en polígono industrial de Malpica (Zaragoza)

El presente proyecto de título PROYECTO DE DISEÑO Y CONSTRUCCIÓN DE UNA PLANTA DE ELABORACIÓN DE ESPÁRRAGOS EN CONSERVA EN POLÍGONO INDUSTRIAL DE MALPICA (ZARAGOZA) consiste en el cálculo y diseño una Planta de elaboración de espárragos en conserva. La necesidad de construir dicho proyecto era procesar, mediante diversos tratamientos tecnológicos, los espárragos (Asparagus officinalis) cultivados en la Huerta del Bajo Gállego y dentro del Valle del Ebro para obtener un producto apto para el consumo. De este modo, imponer la calidad del espárrago autóctono en el sector agroalimentario. La planta procesará alrededor de 2000 kg al día de espárragos, produciendo latas de conserva de espárragos enteros, yemas y tallos.Se construirá en una parcela ubicada en el Polígono Industrial Malpica en Zaragoza ocupando una superficie de 2.720 m2. La nave tendrá unas dimensiones de 48 m de longitud y 20 de ancho, con una altura de 6 metros de pilar y la cubierta será a dos aguas con una pendiente del 20%.El proceso productivo consiste en la recepción y almacenaje de la materia prima, el corte y lavado, escaldado, enfriamiento, pelado, envasado, dosificación del líquido de gobierno, precalentamiento, cerrado, esterilización y enfriamiento de los espárragos. El proyecto consta de los siguientes documentos: -Documento nº1: Memoria y Anejos a la memoria: Anejo I. Antecedentes y objeto del proyecto, Anejo II. Proceso Productivo, Anejo III. Balance de Materia, Anejo IV. Balance de Energía, Anejo V. Caldera y depósito de gasóleo, Anejo VI. Dimensionado de equipos y zonas, Anejo VII. Instalación Frigorífica, Anejo VIII. Instalación de Fontanería, Anejo X. Instalación de Saneamiento, Anejo XI. Sistema de Análisis de riesgos y control de puntos críticos, Anejo XII. Instalación de Iluminación, Anejo XIII. Instalación Eléctrica, Anejo XIV. Instalación de Protección contra Incendios, Anejo XV. Estudio económico y Anejo XVI. Bibliografía. -Documento nº2: Planos. -Documento nº3: Pliego de condiciones. -Documento nº4: Presupuesto y -Documento nº5: Estudio de Seguridad y Salud.<br /

Influence of Structure-modifying Agents in the Synthesis of Zr-doped SBA-15 Silica and Their Use as Catalysts in the Furfural Hydrogenation to Obtain High Value-added Products through the Meerwein-Ponndorf-Verley Reduction

Zr-doped mesoporous silicas with different textural parameters have been synthesized in the presence of structure-modifying agents, and then characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), N2 adsorption-desorption at -196 ºC, NH3 thermoprogrammed desorption (NH3–TPD), CO2 thermoprogrammed desorption (CO2–TPD), and X-ray photoelectron spectroscopy (XPS). These porous materials were evaluated in the furfural hydrogenation through the Meerwein-Ponndorf-Verley (MPV) reaction. The catalytic results indicate that the catalyst synthesized under hydrothermal conditions and adding a pore expander agent is more active and selective to furfuryl alcohol. However, the Zr-doped porous silica catalysts that were synthesized at room temperature, which possess narrow pore sizes, tend to form i-propyl furfuryland difurfuryl ethers, coming from etherification between furfuryl alcohol (FOL) and isopropanol molecules (used as H-donor) by a SN2 mechanism.This research was funded by the Ministry of Economy and Competitiveness (Spain) (grant numbers: CTQ2015-64226-C3-3-R, IEDI-2016-00743), Junta de Andalucía (Spain) (P12-RNM-1565), and FEDER (European Union) funds

Magnetitas utilizadas para la obtención de alcohol furfurílico a partir de furfural mediante transferencia catalítica de hidrógeno

El furfural es considerado como una molécula plataforma debido a su alta reactividad en procesos de hidrogenación, oxidación, alquilación o deshidratación, originando una gran variedad de productos de alto valor añadido. En la presente comunicación se presentan los resultados obtenidos en el proceso de hidrogenación de furfural mediante transferencia catalítica de hidrógeno a partir de la reacción de Meerwein, Ponndorf y Verley, usando magnetitas como catalizador ácido, donde se ha variado la relación molar Fe(II)/Fe(III) empleada para su síntesis.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Mixed Oxides Derived from Hydrotalcites Mg/Al Active in the Catalytic Transfer Hydrogenation of Furfural to Furfuryl Alcohol

