3 research outputs found
Chemical Composition, Antifungal and Herbicidal Effects of Essential Oil Isolated from Chersodoma argentina
Effects of natural weathering on the degradation of alkaline‐treated peanut shell filled recycled polypropylene composites
Synthesis, regioselectivity, and DFT analysis of new antioxidant pyrazolo[4,3-c]quinoline-3,4-diones
The condensation of hydrazine, N-methylhydrazine, and N-phenylhydrazine with ethyl 4-chloro-2-oxo- 1,2-dihydroquinoline-3-carboxylate derivatives has been investigated. As a result, 12 new antioxidant pyrazolo[4,3- c]quinolin-3,4-diones were obtained with good to high yields. When two cross-products could be possible, only one isomer bearing the methyl or the phenyl group at the N1 position is isolated and unequivocally characterized using 1D and 2D NMR techniques, FT-IR, and combustion analyses. DFT analysis of the reaction mechanism was carried out in the Pearson’s hard soft acid base framework, confirming the assigned structure to the observed pyrazolo[4,3-c]quinolin-3,4-diones. These calculations indicate a favored kinetic control for the synthesized pyrazolo[4,3- c]quinolin-3,4-diones compared to its possible regioisomer.The authors thank the Regional University
Hospital of Besanc¸on for support (France). Financial support from
Regional Council of Franche-Comté (Besanc¸on, France) is also
acknowledged. Computations have been performed on the supercomputer
facilities of the Me´socentre de calcul de Franche-Comté
(Besanc¸on, France)Peer Reviewe