Herein, a family of Mg/Al hydrotalcites was synthesized as catalytic precursors of MgAlOx mixed oxides. Both hydrotalcites and mixed oxides were characterized and the mixed oxides were tested in the reduction of furfural to yield furfuryl alcohol by MPV reaction using isopropanol as hydrogen donor. Different catalytic parameters were tested, such as the type of alcohol, calcination temperature of the hydrotalcite, and reaction temperature. Furfural and isopropanol were adsorbed on the MgAl-3 catalyst to follow the species adsorbed on the catalyst by FTIR analysis. The results showed that the isopropanol was activated as isopropoxide and furfural changed the adsorption site with increasing temperature but maintaining the h1-conformation. The catalytic performances were associated with the basicity of the catalysts and the deactivation processes have been attributed to the existence of adsorbed species on the surface, mainly due to furfural-derived compounds. The catalysts were reused in three consecutive cycles showing a sharp drop of catalytic activity. To recover the activity, the catalysts were calcined at 500 °C but the activity was only partially recovered. The XPS analysis after reactivation showed that the catalyst surface was modified due to the segregation of hydroxides of Mg and Al.This research was funded by the Spanish Ministry of Science and Innovation (PID2021-122736OB-C42), FEDER (European Union) funds (PID2021-122736OB-C42, P20-00375, UMA20-FEDERJA88). Partial funding for open access charge: Universidad de Málag

Short–term effects of air pollution and noise on emergency hospital admissions in Madrid and economic assessment

The aim of this study was to study the effect of air pollution and noise has on the population in Madrid Community (MAR) in the period 2013–2018, and its economic impact

Short-term impact of noise, other air pollutants and meteorological factors on emergency hospital mental health admissions in the Madrid region

A number of environmental factors, such as air pollution, noise in urbanised settings and meteorological-type variables, may give rise to important effects on human health. In recent years, many studies have confirmed the relation between various mental disorders and these factors, with a possible impact on the increase in emergency hospital admissions due to these causes. The aim of this study was to analyse the impact of a range of environmental factors on daily emergency hospital admissions due to mental disorders in the Madrid Autonomous Region (MAR), across the period 2013–2018

Engaging the Public with CCUS: Reflection on a European Project Approach

The aim of this paper is to share our approach for a societal engagement and participation process that is implemented as part of two sequential research projects on CCUS. The two projects are both funded under the European Union’s (EU) Horizon 2020 research program. The first one, STRATEGY CCUS (2019-2022), develops strategic development plans for eight regions in South-East Europe; the second, Pilot STRATEGY (2021-2026), partly builds on the first project; Pilot STRATEGY aims at enabling three of the eight regions to start developing their storage resources concretely and to support two further regions in continuing to explore CCUS as an option. Both projects were designed in a way that they integrate geological, technical and economic research with social sciences, with a focus on the regional level. The paper provides an overview on the concept, objectives and the methodologies for the engagement process. It further includes reflections identifying room for improvement and provides recommendations for other projects. Overall, we find that the situation is characterized by low levels of awareness regarding CCUS, but some openness to discuss it. Specific expectations vary and the societal view is not always in line with the current scientific knowledge and the technological development. Important recommendations include building strong interdisciplinary teams that also implement processes for self-reflection.info:eu-repo/semantics/publishedVersio

Risk Of Recurrence After Withdrawal Of Anticoagulation In Patients With Unprovoked Venous Thromboembolism: External Validation Of The Vienna Nomogram And The Dash Prediction Score

[ES] Introducción: Las escalas predictivas de recurrencias de ETV son útiles para decidir la duración del tratamiento anticoagulante. Aunque hay varias escalas, desconocemos la aplicabilidad de las mismas en nuestro medio. Por ello nos planteamos validar el modelo predictivo DASH y el nomograma de Viena a 12 meses.-- Métodos: Estudio retrospectivo de pacientes consecutivos no seleccionados con ETV no provocada desde 2006 hasta 2014. Comparamos la capacidad de predecir recurrencias de ETV de la escala DASH y el nomograma de Viena. La validación se realizó estratificando a los pacientes como de bajo o alto riesgo, según cada escala (discriminación) y comparando las recurrencias observadas frente a las esperadas (calibración).-- Resultados: De 353 pacientes evaluados, se analizaron 195, con una edad media de 53,5+/-19 años. Hubo 21 recurrencias a 1 año (10,8%, IC95%: 6,8-16%). Según la escala DASH, fueron catalogados de bajo riesgo el 42%, observando ETV recurrente en el grupo de bajo fue del 4,9% (IC95%: 1,3-12%) vs. el grupo de alto riesgo en que fue del 15% (IC95%: 9-23%) (p<0,05). Según el nomograma de Viena, fueron catalogados de bajo riesgo el 30%, observando ETV recurrente en el grupo de bajo vs. alto riesgo en el 4,2% (IC95%: 0,5-14%) vs. 16,2% (IC95%: 9,9-24,4%) (p<0,05).-- Conclusiones: Nuestro estudio valida la escala DASH y el nomograma de Viena en nuestra población. El modelo predictivo DASH sería el más aconsejable, tanto por su sencillez como por la capacidad de identificar a más pacientes de bajo riesgo frente al nomograma de Viena (42% vs. 30%).[EN ] Introduction: Scales for predicting venous thromboembolism (VTE) recurrence are useful for deciding the duration of the anticoagulant treatment. Although there are several scales, the most appropriate for our setting has not been identified. For this reason, we aimed to validate the DASH prediction score and the Vienna nomogram at 12 months.-- Methods: This was a retrospective study of unselected consecutive VTE patients seen between 2006 and 2014. We compared the ability of the DASH score and the Vienna nomogram to predict recurrences of VTE. The validation was performed by stratifying patients as low-risk or high-risk, according to each scale (discrimination) and comparing the observed recurrence with the expected rate (calibration).-- Results: Of 353 patients evaluated, 195 were analyzed, with an average age of 53.5 ± 19 years. There were 21 recurrences in 1 year (10.8%, 95% CI: 6.8%-16%). According to the DASH score, 42% were classified as low risk, and the rate of VTE recurrence in this group was 4.9% (95% CI: 1.3%-12%) vs. the high-risk group that was 15% (95% CI: 9%-23%) (p <.05). According to the Vienna nomogram, 30% were classified as low risk, and the rate of VTE recurrence in the low risk group vs. the high risk group was 4.2% (95% CI:0.5%-14%) vs. 16.2% (95% CI: 9.9%-24.4%) (p <.05).-- Conclusions: Our study validates the DASH score and the Vienna nomogram in our population. The DASH prediction score may be the most advisable, both because of its simplicity and its ability to identify more low-risk patients than the Vienna nomogram (42% vs. 30%).Peer reviewe

An Experimental DUAL Model of Advanced Liver Damage

Individuals exhibiting an intermediate alcohol drinking pattern in conjunction with signs of metabolic risk present clinical features of both alcohol-associated and metabolic-associated fatty liver diseases. However, such combination remains an unexplored area of great interest, given the increasing number of patients affected. In the present study, we aimed to develop a preclinical DUAL (alcohol-associated liver disease plus metabolic-associated fatty liver disease) model in mice. C57BL/6 mice received 10% vol/vol alcohol in sweetened drinking water in combination with a Western diet for 10, 23, and 52 weeks (DUAL model). Animals fed with DUAL diet elicited a significant increase in body mass index accompanied by a pronounced hypertrophy of adipocytes, hypercholesterolemia, and hyperglycemia. Significant liver damage was characterized by elevated plasma alanine aminotransferase and lactate dehydrogenase levels, extensive hepatomegaly, hepatocyte enlargement, ballooning, steatosis, hepatic cell death, and compensatory proliferation. Notably, DUAL animals developed lobular inflammation and advanced hepatic fibrosis. Sequentially, bridging cirrhotic changes were frequently observed after 12 months. Bulk RNA-sequencing analysis indicated that dysregulated molecular pathways in DUAL mice were similar to those of patients with steatohepatitis. Conclusion: Our DUAL model is characterized by obesity, glucose intolerance, liver damage, prominent steatohepatitis and fibrosis, as well as inflammation and fibrosis in white adipose tissue. Altogether, the DUAL model mimics all histological, metabolic, and transcriptomic gene signatures of human advanced steatohepatitis, and therefore serves as a preclinical tool for the development of therapeutic targets.Supported by EXOHEP-CM (S2017/BMD-3727), Ramón y Cajal (RYC-2014-15242 and RYC-2015-17438), NanoLiver-CM (Y2018/NMT-4949), COST Action (CA17112), AMMF (2018/117), ERAB (EA 18/14), MINECO Retos (SAF2016-78711 and SAF2017-87919-R), and German Research Foundation (DFG NE 2128/2-1, SFB 1382-403224013/A02, and SFB/TRR57/P04). FJC is a Gilead Research Liver Scholar. The research group belongs to the validated Research group Ref. 970935 “Liver Pathophysiology”, 920631 “Lymphocyte immunology”, 920361 “Immunogenética e inmunología de las mucosas” and IBL-6 (imas12-associated). FG and KZ are Chinese Scholarship Council (CSC) fellows. O.E.-V is supported by Beca FPI (associated to MINECO SAF2017-87919R) and R.B.-U. by Contratos predoctorales de personal investigador en formación UCM-Banco Santander (CT63/19)

Investigación en Danza CSIC

INVESTIGACIÓN EN DANZA CSIC es un portal que recoge la actividad científica sobre danza en el contexto del Instituto de Historia del Consejo Superior de Investigaciones Científicas, sus proyectos de investigación e iniciativas vinculadasPeer reviewe